Results 101 to 110 of about 398,844 (320)
Ergodicity of Markov chain Monte Carlo with reversible proposal [PDF]
We describe ergodic properties of some Metropolis-Hastings (MH) algorithms for heavy-tailed target distributions. The analysis usually falls into sub-geometric ergodicity framework but we prove that the mixed preconditioned Crank-Nicolson (MpCN) algorithm has geometric ergodicity even for heavy-tailed target distributions.
arxiv
MYH11 (myosin heavy chain) [PDF]
Review on MYH11 (myosin heavy chain), with data on DNA, on the protein encoded, and where the gene is implicated.
openaire +2 more sources
Hypoxia promotes the epithelial‐mesenchymal transition (EMT) of renal tubular epithelial cells via the SIRT1‐FoxO1‐FoxO3‐autophagy pathway, thereby resulting in the fibrosis of renal tubular epithelial cells. Activation of SIRT1 or induction of autophagy inhibits this process, alleviating hypoxia‐induced fibrosis.
Guangyu Wang+6 more
wiley +1 more source
The two subset recurrent property of Markov chains [PDF]
This paper proposes a new type of recurrence where we divide the Markov chains into intervals that start when the chain enters into a subset A, then sample another subset B far away from A and end when the chain again return to A. The length of these intervals have the same distribution and if A and B are far apart, almost independent of each other.
arxiv
Toward Design Principles for Biomolecular Condensates for Metabolic Pathways
Biomolecular condensates are membrane‐less compartments found through‐out nature which can serve as reaction crucibles for biochemical processes. This review explores the design strategies underlying how condensates can be used in biotechnology to enhance multistep enzyme cascades including enhancement by mass action and substrate channeling, and ...
Alain A.M. André+3 more
wiley +1 more source
The partial sequence of two large peptides from the N-terminal half of heavy chains from normal rabbit immunoglobulin G [PDF]
John J. Cebra+2 more
openalex +1 more source
The Regulation of Trace Metal Elements in Cancer Ferroptosis
The induction of ferroptosis inhibits tumor growth, enhances anticancer efficacy, and overcomes drug resistance. Recent evidence shows nonferrous metal elements play a role in ferroptosis. This review focuses on how trace metals regulate ferroptosis processes like iron accumulation, lipid peroxidation, and antioxidant defense.
Xiaoyan Wang+5 more
wiley +1 more source
Multiple strategies have been developed to facilitate the efficient production of bispecific IgG (BsIgG) in single host cells. For example, we previously demonstrated near quantitative (≥90%) formation of BsIgG of different species and isotypes by ...
Kamal Kishore Joshi+6 more
doaj +1 more source
EVIDENCE FOR MULTIPLE GENE CONTROL OF A SINGLE POLYPEPTIDE CHAIN: THE HEAVY CHAIN OF RABBIT IMMUNOGLOBULIN [PDF]
Marian Elliott Koshland+2 more
openalex +1 more source
On generic chaining and the smallest singular value of random matrices with heavy tails [PDF]
We present a very general chaining method which allows one to control the supremum of the empirical process $\sup_{h \in H} |N^{-1}\sum_{i=1}^N h^2(X_i)-\E h^2|$ in rather general situations. We use this method to establish two main results. First, a quantitative (non asymptotic) version of the classical Bai-Yin Theorem on the singular values of a ...
arxiv