Molecular Interplay of PARN and Telomerase: Tail Modifiers and Disease Implications
Schematic representation of the molecular interplay between PARN, telomerase‐associated, and the involvement of p53 in regulating telomere maintenance and genome stability. The top panel shows how normal PARN levels are involved in regulating p53 levels and balanced telomerase activity through their regulatory interaction with TERC and TERRA, thus ...
Sujitha Felicitus +5 more
wiley +1 more source
NS5 polymerase stimulates RNA duplex unwinding by the Orthoflavivirus NS3 helicase. [PDF]
Arnold JJ, Chib S, Cameron CE.
europepmc +1 more source
Cucumber green mottle mosaic virus: A persistent seed‐borne threat to cucurbits
Cucumber green mottle mosaic virus (CGMMV) is a highly stable, seed‐borne tobamovirus that threatens global cucurbit production. Its efficient mechanical and seed transmission, long‐term environmental persistence, and the spread of Clade II CGMMV isolates drive its rapid dissemination and cause severe yield losses.
Esperanza Gea‐Caballero +1 more
wiley +1 more source
Rare genetic diseases associated with G-quadruplex-induced replication stress. [PDF]
Herr LM +6 more
europepmc +1 more source
ABSTRACT Background There is a lack of knowledge in full‐body skin examinations (FBSEs) in the context of pathogenic or likely pathogenic variants (PV/LPV) in skin cancer predisposition genes (CPGs). This study assessed the association between carrier status of PV/LPV in skin CPGs and FBSEs and described the patterns of family letter receipt, familial ...
Jincong Q. Freeman +4 more
wiley +1 more source
Asymmetric dimeric assembly of Suv3 helicase facilitates processive RNA unwinding. [PDF]
Patra M +5 more
europepmc +1 more source
The Role of Long Noncoding RNAs in Modulation of Stress Granules in Cancer
ABSTRACT Stress granules are dynamic cellular structures that arise in response to stress. They play an important role in cancer cell survival by modulating multiple stress responses. Long noncoding RNAs (lncRNAs) have been identified as crucial regulators of stress granule (SG) dynamics, influencing cancer development and treatment resistance. LncRNAs
Nazlı Şevval Menemenli +1 more
wiley +1 more source
G-patch proteins: important regulators of pre-mRNA splicing and ribosome biogenesis. [PDF]
Karika LO +3 more
europepmc +1 more source
Decoding GUN1 in plastid‐to‐nucleus signaling: what it doesn't, what it does, and why it matters
Publication history of plant GUN1 research. Summary Plastid‐to‐nucleus retrograde signaling coordinates nuclear gene expression with the developmental and physiological state of plastids. GENOMES UNCOUPLED 1 (GUN1), a chloroplast‐localized PPR‐SMR protein, remains a central yet poorly understood component of this network.
Marco Wendler +2 more
wiley +1 more source
Functional requirement for Dicer helicase arginine methylation in 26 G siRNA biogenesis and oocyte meiotic program. [PDF]
Newkirk N +9 more
europepmc +1 more source

