Results 71 to 80 of about 306,089 (345)

Armeniaspirol A: a novel anti‐Helicobacter pylori agent

Microbial Biotechnology, 2022
Summary Antibiotic resistance in Helicobacter pylori has been growing worldwide with current treatment regimens. Development of new compounds for treatment of H.
Jia Jia, Chongwen Zhang, Yaqi Liu, Yanqiang Huang, Yuefan Bai, Xudong Hang, Liping Zeng, Dongqing Zhu, Hongkai Bi   +8 more
doaj   +1 more source

bak deletion stimulates gastric epithelial proliferation and enhances Helicobacter felis-induced gastric atrophy and dysplasia in mice [PDF]

, 2015
Helicobacter infection causes a chronic superficial gastritis that in some cases progresses via atrophic gastritis to adenocarcinoma. Proapoptotic bak has been shown to regulate radiation-induced apoptosis in the stomach and colon and also susceptibility
Abuderman, A A, Burkitt, M D, Duckworth, C A, O'Reilly, L A, Pritchard, D M, Williams, J M   +5 more
core   +2 more sources

Balanced Expression of the Diiron Oxygenase BioE Is Essential for Biotin Homeostasis in Elizabethkingia meningoseptica

Advanced Science, EarlyView.
BioE is a new diiron oxygenase that catalyzes the conversion of long‐chain acyl groups into pimeloyl thioester, initiating biotin synthesis. The overexpression of EmBioE disrupts lipid metabolic homeostasis, requiring repressor BioL to maintain a balance between long‐chain fatty acids and biotin synthesis.
Meng Zhang, Ying‐ying Fu, Xiaoqiang Yang, Qiuying Qin, Xinyu Su, Jiaming Fang, Yanhua Kang, Qingwen He, Zhi Ruan, Yongchang Xu   +9 more
wiley   +1 more source

Gastric LTi cells promote lymphoid follicle formation but are limited by IRAK-M and do not alter microbial growth. [PDF]

, 2015
Lymphoid tissue inducer (LTi) cells are activated by accessory cell IL-23, and promote lymphoid tissue genesis and antibacterial peptide production by the mucosal epithelium.
Banerjee, A, Basappa, N, Blanchard, TG, Czinn, SJ, Ding, H, Drakes, ML, Fricke, WF, Kobayashi, KS, Piazuelo, MB, Shiu, J   +9 more
core   +2 more sources

Targeting DESI2 as a Novel Therapeutic Strategy for JAK2‐Mutant Leukemias

Advanced Science, EarlyView.
Mass spectrometry‐based proteomics identify DESI2 as a novel component of the JAK2‐V617F complex, which associates with and stabilizes mutant JAK2 through deSUMOylation and deubiquitination, therefore promoting JAK2 mutant cell growth and MPN disease onset in vivo.
Husheng Mei, Wuqiang Wen, Wenjun Zhang, Shujing Zhang, Ting Sun, Guiming Li, Jing Zhang, Shuang Qi, Jie Zhou, Bing Li, Yunshuo Zhao, Xiaotong Chen, Bowen Li, Yiying Xue, Wang Lu, Yanli Sun, Jingyao Wang, Hengyue Shan, Shengzhe Zhang, Yushan Huang, Yisa Chen, Wenchao Wang, Qingsong Liu, Wenchao Lu, Li Tan, Yi Ding, Jianfei Fu, Jun Long, Lei Zhang, Baobing Zhao, Aibin Liang, Baishan Jiang, Jing Yang   +32 more
wiley   +1 more source

Identification of Helicobacter pylori in Gallstone, Bile, and Other Hepatobiliary Tissues of Patients with Cholecystitis

Gut and Liver, 2010
Background/Aims: Bacterial infection is accepted as a precipitating factor in cholesterol gallstone formation, and recent studies have revealed the presence of Helicobacter species in the hepatobiliary system.
doaj   +1 more source

A novel taxon selection method, aimed at minimizing recombination, clarifies the discovery of a new sub‐population of Helicobacter pylori from Australia

Evolutionary Applications, 2020
We present a novel method for taxon selection, the aim being to minimize problems arising from highly recombinant species such as Helicobacter pylori.
Binit Lamichhane, Michael J. Wise, Eng Guan Chua, Barry J. Marshall, Chin Yen Tay   +4 more
doaj   +1 more source

Acetylation regulates the oligomerization state and activity of RNase J, the Helicobacter pylori major ribonuclease

Nature Communications, 2023
In the gastric pathogen Helicobacter pylori, post-transcriptional regulation relies strongly on the activity of the essential ribonuclease RNase J. Here, we elucidated the crystal and cryo-EM structures of RNase J and determined that it assembles into ...
Alejandro Tejada-Arranz, Aleksei Lulla, Maxime Bouilloux-Lafont, Evelyne Turlin, Xue-Yuan Pei, Thibaut Douché, Mariette Matondo, Allison H. Williams, Bertrand Raynal, Ben F. Luisi, Hilde De Reuse   +10 more
doaj   +1 more source

Impact of creatinine clearance on helicobacter pylori eradication rate in patients with peptic ulcer disease [PDF]

, 2015
Introduction. Gastrointestinal complaints are common in patients with kidney failure. The aim of this study was to investigate the effect of creatinine clearance on Helicobacter pylori (HP) eradication rate in patients with peptic ulcer disease ...
Alimadadi, M., Amirkhanlou, S., Hafezi, A.A., Homapour, S., Seyyedmajidi, M., Vafaeimanesh, J., Vakili, M.A.   +6 more
core  

The Immune Microenvironment in Liver Cancer: From Analysis to Targeting

Advanced Science, EarlyView.
This review explores how smart nanomedicines overcome the immunosuppressive tumor microenvironment in liver cancer. It details targeted delivery strategies and immune reprogramming mechanisms, including remodeling abnormal physiology, modulating metabolism, and inducing immunogenic cell death. The article highlights the paradigm shift toward multimodal
Jiaming Lan, Hao Li, Jian Xue, Yourong Duan, Jin Sun, Meng Niu   +5 more
wiley   +1 more source