Results 341 to 350 of about 4,715,625 (390)

Decoding the pancreatic cancer microenvironment: The multifaceted regulation of microRNAs

Clinical and Translational Medicine, Volume 15, Issue 7, July 2025.
miRNAs play multiple roles in the tumour microenvironment of pancreatic cancer, including angiogenesis, interactions with cancer‐associated fibroblasts, the immune microenvironment, exosome communication, the neural microenvironment and metabolic reprogramming.
Jie Ji, Dandan Jin, Junpeng Zhao, Xudong Xie, Yujie Jiao, Xuyang He, Yuxuan Huang, Lirong Zhou, Mingbing Xiao, Xiaolei Cao   +9 more
wiley   +1 more source

Reappraisal of the Roles of the Sonic Hedgehog Signaling Pathway in Hepatocellular Carcinoma. [PDF]

Cancers (Basel)
Jeng KS, Chang CF, Tsang YM, Sheen IS, Jeng CJ.   +4 more
europepmc   +1 more source

Hybridization and Asymmetrical Introgression Between the Vulnerable Gray‐Headed Chickadee and a More Abundant Congener, the Boreal Chickadee: Implications for Conservation

Ecology and Evolution, Volume 15, Issue 7, July 2025.
We assess genetic evidence of hybridization between gray‐headed chickadees and boreal chickadees using mitochondrial DNA and nuclear DNA sequencing of individuals from historical and contemporary time periods. We detected two early‐generation hybrids among the historical boreal chickadee samples and none within the contemporary boreal chickadee samples
Matthew R. Armstrong, Robert E. Wilson, James A. Johnson, Travis L. Booms, Callie F. Gesmundo, Zachary M. Pohlen, Paul B. Leonard, Sarah A. Sonsthagen   +7 more
wiley   +1 more source

Numb positively regulates Hedgehog signaling at the ciliary pocket. [PDF]

Nat Commun
Liu X, Yam PT, Schlienger S, Cai E, Zhang J, Chen WJ, Torres Gutierrez O, Jimenez Amilburu V, Ramamurthy V, Ting AY, Branon TC, Cayouette M, Gen R, Marks T, Kong JH, Charron F, Ge X.   +16 more
europepmc   +1 more source

Enhancing performance of detection dog field surveys through experimental transects

The Journal of Wildlife Management, Volume 89, Issue 5, July 2025.
We evaluated performance parameters for a scat detection dog through assessment transects and compared these results with field survey data from the same dog‐team over a 4‐year period. From this, we derived valuable insights into the suitability of assessment transects for dog evaluation and how they can inform field performance.
Tim Hofmann, Anne Schmidt‐Küntzel, Stijn Verschueren, S. Francois Jenkins, Stephan Neumann, Johannes Signer, Niko Balkenhol, Laurie Marker   +7 more
wiley   +1 more source

Positive regulation of Hedgehog signaling via phosphorylation of GLI2/GLI3 by DYRK2 kinase. [PDF]

Proc Natl Acad Sci U S A
Yoshida S, Kawamura A, Aoki K, Wiriyasermkul P, Sugimoto S, Tomiyoshi J, Tajima A, Ishida Y, Katoh Y, Tsukada T, Tsuneoka Y, Yamada K, Nagamori S, Nakayama K, Yoshida K.   +14 more
europepmc   +1 more source

A recurrent mosaic mutation in SMO, encoding the hedgehog signal transducer smoothened, is the major cause of Curry-Jones syndrome [PDF]

, 2016
et al,, Grange, Dorothy K
core   +1 more source

Macrophage Signaling Pathways in Health and Disease: From Bench to Bedside Applications

MedComm, Volume 6, Issue 7, July 2025.
Macrophage functions in phagocytosis, tissue repair, immune regulation, and neuronal network protection. And graphic abract image in the attachment. ABSTRACT Macrophages exhibit remarkable functional plasticity by dynamically polarizing into proinflammatory or antiinflammatory subsets in response to microenvironmental cues. This duality underpins their
Yongquan Chi, Haipeng Jiang, Yiyuan Yin, Xinyu Zhou, Yiyouyou Shao, Yongsheng Li, Jianhua Rao   +6 more
wiley   +1 more source

Hyperactivation of Hedgehog signaling impedes myelin development and repair via cholesterol dysregulation in oligodendrocytes. [PDF]

iScience
Fang M, Wang X, Chen L, Li F, Wang S, Shen L, Yang H, Sun L, Wang X, Yang J, Qiu M, Xu X.   +11 more
europepmc   +1 more source

Fish species lifespan prediction from promoter cytosine‐phosphate‐guanine density

Molecular Ecology Resources, Volume 25, Issue 5, July 2025.
Abstract Lifespan is a key attribute of a species' life cycle and varies extensively among major lineages of animals. In fish, lifespan varies by several orders of magnitude, with reported values ranging from less than 1 year to approximately 400 years.
Alyssa M. Budd, Benjamin Mayne, Oliver Berry, Simon Jarman   +3 more
wiley   +1 more source