Abstract Nucleic acids are the blueprint of life. They are not only the construction plan of the single cell or higher associations of them, but also necessary for function, communication and regulation. Due to the pandemic, the attention shifted in particular to their therapeutic potential as a vaccine. As pharmaceutical oligonucleotides are unique in
Robert Minkner+3 more
wiley +1 more source
The impact of dioctyl phthalate exposure on multiple organ systems and gut microbiota in mice
Dioctyl phthalate, commonly known as bis(2-ethylhexyl) phthalate (DEHP), is a widely used plasticizer in various industries and has been shown to directly or indirectly impact human health. However, there is a lack of comprehensive studies evaluating the
Qiang Zhang+7 more
doaj
Antibiotic susceptibility, heteroresistance, and updated treatment strategies in helicobacter pylori infection [PDF]
In this review, we discuss the problem of antibiotic resistance, heteroresistance, the utility of cultures and antibiotic susceptibility tests in Helicobacter pylori (Hp) eradication, as well as the updated treatment strategies for this infection.
De Angelis, Massimiliano+3 more
core +1 more source
Multiple pathways of plasmid DNA transfer in Helicobacter pylori [PDF]
Many Helicobacter pylori (Hp) strains carry cryptic plasmids of different size and gene content, the function of which is not well understood. A subgroup of these plasmids (e.g.
Benghezal, Mohammed+5 more
core +7 more sources
A comparative study of clinicopathological features between chronic cholecystitis patients with and without Helicobacter pylori infection in gallbladder mucosa. [PDF]
BACKGROUND: Helicobacter pylori has been isolated from 10%-20% of human chronic cholecystitis specimens but the characteristics of "Helicobacter pylori positive cholecystitis" remains unclear.
Di Zhou+5 more
doaj +1 more source
Helicobacter pylori virulence factors in duodenal ulceration: A primary cause or a secondary infection causing chronicity [PDF]
Reports from countries with a high prevalence of Helicobacter pylori. (H pylori) infection do not show a proportionately high prevalence of duodenal ulceration, suggesting the possibility that H pylori cannot be a primary cause of duodenal ulceration. It
Hobsley, M, Holton, J, Tovey, FI
core +1 more source
Helicobacter pylori Membrane Vesicles Stimulate Innate Pro- and Anti-Inflammatory Responses and Induce Apoptosis in Jurkat T Cells [PDF]
Persistent Helicobacter pylori infection induces chronic inflammation in the human gastric mucosa, which is associated with development of peptic ulceration, gastric atrophy, and gastric adenocarcinoma.
Atherton+54 more
core +1 more source
The noninvasive detection technique using serum for large-scale screening is useful for the early diagnosis of gastric cancer (GC). Herein, we employed liquid chromatography mass spectrometry to determine the serum proteome signatures and related ...
Yueqing Gong+17 more
doaj +1 more source
H. pylori is a Gram-negative extracellular bacterium, first discovered by the Australian physicians Barry Marshall and Robin Warren in 1982, that colonises the human stomach mucosa.
Hong Li+9 more
doaj +1 more source
The Activity Reaction Core and Plasticity of Metabolic Networks [PDF]
Understanding the system level adaptive changes taking place in an organism in response to variations in the environment is a key issue of contemporary biology. Current modeling approaches such as the constraint-based flux balance analyses (FBA) have proved highly successful in analyzing the capabilities of cellular metabolism, including its capacity ...
arxiv +1 more source