Results 81 to 90 of about 101,813 (256)
Advanced Science, EarlyView.A subset of tumor‐associated macrophages (TAMs) characterized by SPP1 expression is discovered, which may remodel the tumor microenvironment by potentially promoting CD4+ T cell stress and maintaining epithelial cell stemness through SPP1‐CD44, thereby potentially contributing to the proliferation and migration of tumor cells, which has been verified ...
Xinhui Yuan +5 more
wiley +1 more source
Does urbanisation have an impact on the trophic ecology of the Algerian hedgehog Atelerix algirus in northern Algeria? [PDF]
Biodiversity Data JournalThe Algerian hedgehog, which is an endemic Mediterranean species, is a nocturnal and terrestrial insectivorous mammal. Atelerix algirus’ populations are widespread in various habitats comprising human agglomeration, such as rural, suburban or natural ...
Amina Zidane +3 more
doaj +3 more sources
Barcoding Hedgehog for Intracellular Transport
, 2011 Cholesterol modification may alter the intracellular localization of Hedgehog, thereby influencing where Hedgehog is released.
Thomas B. Kornberg
core +1 more source
Acinar‐Derived Organoids Reveal Stage‐Specific Control of Acinar Plasticity
Advanced Science, EarlyView.An acinar‐derived organoid system maintains adult pancreatic acinar identity ex vivo, converts it along an ordered acinar‐to‐ductal‐like trajectory, and then partially restores it. Each transition carries its own signal requirement, with EGF/EGFR initiating conversion and a staged glucocorticoid–IGF1R switch driving redifferentiation.
Yongfei Hou +10 more
wiley +1 more source
Ontogeny of murine bony semicircular canal form
The Anatomical Record, EarlyView.Abstract The labyrinthine geometry and functional anatomy of the semicircular canals have intrigued scientists for decades, and there has been considerable interest in understanding how these complex structures grow and develop with evidence emerging from human studies that size maturation occurs exceptionally early by comparison with other systems ...
Marcela Cárdenas‐Serna +1 more
wiley +1 more source
The “costly son” hypothesis: Sons exacerbate obstetrical dilemmas in humans and other mammals
The Anatomical Record, EarlyView.Abstract Human childbirth has often been considered uniquely difficult among mammals, yet recent evidence suggests that obstructed labor and fetopelvic disproportion are widespread across placental mammals. Here, we propose the “costly son” hypothesis: because male offspring are typically larger at birth, they impose greater obstetric risk on mothers ...
Nicole D. S. Grunstra +1 more
wiley +1 more source
Follicle Stimulating Hormone in Cattle Breeding: Fundamentals, Innovations, and Scope
Animal Research and One Health, EarlyView.FSH is crucial in cattle reproduction, with exogenous administration enhancing breeding and embryo production. Recombinant FSH offers advantages over pituitary‐extracted variants, including fewer injections, reduced stress, and safer production. These innovations improve breeding efficiency, optimize reproductive outcomes, and contribute to sustainable
Muhammad Shahzad +7 more
wiley +1 more source
Osteoblasts in Bone Physiology—Mini Review
Rambam Maimonides Medical Journal, 2012 Bone structural integrity and shape are maintained by removal of old matrix by osteoclasts and in-situ synthesis of new bone by osteoblasts. These cells comprise the basic multicellular unit (BMU).
Orit Rosenberg, Michael Soudry
doaj +1 more source
Anatomy Museum: An educational resource for community anatomy education
Anatomical Sciences Education, EarlyView.Abstract University Community Outreach Programs play an important role in the education of Health Sciences students by providing experiences that extend beyond traditional classroom learning and strengthen the integration between teaching, research, and social engagement.
Ticiana Sidorenko de Oliveira Capote +6 more
wiley +1 more source
Solasonine, A Natural Glycoalkaloid Compound, Inhibits Gli-Mediated Transcriptional Activity
Molecules, 2016 The major obstacle limiting the efficacy of current Smoothened (Smo) inhibitors is the primary and acquired resistance mainly caused by Smo mutations and Gli amplification.
Jun Yang, Wenjing Huang, Wenfu Tan
doaj +1 more source