Results 1 to 10 of about 210,210 (258)

Valproic Acid as a Histone Deacetylase Inhibitor Induces ABCB1 Overexpression and De Novo ABCB5 Expression in HeLa Cells [PDF]

Current Issues in Molecular Biology
Histone deacetylase inhibitors (HDACis) induce the expression of multidrug resistance (MDR) pumps and can even display the MDR phenotype in cell lines.
Gabriela Rebeca Luna-Palencia, José Correa-Basurto, Ismael Vásquez-Moctezuma   +2 more
doaj   +2 more sources

Triacylglycerol Measurement in HeLa Cells

Bio-Protocol, 2020
Lipid droplets store triacylglycerols (triglycerides) and sterol esters to regulate lipid and energy homeostasis. Triacylglycerol measurement is often performed during the investigation of lipid droplet formation and growth.
Ximing Du, Hongyuan Yang
doaj   +4 more sources

LncRNA PCAT-1 Reduces Sensitivity of Cervical Carcinoma Cells to Cisplatin by Regulating STAT3 and PTEN Expression

Zhongliu Fangzhi Yanjiu, 2021
Objective To investigate the role and regulatory mechanism of lncRNAs PCAT-1 in the sensitivity of cervical cancer cells to DDP. Methods The expressions of PCAT-1 in human cervical cancer cell lines (HeLa and SiHa) and DDP-resistant cell lines (HeLa/DDP ...
MAO Xuebao, WANG Xiuhong
doaj   +1 more source

Design and Synthesis of Novel α-Methylchalcone Derivatives, Anti-Cervical Cancer Activity, and Reversal of Drug Resistance in HeLa/DDP Cells

Molecules, 2023
In this study, a collection of newly developed α-methylchalcone derivatives were synthesized and assessed for their inhibitory potential against human cervical cancer cell lines (HeLa, SiHa, and C33A) as well as normal human cervical epithelial cells (H8)
Zheng Yang, Zhengye Liu, Mourboul Ablise, Aikebaier Maimaiti, Aizitiaili Aihaiti, Yusupuwajimu Alimujiang   +5 more
doaj   +1 more source

Standardized Polyalthia longifolia leaf extract induces the apoptotic HeLa cells death via microRNA regulation: identification, validation, and therapeutic potential

Frontiers in Pharmacology, 2023
Polyalthia longifolia var. angustifolia Thw. (Annonaceae), is a famous traditional medicinal plant in Asia. Ample data specifies that the medicinal plant P.
Soundararajan Vijayarathna, Chern Ein Oon, Majid Al-Zahrani, Muyassar H. Abualreesh, Yeng Chen, Jagat R. Kanwar, Sumaira Sahreen, Shakira Ghazanfar, Mohd Adnan, Sreenivasan Sasidharan   +9 more
doaj   +1 more source

Pharmacological targeting transient receptor potential canonical channel 6 modulates biological behaviors for cervical cancer HeLa and SiHA cell

Cancer Cell International, 2022
Background This study aimed to observe the effect of transient receptor potential canonical channel 6 (TRPC6) antagonist 1-(β-[3-(4-method-phenyl) propoxy]-4-methoxyphenethyl)-1H-imidazole hydrate (SKF-96365) and its agonist 1-oleoyl-2-acetyl-sn-glycerol
Li-ping Bai, Ya-li Chen, Ai Zheng
doaj   +1 more source

Adriamycin-resistant cells are significantly less fit than adriamycin-sensitive cells in cervical cancer

Open Life Sciences, 2021
Adriamycin (ADR) is an important chemotherapy agent in many advanced cancers, but the emergence of drug resistance during treatment is a major limitation to its successful use.
Qi Min, Xie Lijuan, Duan Guihua
doaj   +1 more source

Leukemia-associated gene MLAA-34 reduces arsenic trioxide-induced apoptosis in HeLa cells via activation of the Wnt/β-catenin signaling pathway. [PDF]

PLoS ONE, 2017
Our laboratory previously used the SEREX method in U937 cells and identified a novel leukemia-associated gene MLAA-34, a novel splice variant of CAB39L associated with acute monocytic leukemia, that exhibited anti-apoptotic activities in U937 cells ...
Pengyu Zhang, Xuan Zhao, Wenjuan Zhang, Aili He, Bo Lei, Wanggang Zhang, Yinxia Chen   +6 more
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Confirmation of Connexin45 Underlying Weak Gap Junctional Intercellular Coupling in HeLa Cells

Biomolecules, 2020
Gap junctions (GJs) are intercellular channels that connect adjacent cells electrically and metabolically. The iodide-yellow fluorescent protein (I-YFP) gap junctional intercellular communication (GJIC) assay is a recently developed method with high ...
Eun Ju Choi, Nicolás Palacios-Prado, Juan C. Sáez, Jinu Lee   +3 more
doaj   +1 more source

Intracellular Trafficking and Distribution of Cd and InP Quantum Dots in HeLa and ML-1 Thyroid Cancer Cells

Nanomaterials, 2022
The study of the interaction of engineered nanoparticles, including quantum dots (QDs), with cellular constituents and the kinetics of their localization and transport, has provided new insights into their biological consequences in cancers and for the ...
Min Zhang, Daniel S. Kim, Rishi Patel, Qihua Wu, Kyoungtae Kim   +4 more
doaj   +1 more source