Results 11 to 20 of about 285,431 (226)

Heavy-Chain Deposition Disease [PDF]

open access: bronzeNew England Journal of Medicine, 1993
Comment inOminous consequences of immunoglobulin deposition. [N Engl J Med. 1993]
Aucouturier, Pierre   +7 more
openaire   +5 more sources

Gamma-heavy chain disease [PDF]

open access: hybridKlinicka Onkologie, 2020
Gamma-heavy chain disease is a rare disease, described so far in approximately 150 cases. The aim of this work was laboratory dia-gnostics of immunoglobulin heavy chain disease.A 60-year-old patient was referred to the University Hospital in Ostrava for suspected marginal zone lymphoma from gastric bio-psy.
Tomas Jelinek   +3 more
openaire   +3 more sources

Alpha heavy chain disease [PDF]

open access: goldAtlas of Genetics and Cytogenetics in Oncology and Haematology, 2018
lpha heavy chain disease (HCD) is the most prevalent form of heavy chain diseases, a rare family of syndromes associated with or representing a B cell malignancy variant. The hallmark characteristic and the pathogenic mechanism of HCD is the synthesis of a mutant, misfolded immunoglobulin heavy chain (IgH) which cannot form a quaternary conformation ...
Bianchi, Giada, Anderson, Kenneth C
openaire   +3 more sources

Multiple myeloma shows no intra-disease clustering of immunoglobulin heavy chain genes

open access: goldHaematologica, 2012
Background Characterization of the immunoglobulin gene repertoire has improved our understanding of the immunopathogenesis of lymphoid tumors. Early B-lymphocyte precursors of multiple myeloma are known to exist and might be susceptible to antigenic ...
Simone Ferrero   +24 more
doaj   +3 more sources

Zero-state Coupled Markov Switching Count Models for Spatio-temporal Infectious Disease Spread [PDF]

open access: yesJournal of the Royal Statistical Society: Series C (Applied Statistics) (2022) 1-24, Early View, 2021
Spatio-temporal counts of infectious disease cases often contain an excess of zeros. With existing zero inflated count models applied to such data it is difficult to quantify space-time heterogeneity in the effects of disease spread between areas. Also, existing methods do not allow for separate dynamics to affect the reemergence and persistence of the
arxiv   +1 more source

γ Heavy chain disease [PDF]

open access: yesBlood, 2019
![Figure][1] A 78-year-old woman from Sudan with presumed tuberculous lymphadenitis without preexisting autoimmune disease presented with fatigue, persistent fever, hepatosplenomegaly, and generalized lymphadenopathy.
Vidya Nagrale, Lois Richard
openaire   +3 more sources

Disease X vaccine production and supply chains: risk assessing healthcare systems operating with artificial intelligence and industry 4.0 [PDF]

open access: yes, 2023
A set of six algorithmic solutions is presented for resolving vaccine production and supply chain bottlenecks. A different set of algorithmic solutions is presented for forecasting risks during a Disease X event.
arxiv   +1 more source

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