Results 221 to 230 of about 194,742 (384)

Epigenetic control of cell identities from epiblast to gastrulation

open access: yesThe FEBS Journal, EarlyView.
In this review, we present and contextualize current knowledge about the roles of epigenetic modifiers during the development of mouse epiblast to gastrulation stage. The epigenetic regulation of enhancer and promoter elements by DNA methylation, histone modifications, and chromatin accessibility in concert with lineage‐specific transcription factors ...
Katrin M. Schüle, Simone Probst
wiley   +1 more source

A second maternally expressed Drosophila gene encodes a putative RNA helicase of the "DEAD box" family. [PDF]

open access: green, 1991
Tamsen de Valoir   +5 more
openalex   +1 more source

Genomic variation in DDX41 identified through clinical sequencing

open access: yes
British Journal of Haematology, EarlyView.
Celestine Wells   +11 more
wiley   +1 more source

Transcription‐coupled repair: tangled up in convoluted repair

open access: yesThe FEBS Journal, EarlyView.
In this review, we discuss recent findings derived from diverse genomic, biochemical and structural, imaging, and functional studies (B–E) that culminated in deep mechanistic insight (A) into the vital cellular process of transcription‐coupled nucleotide excision repair (TC‐NER).
Diana A. Llerena Schiffmacher   +3 more
wiley   +1 more source

Conserved function of a RasGEF‐mediated pathway in the metabolic compensation of the circadian clock

open access: yesThe FEBS Journal, EarlyView.
Metabolic compensation of the circadian clock is essential for stabilizing the period of endogenous timekeeping in environments with significant nutrient fluctuations. In this study, we demonstrate that RasGEF (SOS1)‐mediated signaling, which is influenced by metabolic conditions, supports the robust function of the circadian clock under low glucose ...
Orsolya Sárkány   +6 more
wiley   +1 more source

Human FASTK preferentially binds single‐stranded and G‐rich RNA

open access: yesThe FEBS Journal, EarlyView.
Although FASTK is known to play a role in mRNA biology, the mechanism through which it recognizes RNA has yet to be unraveled. Here, we used purified human FASTK to characterize its RNA‐binding properties in vitro. We found that FASTK prefers ssRNA oligonucleotides containing guanines with the potential to form G‐quadruplexes and binds robustly to any ...
Daria M. Dawidziak   +7 more
wiley   +1 more source

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