Results 231 to 240 of about 247,901 (376)

has_circ_0070512 promotes prostate cancer progression by regulating the miR-338-3p/hedgehog signaling pathway. [PDF]

Cancer Sci, 2023
Zhang P, Gao H, Yan R, Yu L, Xia C, Yang D.   +5 more
europepmc   +1 more source

Implication of GPRASP2 in the Proliferation and Hair Cell‐Forming of Cochlear Supporting Cells

Cell Proliferation, EarlyView.
Schematic diagram of GPRASP2‐mediated SCs proliferation and HCs formation. GPRASP2 deficiency results in increased lysosomal degradation of SMO. GPRASP2‐mediated SMO/GLI1 signalling promotes SC proliferation, which contributes to HC formation. GPRASP2‐mediated SMO/β‐catenin signalling is implicated in HCs fate specification and differentiation ...
Jing Cai, Kun Huang, Wenrui Li, Tianming Wang, Shen Yue, Zhibin Chen, Guangqian Xing, Qinjun Wei, Jun Yao, Xin Cao   +9 more
wiley   +1 more source

Expression of Hedgehog Signaling Pathway Proteins in Basal Cell Carcinoma: Clinicopathologic Study. [PDF]

Clin Cosmet Investig Dermatol, 2022
Deng LJ, Jia M, Luo SY, Li FZ, Fang S.
europepmc   +1 more source

Human Midbrain Organoids Enriched With Dopaminergic Neurons for Long‐Term Functional Evaluation

Cell Proliferation, EarlyView.
We optimised a protocol that combines developmental patterning with mechanical cut to produce pint‐sized midbrain organoids, with diameters less than 300 μm, suitable for long‐term evaluation, along with a comprehensive functional assay system consisting of calcium transient assay, neurite extension assay, and multielectrode array assay. ABSTRACT Human
Xinyue Wang, Gaoying Sun, Mingming Tang, Da Li, Jianhuan Qi, Chuanyue Wang, Yukai Wang, Baoyang Hu   +7 more
wiley   +1 more source

Hypoxia activates the hedgehog signaling pathway in a ligand‐independent manner by upregulation of Smo transcription in pancreatic cancer [PDF]

, 2011
Hideya Onishi, Masaya Kai, Seiichi Odate, Hironori Iwasaki, Yoshihiro Morifuji, Toshitatsu Ogino, Takafumi Morisaki, Yutaka Nakashima, Mitsuo Katano   +8 more
openalex   +1 more source

Emerging role of non-coding RNAs in the regulation of Sonic Hedgehog signaling pathway. [PDF]

Cancer Cell Int, 2022
Ghafouri-Fard S, Khoshbakht T, Hussen BM, Taheri M, Samsami M.   +4 more
europepmc   +1 more source

Rapid and Effective Neuronal Conversion of Human Glioblastoma In Vitro and In Vivo Using Potent Small Molecules

Cell Proliferation, EarlyView.
A potent combination of small molecules YFSS (Y27632, Forskolin, SB431542, SP600125) that were screened through a neuronal‐specific promoter–reporter system TUBB3::mCherry effectively induces neuronal‐GBM conversion in vitro and in vivo, unveiling molecular mechanisms that offer a theoretical basis and a potential therapeutic strategy for treating GBM.
Ya'nan Hu, Jinming Liu, Jian Tu, Min Yang, Qisheng He, Fei Li, Xiaojing Xu, Zhongqing Ji, Jianwei Xu, Wentao Zhong, Mengwen Yan, Ying Yang, Huanxiang Zhang   +12 more
wiley   +1 more source

Cannabidiol exerts teratogenic effects on developing zebrafish through the sonic hedgehog signaling pathway. [PDF]

Sci Rep
Razmara P, Son HW, Ali DW.
europepmc   +1 more source

Hedgehog Signaling Pathway Orchestrates Human Lung Branching Morphogenesis. [PDF]

Int J Mol Sci, 2022
Belgacemi R, Danopoulos S, Deutsch G, Glass I, Dormoy V, Bellusci S, Al Alam D.   +6 more
europepmc   +1 more source

Multiple Ubiquitin-Dependent Processing Pathways Regulate Hedgehog/Gli Signaling: Implications for Cell Development and Tumorigenesis

, 2007
Lucia Di Marcotullio, Elisabetta Ferretti, Azzura Greco, Enrico De Smaele, Isabella Screpanti, Alberto Gulino   +5 more
openalex   +1 more source