Gastric Stem Cells: Physiological and Pathological Perspectives
Frontiers in Cell and Developmental Biology, 2020 Gastric epithelium operates in a hazardous environment that curtails the lifespan of the constituent cells, imposing a requirement for continuous epithelial renewal.
Shiyu Xiao +3 more
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Differential inflammatory response to Helicobacter pylori infection: etiology and clinical outcomes [PDF]
, 2015 The bacterial pathogen Helicobacter pylori commonly colonizes the human gastric mucosa during early childhood and persists throughout life. The organism has evolved multiple mechanisms for evading clearance by the immune system and, despite inducing ...
Robinson, K, White, JR, Winter, JA
core +1 more source
Frontiers in Pharmacology, 2023 Objective: Aloe-emodin (AE) is an anthraquinone compound extracted from the rhizome of the natural plant rhubarb. Initially, it was shown that AE exerts an anti-inflammatory effect. Further studies revealed its antitumor activity against various types of
Mingyang Zhu +19 more
doaj +1 more source
Multiple pathways of plasmid DNA transfer in Helicobacter pylori [PDF]
, 2012 Many Helicobacter pylori (Hp) strains carry cryptic plasmids of different size and gene content, the function of which is not well understood. A subgroup of these plasmids (e.g.
Benghezal, Mohammed +5 more
core +3 more sources
Network Pharmacology, Molecular Docking, and MR Analysis: Targets and Mechanisms of Gegen Qinlian Decoction for Helicobacter pylori [PDF]
arXiv, 2023 Objective: The study explored therapeutic targets and mechanisms of Gegen Qinlian Decoction for Helicobacter pylori infection and related gastric cancer using network pharmacology, molecular docking, and Mendelian randomization. Methods: Medicinal components of Gegen Qinlian Decoction were extracted from TCMSP and HERB databases.
arxiv
Improving efficiency of inference in clinical trials with external control data [PDF]
, 2020 Suppose we are interested in the effect of a treatment in a clinical trial. The efficiency of inference may be limited due to small sample size. However, external control data are often available from historical studies. Motivated by an application to Helicobacter pylori infection, we show how to borrow strength from such data to improve efficiency of ...
arxiv +1 more source
Oxidative Stress Resulting From Helicobacter pylori Infection Contributes to Gastric Carcinogenesis. [PDF]
, 2017 Helicobacter pylori is a gram-negative, microaerophilic bacterium that infects the stomach and can lead to, among other disorders, the development of gastric cancer. The inability of the host to clear the infection results in a chronic inflammatory state
Butcher, Lindsay D +3 more
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Diagnosis of Helicobacter pylori using AutoEncoders for the Detection of Anomalous Staining Patterns in Immunohistochemistry Images [PDF]
arXiv, 2023 This work addresses the detection of Helicobacter pylori a bacterium classified since 1994 as class 1 carcinogen to humans. By its highest specificity and sensitivity, the preferred diagnosis technique is the analysis of histological images with immunohistochemical staining, a process in which certain stained antibodies bind to antigens of the ...
arxiv
Infectious aetiology of marginal zone lymphoma and role of anti-infective therapy [PDF]
, 2016 Marginal zone lymphomas have been associated with several infectious agents covering both viral and bacterial pathogens and in some cases a clear aetiological role has been established.
Annechini, Giorgia +3 more
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Handling Noisy Labels via One-Step Abductive Multi-Target Learning and Its Application to Helicobacter Pylori Segmentation [PDF]
, 2020 Learning from noisy labels is an important concern in plenty of real-world scenarios. Various approaches for this concern first make corrections corresponding to potentially noisy-labeled instances, and then update predictive model with information of the made corrections.
arxiv +1 more source