PDLIM3 knockdown promotes ferroptosis in endometriosis progression via inducing Gli1 degradation and blocking Hedgehog signaling pathway. [PDF]
Liu M, Wang X, Zhu J.
europepmc +1 more source
Beyond olfaction: New insights into human odorant binding proteins
Abstract Until today, the exact function of mammalian odorant binding proteins (OBPs) remains a topic of debate. Although their main established function lacks direct evidence in human olfaction, OBPs are traditionally believed to act as odorant transporters in the olfactory sense. Now, available RNA‐seq and proteomics data identified the expression of
Mifen Chen +5 more
wiley +1 more source
Improving the integration of artificial intelligence into existing ecological inference workflows
Abstract Artificial intelligence (AI) has revolutionised the process of identifying species and individuals in audio recordings and camera trap images. However, despite developments in sensor technology, machine learning and statistical methods, a general AI‐assisted data‐to‐inference pipeline has yet to emerge. We argue that this is, in part, due to a
Amber Cowans +3 more
wiley +1 more source
Benzaldehyde stimulates autophagy via the sonic hedgehog signaling pathway in mouse brain astrocytes after treatment with Angiostrongylus cantonensis excretory-secretory products. [PDF]
Chen KY +8 more
europepmc +1 more source
Fraternal cooperation of hierarchical cancer parallels metazoan multicellularity and eusociality
ABSTRACT Metazoan multicellularity and eusociality — both outcomes of the fraternal major transitions — have numerous features in common such as uneven distribution of group‐establishing potential. In addition to this framework, I argue herein that the group‐forming principles of metazoan multicellularity and eusociality are analogous to hierarchical ...
Jibeom Choi
wiley +1 more source
Distraction force promotes the osteogenic differentiation of Gli1<sup>+</sup> cells in facial sutures via primary cilia-mediated Hedgehog signaling pathway. [PDF]
Jin M +8 more
europepmc +1 more source
Sonic Hedgehog Signaling Pathway in Amyloid Precursor Protein Trafficking and Proteolysis
Anna G. Vorobyeva +2 more
openalex +1 more source
Stromal Defense Against Cancer: An Unprecedented Mechanism Limiting Cancer Invasion Into the Bone
The roles of nonimmune systems in tumor regulation remain largely undefined. This article introduces a new concept, “stromal defense against cancer (SDAC),” which is based on recent findings that the periosteum actively responds to tumor proximity and physically impedes tumor invasion into bone.
Masayuki Tsukasaki, Hiroshi Takayanagi
wiley +1 more source
MiR-875-5p suppresses Gli1 to alter the hedgehog signaling pathway, which in turn has hepatocellular cancer-related tumor suppressing properties. [PDF]
Zhang Q, Yu M, Yang L, Sun D.
europepmc +1 more source

