Results 41 to 50 of about 1,504,509 (311)
Heidelberg, ou comment une ville historique est devenue un haut lieu touristique
Mondes du Tourisme, 2012 Heidelberg traditionally stands for one of the most popular urban tourism destinations in Germany. For many tourists the city embodies the typical image of an old German university town.
Tim Freytag, Maie Gérardot
doaj +1 more source
Molecular Oncology, EarlyView.This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert +13 more
wiley +1 more source
Journal of Global Antimicrobial Resistance, 2022 : Objectives: This study aimed to sequence, assemble, and annotate three plasmids (two IncN and one IncI1) carrying the blaCTX-M-1 gene and assess their transferability rates between homologous and heterologous serovars and/or species of bacteria ...
Mackenzie Dorr +7 more
doaj +1 more source
The implications from CANGAROO-III observations of TeV blazar PKS 2155-304 [PDF]
, 2008 We have observed the high-frequency-peaked BL Lacertae object PKS2155-304 in 2004, 2005 and 2006 with the CANGAROO-III imaging atmospheric Cherenkov telescope, and have detected a signal above 660 GeV at the 4.8/sigma level during the 2006 outburst ...
Felix A. Aharonian +7 more
core +2 more sources
The impact of neutrino masses on the determination of dark energy properties
, 2006 Recently, the Heidelberg-Moscow double beta decay experiment has claimed a detection for a neutrino mass with high significance. Here we consider the impact of this measurement on the determination of the dark energy equation of state.
Bean, Rachel +3 more
core +1 more source
Jet Tomography in Heavy Ion Collisions [PDF]
, 2003 We review recent calculations of the probability that a hard parton radiates an additional energy fraction due to scattering in spatially extended matter, and we discuss their application to the suppression of leading hadron spectra in heavy ion ...
Wiedemann, Urs Achim
core +2 more sources
Epidemiology and Infection, 2019 Codex published the ‘Guidelines for Risk Analysis of Foodborne Antimicrobial Resistance’ to standardise the approach for evaluating risk posed by foodborne antimicrobial-resistant bacteria.
C. Carson +9 more
semanticscholar +1 more source
A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression
Molecular Oncology, EarlyView.Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak +8 more
wiley +1 more source
Applied and Environmental Microbiology, 2019 This study provides a deep analysis of the intrinsic stress tolerance and virulence capabilities of Salmonella Heidelberg that may have contributed to the length and severity of a recent salmonellosis outbreak.
Andrea J. Etter +6 more
semanticscholar +1 more source
Molecular Oncology, EarlyView.Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié +16 more
wiley +1 more source