Results 51 to 60 of about 20,916 (244)

In vitro sensitivity of malignant melanoma cells lines to photon and heavy ion radiation

Clinical and Translational Radiation Oncology, 2019
Background: The role of radiotherapy in malignant melanoma is still in discussion due to its relative resistance to radiation. In various literature, heavy ions show a higher relative biological effectiveness than photons.
K.P. Aninditha, K.J. Weber, S. Brons, J. Debus, H. Hauswald   +4 more
doaj   +1 more source

Dosimetric characteristics of a new linear accelerator under gated operation. [PDF]

, 2006
Respiratory gated radiotherapy may allow reduction of the treatment margins, thus sparing healthy tissue and/or allowing dose escalation to the tumor. However, current commissioning and quality assurance of linear accelerators do not include evaluation ...
Kriminski, Sergey, Li, Alex N, Solberg, Timothy D   +2 more
core   +1 more source

HEAVY ION RADIOTHERAPY

Le Journal de Physique Colloques, 1989
After a short historical note on the origins of radiotherapy, this paper reviews the main specifications of radiations used for therapy. One main characteristic is the dose distribution in the patient's body, the other is the so-called "oxygen enhancement ratio" (O.E.R.) which is related to the linear energy transfer (L.E.T.).
openaire   +2 more sources

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

Molecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena, Karin Teien Lande, Eva Diaz, Ana Vilar, Juan Cueva, Efigenia Arias, Victoria Sampayo, Alicia Abalo, Nerea González, Eva Colás, Antonio Gil‐Moreno, Miguel Abal, Gema Moreno‐Bueno, Therese Sørlie, Kristina Lindemann, Laura Muinelo‐Romay   +15 more
wiley   +1 more source

Clinical outcome after particle therapy for meningiomas of the skull base: toxicity and local control in patients treated with active rasterscanning [PDF]

, 2018
Background: Meningiomas of the skull base account for 25–30% of all meningiomas. Due to the complex structure of the cranial base and its close proximity to critical structures, surgery is often associated with substantial morbidity.
Bougatf, Nina, Combs, Stephanie E., Czech, Maja, Debus, Jürgen, Habermehl, Daniel, Jäkel, Oliver, Kessel, Kerstin A., Rieken, Stefan, Shafie, Rami A., Weber, Dorothea   +9 more
core   +1 more source

Cutaneous Melanoma Drives Metabolic Changes in the Aged Bone Marrow Immune Microenvironment

Aging and Cancer, EarlyView.
Melanoma, the deadliest form of skin cancer, increasingly affects older adults. Our study reveals that melanoma induces changes in iron and lipid levels in the bone marrow, impacting immune cell populations and increasing susceptibility to ferroptosis.
Alexis E. Carey, Murilo Ramos Rocha, Cheyenne Palm, Vania Wang, Denys Balandin, Ethan Black, Kevin Y. Zhang, Fan Huang, Daniel J. Zabransky, Yash Chhabra, Mareike Peters, Gabriel Ghiaur, Ashani Weeraratna   +12 more
wiley   +1 more source

Technical Note: Improving the workflow in a carbon ion therapy center with custom software for enhanced patient care

Technical Innovations & Patient Support in Radiation Oncology
Carbon-ion radiation therapy (CIRT) is an up-and-coming modality for cancer treatment. Implementation of CIRT requires collaboration among specialists like radiation oncologists, medical physicists, and other healthcare professionals.
Sridhar Yaddanapudi, Yushi Wakisaka, Keith M. Furutani, Masashi Yagi, Shinichi Shimizu, Chris J. Beltran   +5 more
doaj   +1 more source

Identification of the Kupffer cell-derived circulating IGFBP-3 as a universal radiation biomarker for heavy ion, proton, and X-ray exposure

Ecotoxicology and Environmental Safety, 2023
The minimally invasive biomarkers that can facilitate a rapid dose assessment are valuable for the early medical treatment when accidental or occupational radiation exposure happens.
Hao Bai, Jufang Wang, Qiaojuan Wang, Yaxiong Chen, Guoying Miao, Tongshan Zhang, Junrui Hua, Yanan Zhang, Jinpeng He, Nan Ding, Heng Zhou, Li Sui, Wenjun Wei   +12 more
doaj   +1 more source

A Dual-Beam Irradiation Facility for a Novel Hybrid Cancer Therapy

, 2012
In this paper we present the main ideas and discuss both the feasibility and the conceptual design of a novel hybrid technique and equipment for an experimental cancer therapy based on the simultaneous and/or sequential application of two beams, namely a
A Doria, A Rosen, AG Pakhomov, AR Orlando, B Born, BS Jang, C Furse, C Yu, D Satoh, DT Pooley, E Bründermann, E Giovenale, EA Nanni, G Andocs, GJ Hyland, GJ Wilmink, GJ Wilmink, H Frohlich, H Kamada, H Kamada, J Wang, JR Reimers, K Mileva, MR Scarfì, Norio Miyoshi, P Wusta, PH Siegel, R Barth, RF Barth, S Banik, S Sabchevski, S Sabchevski, Shintaro Ishiyama, Svilen Petrov Sabchevski, T Idehara, T Idehara, T Idehara, T Sato, T Tatsukawa, T Tatsukawa, T Tatsukawa, T Tatsukawa, TA Buchholz, Toshiaki Tatsukawa, Toshitaka Idehara, Y Nakagawa   +45 more
core   +1 more source

Chordoma. Clinical characteristics, management and prognosis of a case series of 25 patients [PDF]

, 2010
Background: Adequate surgery still remains the only curative treatment of chordoma. Interesting clinical data on advanced disease with molecularly targeted therapies were reported.Methods: We described the clinical outcome of a series of chordoma ...
Virginia Ferraresi, Carmen Nuzzo, Carmine Zoccali, Ferdinando Marandino, Antonello Vidiri, Nicola Salducca, Massimo Zeuli, Diana Giannarelli, Francesco Cognetti, Roberto Biagini, A Jemal, R Chugh, CE Peña, JM Mirra, NL Higinbotham, C Catton, PW Chambers, S Boriani, F Tzortzidis, D Baratti, D Schulz-Ertner, DC Weber, GF Fleming, E Tamborini, S Stacchiotti, H Hof, K Schönegger, ZL Gokaslan, HY Zhang, P Bergh, KL Foweraker, PA Forsyth, BJ Cummings, P Gabriele, GC Feigl, HD Suit, M Austin-Seymour, M Austin-Seymour, G Noël, R Chugh, PG Scimeca, A Azzarelli, PG Casali, PG Casali, PM Weinberger, S Stacchiotti   +45 more
core   +1 more source