Results 211 to 220 of about 834,809 (383)

RORα Coordinates Reciprocal Signaling in Cerebellar Development through Sonic hedgehog and Calcium-Dependent Pathways

, 2003
David Gold, Sung Hee Baek, Nicholas J. Schork, David W. Rose, DeLaine D. Larsen, Benjamin D. Sachs, Michael G. Rosenfeld, Bruce A. Hamilton   +7 more
openalex   +1 more source

Cell Apoptosis and Glucocorticoid‐Induced Osteonecrosis

Med Research, EarlyView.
The review identifies glucocorticoid‐induced osteocyte/osteoblast apoptosis as central to femoral head osteonecrosis (GION), mediated through STAT1‐caspase‐3, PI3K/Akt, Wnt/β‐catenin, and oxidative stress pathways. Emerging therapies targeting these pathways (e.g., HIF‐1α stabilization, AMPK activation, and exosome‐mediated miRNA delivery) show ...
Xiumei Tang, Yanyun Pang, Peijia Zhu, Zhengdong Zhang, Sen Guo, Zhijian Wei, Wenzhao Wang, Bin Ning   +7 more
wiley   +1 more source

Targeting the hedgehog signaling pathway to improve tendon-to-bone integration. [PDF]

Osteoarthritis Cartilage, 2023
Kamalitdinov TB, Fujino K, Keith Lang S, Jiang X, Madi R, Evans MK, Zgonis MH, Kuntz AF, Dyment NA.   +8 more
europepmc   +1 more source

Regulation and function of the sonic hedgehog (Shh) signal transduction pathway in isolated gastric parietal cells

, 2003
Vinzenz Stepan, Saravanan Ramamoorthy, H. Nitsche, Jung Park, Andrea Todisco   +4 more
openalex   +1 more source

A comprehensive review on adaptive plasticity and recovery mechanisms post‐acquired brain injury

Neuroprotection, EarlyView.
This figure illustrates the dynamic process of neurogenesis following brain injury, focusing on the roles of neural stem and progenitor cells at the injury site. Key mechanisms include axonal sprouting, synaptogenesis, dendritic remodeling, and brain‐derived neurotrophic factor signaling via TrkB receptors.
Ravi Kumar Rajan
wiley   +1 more source

The acetylation GLI1 affects arsenical-induced renal fibrosis by mediating the Hedgehog signalling pathway

Ecotoxicology and Environmental Safety
Arsenic exposure by drinking water is a key challenge in the field of public health worldwide. Research has found a connection between arsenic exposure and renal fibrosis, yet the mechanisms behind this are still unclear. In this study, rats were exposed
Pinya Liu, Yating Wang, Peiyu Jin, Qing Zhou, Liang Pei, Shuhua Xi   +5 more
doaj  

Indian hedgehog signaling pathway: Expression and regulation in pancreatic cancer

, 2004
Hany Kayed, Jörg Kleeff, Shereen Keleg, Junchau Guo, Knut Ketterer, Pascal O. Berberat, Nathalia A. Giese, Iréne Esposito, Thomas Giese, Markus W. Büchler, Helmut Frieß   +10 more
openalex   +1 more source

Epidermal Growth Factor Receptor Signaling Synergizes with Hedgehog/GLI in Oncogenic Transformation via Activation of the MEK/ERK/JUN Pathway [PDF]

, 2009
Harald Schnidar, Markus Eberl, Stefan Klingler, Doris Mangelberger, Maria Kasper, Cornelia Hauser‐Kronberger, Gerhard Regl, Renate Kroismayr, Richard Moriggl, Maria Sibilia, Fritz Aberger   +10 more
openalex   +1 more source

The Role of Hedgehog Signaling Pathway in Head and Neck Squamous Cell Carcinoma. [PDF]

Cells, 2023
Cierpikowski P, Leszczyszyn A, Bar J.
europepmc   +1 more source

Antbears and underground melons: A highly specialized seed dispersal mutualism mediated by scent

PLANTS, PEOPLE, PLANET, EarlyView.
Seed dispersal is critical for the establishment and persistence of populations of most plant species. We investigated the seed dispersal biology of an African melon, Cucumis humifructus, which is closely related to cultivated cucumbers and watermelons but differs in that it buries its fruits deep underground.
Steven D. Johnson, Anka Eichhoff, Jeremy J. Midgley   +2 more
wiley   +1 more source