Results 41 to 50 of about 207,971 (196)

Precise role of H pylori in duodenal ulceration [PDF]

, 2006
The facts that H pylori infection is commoner in duodenal ulcer (DU) patients than in the normal population, and that eradication results in most cases being cured, have led to the belief that it causes DU. However, early cases of DU are less likely than
Hobsley, M, Holton, J, Tovey, FI
core   +1 more source

Helicobacter pylori – 2021 [PDF]

Orvosi Hetilap, 2021
Összefoglaló. A Helicobacter pylori továbbra is a világ legelterjedtebb fertőzése: prevalenciája a fejlődő országokban 70–80%, a fejlett országokban csökkenő tendenciát mutat. A dél-magyarországi véradókban a prevalencia 32%-ra csökkent. A migráció a befogadó ország számára a fertőzés
openaire   +2 more sources

Formulation and evaluation of floating mucoadhesive alginate beads for targetingHelicobacter pylori [PDF]

, 2015
Objectives: There are various obstacles in the eradication of Helicobacter.pylori (H. pylori) infections, including low antibiotic levels and poor accessibility of the drug at the site of the infection.
Adebisi, Adebisi, Adeola O. Adebisi, Ahuja, Akiyama, Bai, Bajpai, Barbara R. Conway, Batchelor, Bazzoli, Boddupalli, Cammarota, Castro, Chun, Desai, Dunn, Dupuy, Erah, Erah, Ernst, Gal, Georgopoulos, Gåserød, Higuchi, Hixson, Iijima, Ikeda, Ishak, Kawahara, Khanvilkar, Kohri, Korsmeyer, Lee, Lehmann, Malfertheiner, Miyazaki, Moore, Murata, Murray, Najib, Nakagawa, Nayak, Norris, Park, Pasparakis, Pereira, Peter R. Laity, Peterson, Rajinikanth, Romero, Rothenbacher, Singh, Smrdel, Stops, Suerbaum, Suzuki, Umamaheshwari, Varum, Whitehead, Østberg   +59 more
core   +1 more source

Serum proteomic profiling of precancerous gastric lesions and early gastric cancer reveals signatures associated with systemic inflammatory response and metaplastic differentiation

Frontiers in Molecular Biosciences
The noninvasive detection technique using serum for large-scale screening is useful for the early diagnosis of gastric cancer (GC). Herein, we employed liquid chromatography mass spectrometry to determine the serum proteome signatures and related ...
Yueqing Gong, Yueqing Gong, Yaxin Lou, Xiurui Han, Xiurui Han, Keyan Chen, Keyan Chen, Yang Zhao, Hejun Zhang, Hejun Zhang, Jing Zhang, Jing Zhang, Ying Xiong, Ying Xiong, Weiwei Fu, Weiwei Fu, Shigang Ding, Shigang Ding   +17 more
doaj   +1 more source

Exploring the mechanism of aloe-emodin in the treatment of liver cancer through network pharmacology and cell experiments

Frontiers in Pharmacology, 2023
Objective: Aloe-emodin (AE) is an anthraquinone compound extracted from the rhizome of the natural plant rhubarb. Initially, it was shown that AE exerts an anti-inflammatory effect. Further studies revealed its antitumor activity against various types of
Mingyang Zhu, Mingyang Zhu, Qingmin He, Yanan Wang, Yanan Wang, Liying Duan, Liying Duan, Kang Rong, Kang Rong, Yingying Wu, Yingying Wu, Ye Ding, Ye Ding, Yang Mi, Yang Mi, Yang Mi, Xiaoyang Ge, Xiaocui Yang, Yong Yu, Yong Yu   +19 more
doaj   +1 more source

Functional plasticity in the type IV secretion system of Helicobacter pylori. [PDF]

, 2012
Helicobacter pylori causes clinical disease primarily in those individuals infected with a strain that carries the cytotoxin associated gene pathogenicity island (cagPAI).
Barrozo, Roberto M, Cariaga, Taryn A, Cooke, Cara L, Cover, Timothy L, Gaddy, Jennifer A, Hansen, Lori M, Johnson, Elizabeth M, Lam, Anna M, Peek, Richard M, Solnick, Jay V, Suarez, Giovanni   +10 more
core   +1 more source

The association of CagA EPIYA motifs and vacA genotypes with homologous recombination repair markers during the gastric precancerous cascade

The International Journal of Biological Markers, 2020
Background: Helicobacter pylori -induced DNA damage and impaired homologous recombination repair are vital molecular mechanisms for gastric cancer, which mainly count on its virulence factors cytotoxic-associated gene A (CagA) and vacuolating cytotoxin A
Yang Mi, Haibin Dong, Xiangdong Sun, Feifei Ren, Youcai Tang, Pengyuan Zheng   +5 more
doaj   +1 more source

Increased prevalence of precancerous changes in relatives of gastric cancer patients: critical role of H. pylori [PDF]

, 2000
Background & Aims:Helicobacter pylori is believed to predispose to gastric cancer by inducing gastric atrophy and hypochlorhydria. First-degree relatives of patients with gastric cancer have an increased risk of developing gastric cancer.
El–Nujumi, Adil, El–Omar, Emad M., Fullarton, Grant, Gillen, Derek, McColl, Kenneth E.L., Murray, Lilian S., Oien, Karin, Williams, Craig, Wirz, Angela   +8 more
core   +1 more source

Revealing the pathogenesis of gastric intestinal metaplasia based on the mucosoid air-liquid interface

Journal of Translational Medicine
Background Gastric intestinal metaplasia (GIM) is an essential precancerous lesion. Although the reversal of GIM is challenging, it potentially brings a state-to-art strategy for gastric cancer therapeutics (GC).
Simeng Liu, Huijuan Wen, Fazhan Li, Xia Xue, Xiangdong Sun, Fuhao Li, Ruoyu Hu, Huayuan Xi, Francesco Boccellato, Thomas F Meyer, Yang Mi, Pengyuan Zheng   +11 more
doaj   +1 more source

Helicobacter pylori: types of diseases, diagnosis, treatment and causes of therapeutic failure [PDF]

, 2016
Acute upper gastrointestinal lesions have a multifactorial etiology but, regardless of the cause, they are related to mucosal barrier destruction. Since Helicobacter pylori induces a superficial chronic gastritis with the infiltration of neutrophils in ...
Ciorbagiu, Mihai Calin, Mirea, Cecil Sorin, Moraru, Emil, Obleaga, Cosmin Vasile, Valcea, Ionica Daniel, Vere, Cristin Constantin   +5 more
core   +3 more sources