Aggregate, EarlyView.Group 14 rhodamines are one of the most widely explored fluorogenic probes with high signal‐to‐noise ratio (SNR). We have boosted the SNR of group 14 rhodamines by nano‐aggregation via a novel strategy by manipulating their dynamic physical and chemical states for the first time. The ultrahigh SNR fluorescence imaging offers a fundamental understanding
Ning Wang +5 more
wiley +1 more source
Kaempferol Targets Global Epigenetic Modifiers to Impedes Growth and Migratory Ability of HeLa Cells. [PDF]
J Cell Mol MedAfroze N, Haque S, Hussain A.
europepmc +1 more source
Multi‐Module Micro/Nanorobots for Biomedical and Environmental Remediation Applications
Advanced Intelligent Systems, EarlyView.Multi‐module microrobots (MNRs) have overcome the limitations of single‐module systems by integrating components such as propeller, actuator, manipulator, and imaging modalities. They show promise in biomedical applications, such as targeted drug delivery and tissue repair, as well as in environmental remediation, including pollutant removal.
Bairong Zhu +4 more
wiley +1 more source
Modulation of Ire1-Xbp1 Defense Pathway in Encephalomyocarditis Virus-Infected HeLa Cells. [PDF]
VirusesShishova A +5 more
europepmc +1 more source
High‐Throughput Nanorheology of Living Cells Powered by Supervised Machine Learning
Advanced Intelligent Systems, EarlyView.Herein, atomic force microscopy (AFM) and machine learning are combined to determine the viscoelastic properties of living cells at the nanoscale. A universal regressor that predicts the viscoelastic properties of mammalian cells from AFM experiments is developed. The regressor predicts the viscoelastic parameters of two cell lines.
Jaime R. Tejedor, Ricardo Garcia
wiley +1 more source
RBBP4 downregulation increases the sensitivity of A549 and HeLa cells to cisplatin by inhibiting cyclin D1 expression. [PDF]
Clinics (Sao Paulo)Zeng Z +6 more
europepmc +1 more source
Expanding the Tyrosine Kinase Domain of CSF1R? A Case Report From an Adult‐Onset Leukoencephalopathy
American Journal of Medical Genetics Part A, EarlyView.ABSTRACT Adult‐onset leukoencephalopathy with axonal spheroids and pigmented glia (ALSP), also termed hereditary diffuse leukoencephalopathy with spheroids‐1 (HDLS1), results from mutations in the CSF1R gene and leads to progressive leukoencephalopathy.
Piervito Lopriore +11 more
wiley +1 more source
Remote Control of Eukaryotic Gene Expression by a Modular Ultrasound‐Responsive RNA Toolkit
Angewandte Chemie, EarlyView.A modular RNA‐based sonogenetic toolkit enables remote control of gene expression in eukaryotes by releasing small molecule modulators from ultrasound‐responsive carriers. These modulators activate engineered mRNA elements such as riboswitches, leading to tunable protein expression.
Fahimeh Charbgoo +7 more
wiley +2 more sources
Polystyrene nanoparticles induce DNA damage and apoptosis in HeLa cells. [PDF]
HeliyonFeola A +12 more
europepmc +1 more source
Label‐Free Microscale Technologies for Isolation of Heterogeneous Circulating Tumor Cells
Advanced NanoBiomed Research, EarlyView.The isolation of circulating tumor cells (CTCs) from liquid biopsy samples is crucial for cancer treatment and monitoring. This review evaluates primary label‐free isolation methods for capturing heterogeneous CTCs and examines their potential to provide deeper insights into tumor heterogeneity and dynamics of cancer progression.
Gürhan Özkayar +5 more
wiley +1 more source