Results 261 to 270 of about 834,809 (383)

Endocrine Resistance Score Based on Three Key Genes Predicts Prognosis and Reveals Potential Therapeutic Targets for ER+HER2− Breast Cancer

Cell Proliferation, EarlyView.
We generated endocrine‐resistant BC cell lines and identified CLEC3A, PCDH10, and ST3GAL1 as key endocrine‐resistant genes. More importantly, we validated their role in mediating resistance through PI3K‐AKT signalling and developed a predictive ERS with strong clinical relevance.
Liqin Ping, Lewei Zhu, Nian Chen, Xikun Liu, Jirui Zhong, Xiaoqing Sun, Hailin Tang, Kaiming Zhang   +7 more
wiley   +1 more source

Loss of Kat2b impairs intraflagellar transport and the Hedgehog signaling pathway in primary cilia. [PDF]

Sci Rep
Jun JH, Cha H, Ko JY, Kim HS, Yoo KH, Park JH.   +5 more
europepmc   +1 more source

Mechanism of Targeting the Hedgehog Signaling Pathway against Chemotherapeutic Resistance in Multiple Myeloma. [PDF]

J Oncol, 2022
Zhang Y, Yao G, Yang X, Qiu T, Wang S.
europepmc   +1 more source

High Expression of Heme Oxygenase-1 is Associated with Tumor Invasion in Gastric Cancer Through Sonic Hedgehog Signaling Pathway [PDF]

, 2013
Jie Jiang, Yali Ning, Liang Han
openalex   +1 more source

Itraconazole promotes melanoma cells apoptosis via inhibiting hedgehog signaling pathway-mediated autophagy. [PDF]

Front Pharmacol
Jin S, Liu X, Cai L, Yan J, Li L, Dong H, Gao Y, Zhu X, Zhang C, Xu X.   +9 more
europepmc   +1 more source

Anethole improves the developmental competence of porcine embryos by reducing oxidative stress via the sonic hedgehog signaling pathway. [PDF]

J Anim Sci Biotechnol, 2023
Joo YE, Jeong PS, Lee S, Jeon SB, Gwon MA, Kim MJ, Kang HG, Song BS, Kim SU, Cho SK, Sim BW.   +10 more
europepmc   +1 more source

Kdf1 Regulates Molar Cusp Morphogenesis via the PI3K/AKT/mTOR Signalling Axis

Cell Proliferation, EarlyView.
Epithelial Kdf1 knockout disrupts molar cusp morphogenesis by promoting inner enamel epithelium proliferation and invagination via PI3K/AKT/mTOR signalling. ABSTRACT Keratinocyte differentiation factor 1 (Kdf1) reportedly plays a significant role in enamel formation.
Jiayu Wang, Miao Yu, Hangbo Liu, Kai Sun, Chenxin Geng, Haochen Liu, Hailan Feng, Yang Liu, Hu Zhao, Dong Han   +9 more
wiley   +1 more source

lncRNA HHIP-AS1/HHIP modulates osteogenic differentiation of BM-MSCs by regulating Hedgehog signaling pathway. [PDF]

Aging (Albany NY), 2022
Yin XH, Wang XY, Liu SC, Yan L, He BR, Hao DJ, Yang M, Liu ZK.   +7 more
europepmc   +1 more source

Genetic Mapping of Orofacial Traits Reveals a Single Genomic Region Associated With Differences in Multiple Parameters of Jaw Size Between Astyanax mexicanus Surface and Cavefish

Evolution &Development, EarlyView.
By performing a genetic association study in cave × surface fish F2 hybrids, we discovered that premaxilla width, dentary length, and maxillary length are all significantly associated with a region on Chromosome 13 containing 109 genes. ABSTRACT The regulation of bone size is a poorly understood and complex developmental process.
Amanda K. Powers, Alleigh Amaismeier, Kathryn Thiel, William Anyonge, Suzanne E. McGaugh, Tyler E. Boggs, Clifford J. Tabin, Joshua B. Gross   +7 more
wiley   +1 more source

The Effects of Hedgehog Signaling Pathway on the Proliferation and Apoptosis of Melanoma Cells. [PDF]

J Oncol, 2022
Peng ZP, Huang SF, Li JJ, Tang XK, Wang XY, Li HM.   +5 more
europepmc   +1 more source