Results 161 to 170 of about 31,386 (239)

The Role of Long Noncoding RNAs in Modulation of Stress Granules in Cancer

Journal of Cellular and Molecular Medicine, Volume 30, Issue 13, July 2026.
ABSTRACT Stress granules are dynamic cellular structures that arise in response to stress. They play an important role in cancer cell survival by modulating multiple stress responses. Long noncoding RNAs (lncRNAs) have been identified as crucial regulators of stress granule (SG) dynamics, influencing cancer development and treatment resistance. LncRNAs
Nazlı Şevval Menemenli, Bünyamin Akgül   +1 more
wiley   +1 more source

Parkinson's Disease Cell Transplantation Therapy: A New Dawn With Pluripotent Stem Cell–Based Therapy

Journal of Neurochemistry, Volume 170, Issue 7, July 2026.
Parkinson's disease (PD) is characterized by the progressive loss of dopaminergic neurons in the midbrain. Cell transplantation, which aims to replace these lost neurons, has emerged as a promising approach. Early attempts using fetal ventral mesencephalic tissue showed proof‐of‐concept, with some patients achieving long‐term motor improvement. However,
Etsuro Nakanishi, Hodaka Yamakado, Nobukatsu Sawamoto, Jun Takahashi, Ryosuke Takahashi   +4 more
wiley   +1 more source

Efficacy and Safety of Sonidegib in the Treatment of Multiple Facial Cutaneous Basal Cell Carcinomas with Chronic Renal Insufficiency: A Case Report. [PDF]

Clin Cosmet Investig Dermatol
Jing W, Yang J, Gong Z, Lei W, Zhang Z, Rao WB, Ai Y.   +6 more
europepmc   +1 more source

Flavouring Group Evaluation 216 Revision 3 (FGE.216Rev3): Consideration of the genotoxic potential of α,β‐unsaturated 2‐phenyl‐2‐alkenals from subgroup 3.3 of FGE.19

EFSA Journal, Volume 24, Issue 7, July 2026.
Abstract The EFSA Panel on Food Additives and Flavourings (FAF) evaluated the genotoxic potential of two flavouring substances, 2‐phenylcrotonaldehyde [FL‐no: 05.062] and 5‐methyl‐2‐phenylhex‐2‐enal [FL‐no: 05.099] from subgroup 3.3 of FGE.19, in the Flavouring Group Evaluation 216 revision 3 (FGE.216Rev3).
EFSA Panel on Food Additives and Flavourings (FAF), Laurence Castle, Monica Andreassen, Gabriele Aquilina, Maria Bastos, Polly Boon, Biagio Fallico, Rex FitzGerald, María José Frutos Fernández, Bettina Grasl‐Kraupp, Ursula Gundert‐Remy, Rainer Gürtler, Eric Houdeau, Marcin Kurek, Henriqueta Louro, Patricia Morales, Sabina Passamonti, Claudia Bolognesi, Eugenia Cordelli, Gisela Degen, Karl‐Heinz Engel, Maria Carfí, Alessandra Tosato, Carla Martino   +23 more
wiley   +1 more source

Targeting Glioblastoma Stem Cells: Therapeutic Strategies and Clinical Perspectives. [PDF]

Cancers (Basel)
Rachamala HR, Lourembam SD, Mukhopadhyay D, Angom RS.   +3 more
europepmc   +1 more source

Reduced Mechanical Tactile Stimulation Under Space Microgravity Affects Synaptic Signaling and Contributes to Neuromuscular Aging in Caenorhabditis elegans

The FASEB Journal, Volume 40, Issue 12, 30 June 2026.
Microgravity (μG) reduces mechanical tactile stimulation in Caenorhabditis elegans, causing neuromuscular decline, altered gene expression, synaptic defects, and accelerated aging phenotypes. The gentle‐touch mechanoreceptor MEC‐4 mediates μG‐induced body length reduction and extracellular matrix gene downregulation.
Atsushi Higashitani, Je‐Hyun Moon, Jong‐In Hwang, Nahoko Higashitani, Toko Hashizume, Ahmad Aisha Abu, Kazuki Ooizumi, Ibuki Sazuka, Yoshimitsu Hashizume, Masumi Umehara, Alfredo V. Alcantara Jr, Ban‐seok Kim, Timothy Etheridge, Nathaniel J. Szewczyk, Takaaki Abe, Jin I. Lee, Akira Higashibata   +16 more
wiley   +1 more source

Refractory Morpheaform Basal Cell Carcinoma Successfully Treated with Oral Sonidegib. [PDF]

Clin Cosmet Investig Dermatol
Zhang Y, Zheng J, Li X, Wang Y, Fang F, Wang Z, Bu W.   +6 more
europepmc   +1 more source

Therapeutic Strategies Targeting the Tumor-Stromal Microenvironment in Colorectal Cancer: A Narrative Review. [PDF]

Target Oncol
Heilijgers F, Bakker MC, van Hest B, Franken I, Speetjens FM, Peeters KCMJ, Roodhart J, Mesker WE.   +7 more
europepmc   +1 more source

Comparative analysis of zebrafish, organoid, and organ-on-chip models in breast cancer research. [PDF]

Biotechnol Notes
Alzaharani R, Alghadmi MA, Amiri M.
europepmc   +1 more source

Discovery of Novel Hedgehog Signaling Inhibitor

Discovery of Novel Hedgehog Signaling Inhibitor
Thesis
openaire