Results 11 to 20 of about 4,061,678 (356)

Water Contamination by Heavy Metals and their Toxic Effect on Aquaculture and Human Health through Food Chain

Letters in Applied NanoBioScience, 2020
Heavy metals are metals with relatively high density and toxic at very low concentrations. The common heavy metal pollutants can be traced everywhere in minimal quantities.
Swaroop S. Sonone, Swapnali Jadhav, M. S. Sankhla, Rajeev Kumar   +3 more
semanticscholar   +1 more source

Clathrin heavy chain is important for viability, oviposition, embryogenesis and, possibly, systemic RNAi response in the predatory mite Metaseiulus occidentalis. [PDF]

PLoS ONE, 2014
Clathrin heavy chain has been shown to be important for viability, embryogenesis, and RNA interference (RNAi) in arthropods such as Drosophila melanogaster.
Ke Wu, Marjorie A Hoy
doaj   +1 more source

The immunoglobulin A isotype of the Arabian camel (Camelus dromedarius) preserves the dualistic structure of unconventional single-domain and canonical heavy chains

Frontiers in Immunology, 2023
IntroductionThe evolution of adaptive immunity in Camelidae resulted in the concurrent expression of classic heterotetrameric and unconventional homodimeric heavy chain-only IgG antibodies.
Walter Conca, Walter Conca, Walter Conca, Soad M. Saleh, Rana Al-Rabiah, Ranjit Singh Parhar, Mahmoud Abd-Elnaeim, Hussein Al-Hindas, Alexander Tinson, Katharina Birgit Kroell, Klaus Roman Liedl, Kate Collison, Uday Kishore, Futwan Al-Mohanna, Futwan Al-Mohanna   +14 more
doaj   +1 more source

A Review of the Health Implications of Heavy Metals in Food Chain in Nigeria

TheScientificWorldJournal, 2020
Heavy metals such as Zn, Pb, Fe, and Cu are abundant in the environment and contribute largely to the sustainability and equilibrium of ecosystem processes.
U. Nkwunonwo, P. O. Odika, Nneka I. Onyia   +2 more
semanticscholar   +1 more source

Common light chain chickens produce human antibodies of high affinity and broad epitope coverage for the engineering of bispecifics

mAbs, 2021
Bispecific antibodies are an important and growing segment in antibody therapeutics, particularly in the immuno-oncology space. Manufacturing of a bispecific antibody with two different heavy chains is greatly simplified if the light chains can be the ...
Kathryn H. Ching, Kimberley Berg, Kevin Reynolds, Darlene Pedersen, Alba Macias, Yasmina N. Abdiche, William D. Harriman, Philip A. Leighton   +7 more
doaj   +1 more source

The Effect of Botulinum Neurotoxin Serotype a Heavy Chain on the Growth Related Proteins and Neurite Outgrowth after Spinal Cord Injury in Rats

Toxins, 2018
(1) Background: The botulinum toxin A (BoNT-A) heavy chain (HC) can stimulate the growth of primary motor neurites. (2) Methods: A recombinant BoNT/A HC was injected locally plus interval intrathecal catheter of BoNT/A HC to rats with ipsilateral semi ...
Ya-Fang Wang, Fu Liu, Jing Lan, Juan Bai, Xia-Qing Li   +4 more
doaj   +1 more source

γ Heavy chain disease [PDF]

Blood, 2019
![Figure][1] A 78-year-old woman from Sudan with presumed tuberculous lymphadenitis without preexisting autoimmune disease presented with fatigue, persistent fever, hepatosplenomegaly, and generalized lymphadenopathy.
Vidya, Nagrale, Lois, Richard
openaire   +2 more sources

Phytoremediation: A Promising Approach for Revegetation of Heavy Metal-Polluted Land

Frontiers in Plant Science, 2020
Heavy metal accumulation in soil has been rapidly increased due to various natural processes and anthropogenic (industrial) activities. As heavy metals are non-biodegradable, they persist in the environment, have potential to enter the food chain through
An Yan, Yamin Wang, S. Tan, Mohamed Lokman Mohd Yusof, Subhadip Ghosh, Zhong Chen   +5 more
semanticscholar   +1 more source

Novel exons and splice variants in the human antibody heavy chain identified by single cell and single molecule sequencing. [PDF]

PLoS ONE, 2015
Antibody heavy chains contain a variable and a constant region. The constant region of the antibody heavy chain is encoded by multiple groups of exons which define the isotype and therefore many functional characteristics of the antibody.
Christopher Vollmers, Lolita Penland, Jad N Kanbar, Stephen R Quake   +3 more
doaj   +1 more source

Nanobodies and Nanobody-Based Human Heavy Chain Antibodies As Antitumor Therapeutics

Frontiers in Immunology, 2017
Monoclonal antibodies have revolutionized cancer therapy. However, delivery to tumor cells in vivo is hampered by the large size (150 kDa) of conventional antibodies. The minimal target recognition module of a conventional antibody is composed of two non-
P. Bannas, J. Hambach, F. Koch-Nolte
semanticscholar   +1 more source