Results 231 to 240 of about 150,776 (304)

Calcium oscillations in HEK293 cells lacking SOCE suggest the existence of a balanced regulation of IP₃ production and degradation. [PDF]

Front Syst Biol
Octors C, Yoast RE, Emrich SM, Trebak M, Sneyd J.   +4 more
europepmc   +1 more source

Prostate cancer diagnosis using plasma extracellular vesicles isolated via aqueous two‐phase systems

VIEW, EarlyView.
Abstract Prostate cancer (PCa) is the second most prevalent cancer in men, with early detection and precise staging remaining critical for improving outcomes. While PSA tests and biopsies are widely used, they suffer from low specificity and often lead to unnecessary procedures.
Yongmin Kwon, Minyeob Lim, Suyeon Kim, Youngju Seo, Meeyoung Kim, Jiyoul Lee, Jaesung Park   +6 more
wiley   +1 more source

Tris(1,3-dichloro-2-propyl) phosphate disrupts cellular metabolism within human embryonic kidney (HEK293) cells. [PDF]

J Hazard Mater
Avila-Barnard S, Ha M, Nemarugommula C, Wiegand JL, Ke H, De Souza A, Behar R, Volz DC.   +7 more
europepmc   +1 more source

Nanobodies as next‐generation targeting platforms: From discovery technologies to translational biomedicine

VIEW, EarlyView.
Nanobodies, derived from the variable domains of camelid heavy‐chain‐only antibodies, have emerged as transformative biomedical tools due to their nanoscale size, exceptional stability, and unique capacity to recognize cryptic epitopes. This review provides a comprehensive overview of the field, outlining the structural and biochemical features of ...
Zhenrui Ye, Xianyang Li, Meixiao Zhan
wiley   +1 more source

Sodium acetate increases the productivity of HEK293 cells expressing the ECD-Her1 protein in batch cultures: experimental results and metabolic flux analysis. [PDF]

Front Bioeng Biotechnol
Pérez-Fernández BA, Calzadilla L, Enrico Bena C, Del Giudice M, Bosia C, Boggiano T, Mulet R.   +6 more
europepmc   +1 more source

One Yeast, Sixteen Synthetic Chromosomes, Infinite Possibilities

Yeast, EarlyView.
ABSTRACT The evolution of the yeast, Saccharomyces cerevisiae, from a genetically tractable model organism to a chassis for genome‐scale engineering represents one of the most influential trajectories in eukaryotic biology. The Synthetic Yeast Genome Project (Sc2.0) embodies the current height of this trajectory, having now delivered functional ...
Edward Archer, Roy S. K. Walker, Paige E. Erpf, Ian T. Paulsen, Isak S. Pretorius   +4 more
wiley   +1 more source

Systematic comparison of rAAV vectors manufactured using large-scale suspension cultures of Sf9 and HEK293 cells. [PDF]

Mol Ther
Liu S, Li J, Peraramelli S, Luo N, Chen A, Dai M, Liu F, Yu Y, Leib RD, Li Y, Lin K, Huynh D, Li S, Ou L.   +13 more
europepmc   +1 more source

Broadening the View: Substance P and Its Metabolism in Pruritus‐Related Diseases

The Journal of Dermatology, EarlyView.
ABSTRACT Chronic pruritus is a debilitating symptom accompanying numerous inflammatory skin diseases and remains a major therapeutic challenge. Neurogenic inflammation plays a central role in its pathogenesis, with the tachykinin substance P acting as a key mediator at the interface of the nervous system, immune cells, and cutaneous tissues.
Thomas Walter, Bjoern B. Burckhardt
wiley   +1 more source