Results 291 to 300 of about 4,715,625 (390)

Non-cell-autonomous regulation of mTORC2 by Hedgehog signaling maintains lipid homeostasis. [PDF]

Cell Rep
VanDerMolen KR, Newman MA, Breen PC, Gao Y, Huff LA, Dowen RH.   +5 more
europepmc   +1 more source

Population genomic analysis of Mahoenui giant wētā (Deinacrida mahoenui) reveals minimal reduction in genomic diversity following translocation

Insect Conservation and Diversity, EarlyView.
The Mahoenui giant wētā is an Aotearoa New Zealand endemic insect of conservation concern, having been extirpated from the majority of its natural range before rediscovery in the 1960s. We assess the genetic impacts of a translocation from the remaining population in the Mahoenui Giant Wētā Scientific Reserve to establish a new population on Mahurangi ...
Natalie J. Forsdick, Duckchul Park, Danny Thornburrow, Corinne Watts, Thomas R. Buckley   +4 more
wiley   +1 more source

Hedgehog Signaling during Gut Formation in the Freshwater Leech, Helobdella austinensis.

Cells Tissues Organs
Medina-Jiménez BI, Kwak HJ, Aryal YP, Lee CJ, Jeong GH, Pyo IH, Park H, Kim S, Park SC, Cho SJ.   +9 more
europepmc   +1 more source

Itraconazole promotes melanoma cells apoptosis via inhibiting hedgehog signaling pathway-mediated autophagy. [PDF]

Front Pharmacol
Jin S, Liu X, Cai L, Yan J, Li L, Dong H, Gao Y, Zhu X, Zhang C, Xu X.   +9 more
europepmc   +1 more source

Mechanistic insights into dental stem cells‐derived exosomes in regenerative endodontics

International Endodontic Journal, EarlyView.
Abstract Background Dental pulp is a richly vascularised and innervated tissue vital for tooth vitality, sensory function, and structural integrity. While conventional root canal therapy effectively treats necrotic permanent teeth, it irreversibly eliminates pulp vitality, potentially increasing the risk of secondary infections and long‐term structural
Paras Ahmad, Nathan Estrin, Nima Farshidfar, Yufeng Zhang, Richard J. Miron   +4 more
wiley   +1 more source

Author Correction: The Hira complex regulates Gli3R-dependent transcription in Hedgehog signaling and medulloblastoma cell growth and migration. [PDF]

Sci Rep
Skarżyńska W, Baran B, Niewiadomski P.
europepmc   +1 more source

Upregulated NOTCH2 Expression Is Implicated in the Clinical Aggressiveness of Atypical Fibroxanthoma and Pleomorphic Dermal Sarcoma

International Journal of Dermatology, EarlyView.
ABSTRACT Background Atypical fibroxanthoma (AFX) and pleomorphic dermal sarcoma (PDS) represent clinicopathological variants of a spectrum. It is known that AFX and PDS tumors harbor frequent NOTCH1/2 mutations. However, the expression of Notch signaling pathway‐associated proteins in both tumor cells has not been studied before.
Yi‐Pei Lee, Fahimeh Razegphpour, Emilia Sorescu, Markus Stücker, Thilo Gambichler   +4 more
wiley   +1 more source

Hedgehog signaling directs cell differentiation and plays a critical role in tendon enthesis healing. [PDF]

NPJ Regen Med
Fang F, Casserly M, Robbins J, Thomopoulos S.   +3 more
europepmc   +1 more source

LncRNA wires up Hippo and Hedgehog signaling to reprogramme glucose metabolism

EMBO Journal, 2017
Xin Zheng, Han Han, Guang-ping Liu, Yanxiu Ma, Ruo-lang Pan, L. Sang, Rui-hua Li, Luo-jia Yang, J. Marks, Wenqi Wang, Aifu Lin   +10 more
semanticscholar   +1 more source

Single‐Step Genome‐Wide Association Study of Factors for Evaluated and Linearly Scored Traits in Swedish Warmblood Horses

Journal of Animal Breeding and Genetics, EarlyView.
ABSTRACT Swedish Warmblood horses (SWB) are bred for show jumping and/or dressage with young horse test scores as indicator traits. This study aimed to investigate possible candidate genes and regions of importance for evaluated and linearly scored young horse test traits.
Anahit Nazari‐Ghadikolaei, W. Freddy Fikse, Åsa Gelinder Viklund, Sofia Mikko, Susanne Eriksson   +4 more
wiley   +1 more source