Results 11 to 20 of about 156,187 (258)

Helicobacter pylori-Induced Persistent IGF2BP1 Activation Promotes Ferroptosis Resistance in Gastric Tumorigenesis. [PDF]

open access: yesAdv Sci (Weinh)
Helicobacter pylori infection induces sustained upregulation of the RNA‐binding protein IGF2BP1 in gastric epithelial cells, establishing a persistent epitranscriptomic program. IGF2BP1 stabilizes SLC7A11 mRNA in an m6A‐dependent manner to suppress ferroptosis and promote epithelial survival under oxidative stress. Pharmacological inhibition of IGF2BP1
Ning J   +20 more
europepmc   +2 more sources

Intrafamilial genotyping of Helicobacter pylori from faecal DNA [PDF]

open access: yes, 2011
Helicobacter pylori infection, often acquired in early childhood, is a global cause of undernutrition, gastritis, peptic ulcer disease and gastric carcinoma. This study tested the feasibility of using H.
Malcolm, C.   +22 more
core   +1 more source

Ethnic and geographic differentiation of helicobacter pylori within Iran [PDF]

open access: yes, 2010
The bacterium Helicobacter pylori colonizes the human stomach, with individual infections persisting for decades. The spread of the bacterium has been shown to reflect both ancient and recent human migrations. We have sequenced housekeeping genes from H.
Sadegh Massarrat   +45 more
core   +2 more sources

Caveolin-1 protects B6129 mice against Helicobacter pylori gastritis. [PDF]

open access: yes, 2013
Caveolin-1 (Cav1) is a scaffold protein and pathogen receptor in the mucosa of the gastrointestinal tract. Chronic infection of gastric epithelial cells by Helicobacter pylori (H. pylori) is a major risk factor for human gastric cancer (GC) where Cav1 is
Ivana Hitkova (401838)   +37 more
core   +2 more sources

Persistence of helicobacter pylori in heterotrophic drinking-water biofilms [PDF]

open access: yes, 2008
Although the route of transmission of Helicobacter pylori remains unknown, drinking water has been considered a possible transmission vector. It has been shown previously that, in water, biofilms are a protective niche for several pathogens, protecting ...
Wilks, S. A.   +9 more
core   +1 more source

Recent acquisition of Helicobacter pylori by Baka Pygmies [PDF]

open access: yes, 2013
Both anatomically modern humans and the gastric pathogen Helicobacter pylori originated in Africa, and both species have been associated for at least 100,000 years. Seven geographically distinct H.
Linz, B.   +49 more
core   +2 more sources

The sodium-dependent D-glucose transport protein of Helicobacter pylori [PDF]

open access: yes, 2008
Helicobacter pylori is a gram-negative pathogenic microaerophile with a particular tropism for the mucosal surface of the gastric epithelium. Despite its obligatory microaerophilic character, it can metabolize D-glucose and/or D-galactose in both ...
Kim E. Bettaney   +21 more
core   +1 more source

Multiple pathways of plasmid DNA transfer in Helicobacter pylori [PDF]

open access: yes, 2012
Many Helicobacter pylori (Hp) strains carry cryptic plasmids of different size and gene content, the function of which is not well understood. A subgroup of these plasmids (e.g.
Haas, Rainer   +17 more
core   +2 more sources

Comparison of omeprazole, metronidazole and clarithromycin with omeprazole/amoxicillin dual-therapy for the cure of Helicobacter pylori infection [PDF]

open access: yes, 1998
In this randomized, multicenter trial, we evaluated the effectiveness and side effect profile of a modified omeprazole-based triple therapy to cure Helicobacter pylori infection.
Miehlke, Stephan   +11 more
core   +1 more source

Age of the association between Helicobacter pylori and man [PDF]

open access: yes, 2012
When modern humans left Africa ca. 60,000 years ago (60 kya), they were already infected with Helicobacter pylori, and these bacteria have subsequently diversified in parallel with their human hosts. But how long were humans infected by H.
Linz, B.   +62 more
core   +1 more source

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