Results 151 to 160 of about 1,211,483 (357)

A Sustainable Biotechnology Approach for Mineral Separation

Advanced Functional Materials, EarlyView.
Silver‑binding peptides are first identified through phage‐display screening, and then engineered into multifunctional and responsive peptides or proteins. These tailored biomolecules can selectively capture and aggregate silver particles or ions from complex mixtures, enabling rapid and efficient silver separation and recovery.
Guangze Yang, Yun Liu, Shankar Raj Devkota, Yue Hui, Ruilin Zhao, Yang Li, David A. Weitz, Chun‐Xia Zhao   +7 more
wiley   +1 more source

Conserved heavy/light contacts and germline preferences revealed by a large-scale analysis of natively paired human antibody sequences and structural data

Communications Biology
Understanding the pairing preferences and structural interactions between antibody heavy and light chains can enhance our ability to design more effective and specific therapeutic antibodies.
Pawel Dudzic, Dawid Chomicz, Weronika Bielska, Igor Jaszczyszyn, Michał Zieliński, Bartosz Janusz, Sonia Wróbel, Marguerite-Marie Le Pannérer, Andrew Philips, Prabakaran Ponraj, Sandeep Kumar, Konrad Krawczyk   +11 more
doaj   +1 more source

Atrial and ventricular cardiac myosins contain different heavy chain species [PDF]

, 1978
Irwin L. Flink, Jeffrey H. Rader, Surath K. Banerjee, Eugene Morkin   +3 more
openalex   +1 more source

Endocytic Programming via Porous Silicon Nanoparticles Enhances TLR4 Nanoagonist Potency for Macrophage‐Mediated Immunotherapy

Advanced Functional Materials, EarlyView.
Porous silicon nanoparticles (PSiNPs) reprogram macrophage endocytosis of manganese@albumin‐based TLR4 nanoagonists, driving TRIF‐biased TLR4 signaling, eliciting robust proinflammatory responses, and potentiating macrophage‐mediated immunotherapeutic effects against NSCLC.
Xiaomei Zhang, Huiying Li, Shuodan Huang, Linxuan Zhang, Yan Gao, Ruoran Wang, Xiaoyu Wang, Hélder A. Santos, Zhenyu Yin, Bing Xia   +9 more
wiley   +1 more source

Resistance of Cloned 1F5 Chimeric Anti-CD20 Antibody Heavy-Chain Gene to DNA Polymerase due to a Predicted Hairpin Structure

Research in Molecular Medicine, 2016
Background: Formation of secondary structure such as DNA hairpins or loops may influence molecular genetics methods and PCR based approaches necessary for genetic engineering, in addition to gene regulation.
Fatemeh Khademi, Pantea Mohammadi, Kheirollah Yari, Ali Mostafaie   +3 more
doaj  

Myosin from cross‐reinnervated cat muscles. Evidence for reciprocal transformation of heavy chains [PDF]

, 1975
Alan G. Weeds, Keith Burridge
openalex   +1 more source

Probing Early Particle‐Cell Membrane Interactions via Single‐Cell and Single‐Particle Interaction Analysis

Advanced Functional Materials, EarlyView.
The pre‐internalization phase of endocytosis remains poorly characterized at single‐cell levels. Single‐cell pre‐internalization mechanics are investigated using advanced robotic techniques. Cancer cells exhibit biphasic adhesion – rapid initial binding followed by reinforcement – while fibroblasts show gradual engagement.
Houari Bettahar, Christos Tapeinos, Oğulcan Işıtman, Carmine D'Amico, Alexandra Correia, Hélder A. Santos, Quan Zhou   +6 more
wiley   +1 more source

Inhibitory effect of Endostar on HIF-1 with upregulation of MHC-I in lung cancer cells

Cancer Biology & Therapy
Endostar is a human recombinant endostatin which is an attractive anti-angiogenesis protein. Because inefficient antigen presenting MHC class I expression (which can be downregulated by HIF-1) is an important strategy for cancer immune evasion, besides ...
Ming-Zhen Zhao, Hong-Fei Zheng, Jing-Na Wang, Yan-Min Zhang, Hai-Jing Wang, Zhi-Wei Zhao   +5 more
doaj   +1 more source

SUBGROUPS OF AMINO ACID SEQUENCES IN THE VARIABLE REGIONS OF IMMUNOGLOBULIN HEAVY CHAINS

, 1969
Bruce A. Cunningham, Mollie N. Pflumm, Urs Rutisha User, Gerald M. Edelman   +3 more
openalex   +1 more source

Hybridization studies with an antibody heavy chain mRNA [PDF]

, 1974
Alejandra Bernardini, Susumu Tonegawa
openalex   +1 more source