Results 11 to 20 of about 1,130,735 (339)

Immunoglobulin heavy chain exclusion in the shark. [PDF]

open access: yesPLoS Biology, 2008
The adaptive immune system depends on specific antigen receptors, immunoglobulins (Ig) in B lymphocytes and T cell receptors (TCR) in T lymphocytes.
Karolina Malecek   +6 more
doaj   +5 more sources

Two Cases of Heavy Chain MGUS [PDF]

open access: yesCase Reports in Oncological Medicine, 2016
Heavy chain diseases are rare variants of B-cell lymphomas that produce one of three classes of immunoglobulin heavy chains, without corresponding light chains. We describe two patients with asymptomatic heavy chain monoclonal gammopathy.
Jan Van Keer   +4 more
doaj   +4 more sources

Flatness of heavy chain systems [PDF]

open access: yesProceedings of the 41st IEEE Conference on Decision and Control, 2002., 2001
The paper deals with systems that consist of a fixed length heavy chain suspended from a cart moving along an horizontal line. The whole system is controlled by the motion of the cart. Various types of chains are considered: simple homogeneous chains and variable density chains with or without a weight attached to its free end.
Pierre Rouchon, Nicolas Petit
openaire   +2 more sources

Novel exons and splice variants in the human antibody heavy chain identified by single cell and single molecule sequencing. [PDF]

open access: yesPLoS ONE, 2015
Antibody heavy chains contain a variable and a constant region. The constant region of the antibody heavy chain is encoded by multiple groups of exons which define the isotype and therefore many functional characteristics of the antibody.
Christopher Vollmers   +3 more
doaj   +1 more source

Gamma heavy chain disease associated with T-cell large granular lymphocyte lymphoproliferative disorder: case report and literature review.

open access: yesMediterranean Journal of Hematology and Infectious Diseases, 2023
Heavy chain diseases are rare B-cell neoplasms consisting of the production of a monoclonal immunoglobulin composed of the only heavy chain without corresponding light chains.
Maria Laura Bisegna   +5 more
doaj   +1 more source

A role for Tctex-1 (DYNLT1) in controlling primary cilium length [PDF]

open access: yes, 2011
The microtubule motor complex cytoplasmic dynein is known to be involved in multiple processes including endomembrane organization and trafficking, mitosis, and microtubule organization.
MacCarthy-Morrogh, LJ   +3 more
core   +1 more source

γ Heavy chain disease [PDF]

open access: yesBlood, 2019
![Figure][1] A 78-year-old woman from Sudan with presumed tuberculous lymphadenitis without preexisting autoimmune disease presented with fatigue, persistent fever, hepatosplenomegaly, and generalized lymphadenopathy.
Vidya Nagrale, Lois Richard
openaire   +3 more sources

A simple way to increase recovery of the expressed VH and VL genes in single-sorted human B cells

open access: yesBioTechniques, 2019
Cloning VH and VL genes from individual antigen-specific B cells is an attractive approach for producing monoclonal antibodies of the desired specificity.
Sergey V Guselnikov   +4 more
doaj   +1 more source

IgG light chain-independent secretion of heavy chain dimers: consequence for therapeutic antibody production and design [PDF]

open access: yes, 2017
Rodent monoclonal antibodies with specificity towards important biological targets are developed for therapeutic use by a process of humanisation. This process involves the creation of molecules, which retain the specificity of the rodent antibody but ...
Angal   +34 more
core   +1 more source

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