Results 121 to 130 of about 353,465 (231)

A Photoactivatable Plasma Membrane Probe Based on a Self‐Triggered Photooxidation Cascade for Live Cell Super‐Resolution Microscopy

Angewandte Chemie, EarlyView.
Herein, we establish a new photoswitching concept called self‐triggered photooxidation cascade (STPC). Rhodamine dyes have mild photosensitizing properties that enable subsequent photoactivation and photobleaching of a leuco‐rhodamine plasma membrane probe.
Sonia Pfister, Valentine Le Berruyer, Kyong Fam, Mayeul Collot   +3 more
wiley   +2 more sources

Chemical profiling and anticancer activity of Alnus incana dichloromethane fraction on HeLa cells via cell cycle arrest and apoptosis. [PDF]

BMC Complement Med Ther
Hesham W, Elzayat EM, Hosney M, Abo-Elghiet F.   +3 more
europepmc   +1 more source

Roadmap to Nanomedical Applications: Nanotoxicology and In Vitro Guidelines for Lanthanide‐Doped Luminescence Nanothermometers

Advanced NanoBiomed Research, EarlyView.
Lanthanide‐based luminescence nanothermometry holds multifaceted potential for nanomedical applications, yet despite significant research advances, clinical translation of the engineered nanomaterials is still controversial and widely disputed. This is related to crucial nanotoxicological aspects that must be addressed at the preclinical level ...
Simona Premcheska, Andre G. Skirtach, Anna M. Kaczmarek   +2 more
wiley   +1 more source

On‐Demand Ligate and Release Strategy Based on Photoclick Reaction in Tandem with Pd‐Mediated Deallylation

Angewandte Chemie, EarlyView.
A consecutive, controllable, and revertible new‐to‐nature ligation and cleavage strategy has been rationally devised to selectively visualize and manipulate biomolecules of interest. The photoclick cycloaddition between allenyl phenyl ether motifs and 9,10‐phenanthrenequinone analogues installed a terminal allyl handle at the exocyclic site, thereby ...
Boon Shing Loh, Hanqing Pang, Soh Wah Yong, Cheng Weng, Wee Han Ang   +4 more
wiley   +2 more sources

Single-cell mass spectrometry imaging of lipids in HeLa cells via tapping-mode scanning probe electrospray ionization. [PDF]

Commun Chem
Otsuka Y, Kabayama K, Miura A, Takahashi M, Hata K, Izumi Y, Bamba T, Fukase K, Toyoda M.   +8 more
europepmc   +1 more source

Myrcene: A Natural Compound Showing Anticancer Activity in HeLa Cells. [PDF]

Molecules, 2023
Pincigher L, Valenti F, Bergamini C, Prata C, Fato R, Amorati R, Jin Z, Farruggia G, Fiorentini D, Calonghi N, Zalambani C.   +10 more
europepmc   +1 more source

Recent Advances in Cancer Cell Membrane‐Based Nanoparticles and Cancer Cell‐Derived Small Extracellular Vesicles as Drug Delivery Platforms

Advanced NanoBiomed Research, EarlyView.
Cancer cell membrane‐based nanoparticles (CCM‐NPs) and cancer cell‐derived small extracellular vesicles (CsEVs) are emerging as promising drug delivery systems for targeted cancer treatment. Advances in nanotechnology have paved the way for innovative drug delivery systems that enhance the effectiveness of cancer treatment.
Wei Zhang, Jingjing Wang, Long Ngo, Li Li, Yuling Wang   +4 more
wiley   +1 more source

Spatiotemporal Super‐Resolution Imaging of Lipid Metabolism Dynamics in Physiological/Pathological Conditions

Angewandte Chemie, EarlyView.
A novel polarity‐sensitive fluorescent probe was developed for the selective targeting of lipid droplets, enabling precise visualization and quantification of lipid metabolism disorders using an integrated STED‐FLIM platform. This probe allows accurate monitoring of lipid metabolism in cellular and pathological contexts, such as atherosclerosis ...
Shixian Cao, Qihang Ding, Caixia Sun, Borbala Codogno, Zhiqiang Liu, Xiaoqiang Yu, Jong Seung Kim, Kang‐Nan Wang   +7 more
wiley   +2 more sources

D-M159 Synergistically Induces Apoptosis in HeLa Cells Through Endoplasmic Reticulum Stress and Mitochondrial Dysfunction. [PDF]

Int J Mol Sci
Li Y, Li D, Jiang Z, Yuan Z, Sun Z, Sun L.   +5 more
europepmc   +1 more source

Progress in Biomimetic Microdevices for Anticancer Drug Screening and their Potential for Enhancing In Vivo Efficacy

Advanced NanoBiomed Research, EarlyView.
Biomimetic microdevices are redefining anticancer drug screening by mimicking complex tumor microenvironments. This review highlights advances in microfluidic systems, cell microarrays, and in vivo‐like models, offering new insights into drug efficacy prediction and personalized medicine. The development of effective anticancer drugs remains a critical
Ching‐Te Kuo, Yen‐Tzu Liao, Hsinyu Lee   +2 more
wiley   +1 more source