Results 51 to 60 of about 156,187 (258)

Modulation of Animal Gut Health by Milk Oligosaccharide

Animal Research and One Health, EarlyView.
This review summarizes the composition and structural characteristics of MOs across different mammalian species, and elucidates their roles and mechanisms in maintaining intestinal homeostasis by regulating gut microbiome and enhancing intestinal chemical, physical and immune barriers.
Ningtao Chen, Nana Jing, Shiyu Tao, Mingyue Fei, Wentao Lv, Hua Yang, Yingping Xiao, Haiqin Wu   +7 more
wiley   +1 more source

Revealing the role of metformin in gastric intestinal metaplasia treatment

Frontiers in Pharmacology
ObjectiveGastric intestinal metaplasia (IM) is a precancerous stage associated with gastric cancer. Despite the observed beneficial effects of metformin on IM, its molecular mechanism remains not fully elucidated.
Ruoyu Hu, Ruoyu Hu, Xia Xue, Xiangdong Sun, Yang Mi, Huijuan Wen, Huijuan Wen, Huayuan Xi, Huayuan Xi, Fuhao Li, Fuhao Li, Pengyuan Zheng, Pengyuan Zheng, Simeng Liu, Simeng Liu   +14 more
doaj   +1 more source

Epigenetic dynamics of Helicobacter pylori-induced COX-2 activation [PDF]

, 2009
Background and Aims: Cyclooxigenase (COX)-2 is over expressed in gastrointestinal neoplasia and Helicobacter pylori (H. pylori) infection is casually linked to gastric cancer. We undertook this study to investigate the mechanism mediating H.
Peluso, Silvia
core   +1 more source

Ferritin as a Nanoparticle Scaffold for Plant‐Produced Next‐Generation Subunit Vaccines

Biotechnology and Bioengineering, EarlyView.
ABSTRACT Protein nanoparticles offer an innovative approach to next‐generation subunit vaccine development by displaying antigenic sequences on the nanoparticle surface. Compared to traditional subunit vaccines, protein nanoparticle vaccines often show improved interaction with the immune system due to their particulate size and repetitive epitope ...
Jordan T. VanderBurgt, Richard Strasser, Christopher P. Garnham, Rima Menassa   +3 more
wiley   +1 more source

The immune microenvironment and population heterogeneity in myasthenia gravis: implications for precision therapeutics

Frontiers in Immunology
Myasthenia gravis (MG) is a chronic autoimmune disorder of the neuromuscular junction characterized by fluctuating skeletal muscle weakness. Although the pathogenic roles of autoantibodies targeting the acetylcholine receptor (AChR), muscle-specific ...
Xia Xue, Chang Liu, Chunjing Qiu, Simeng Liu, Fei Liu, Ya Li   +5 more
doaj   +1 more source

Alteration of miR-21 and miR-24 expression: biomarker for early detection of synchronous metastases in colorectal cancer: a cross-sectional study in Indonesia [PDF]

Intestinal Research
Background/Aims Timely detection with highly accurate biomarkers would be helpful in effectively managing colorectal cancer (CRC). We aim to investigate the accuracy of 3 emerging biomarkers—miR-21, miR-24, and miR-145—in detecting synchronous metastases
Yudith Annisa Ayu Rezkitha, Amal Arifi Hidayat, Irine Normalina, Ricky Indra Alfaray, Maria Inge Lusida, Takashi Matsumoto, Yoshio Yamaoka, Muhammad Miftahussurur   +7 more
doaj   +1 more source

Combinatorial Metabolic Engineering of Alkane Biosynthesis in the Osmotolerant Yeast Debaryomyces hansenii CBS 767

Biotechnology and Bioengineering, EarlyView.
ABSTRACT Debaryomyces hansenii is a yeast with diverse potential applications like producing oleochemicals from biomass. Yet, combinatorial metabolic engineering in D. hansenii is limited because, like many nonconventional organisms, key genomic data and genetic elements are missing. Here, we report phenotypic characterization, genomic integration loci,
Zekun Li, Nilesh Kumar Sharma, Sarah Weintraub, Eric Young   +3 more
wiley   +1 more source

Eradication of gastric Helicobacter Pylori : are we getting there? [PDF]

, 1995
In 1984 a curved bacillus living in the stomach of patients with gastritis and peptic ulceration was discovered and isolated. This organism named as Helicobacter Pylori (HP), has been shown to play a major role in the causation of duodenal ulcers ...
Pullicino, Edgar
core  

Survival of gastric and enterohepatic Helicobacter spp. in water: implications for transmission [PDF]

, 2008
Part of the reason for rejecting aquatic environments as possible vectors for the transmission of Helicobacter pylori has been the preference of this microorganism to inhabit the human stomach and hence use a direct oral-oral route for transmission.
Almeida, Carina, Dias, Sofia, Fernandes, I., Azevedo, N.F., Almeida, C., Azevedo, N. F., Keevil, C.W., Dias, S., Vieira, M.J., Keevil, C. W., Cerqueira, L., Vieira, M. J.   +11 more
core   +1 more source

Metal nanostructure‐coupled label‐free localized surface plasmon resonance biosensors for rapid and sensitive disease diagnosis

BMEMat, EarlyView.
LSPR biosensing enables rapid, sensitive, and low‐sample‐volume detection of biomarkers, with broad applications in diagnosing cancer, infectious, and chronic diseases. Advances in nanostructure design, micro/nanofabrication, and microfluidic integration have expanded the potential of LSPR sensors in biomedical diagnostics.
Zhaoxin Geng, Yunfei Sha, Jiongyan Yang, Hongru Yang, Xiao Liang   +4 more
wiley   +1 more source