Helicobacter pylori In Uninvestigated Dyspepsia In Primary Cares In Abakaliki, Nigeria [PDF]
There is paucity of information on the prevalence of Helicobacter pylori infection in Nigeria. Enzyme-linked immunosorbent assay (ELISA) was used to determine the prevalence of immunoglobulin G (IgG) antibodies to H.
Ugwu, Nicholas Chukwuka+1 more
core +1 more source
Bismuth-based quadruple therapy following H. Pylori eradication failures: A multicenter study in clinical practice [PDF]
Background & Aims: Helicobacter pylori (H. pylori) eradication in patients who failed one or more therapeutic attempts remains challenging. This study aimed to assess the efficacy of three-in-one capsules bismuth-based quadruple therapy (Pylera®) in ...
Zullo, Angelo+16 more
core +2 more sources
Chimeric RNA-binding protein-based killing switch targeting hepatocellular carcinoma cells
Cancer cell-specific killing switches are synthetic circuits developed as an intelligent weapon to specifically eliminate malignant cells. RNA-delivered synthetic circuits provide safer means to control oncolytic functions, in which proteolysis ...
Jiong Yang, Shigang Ding
doaj
Lipopolysaccharide Structural Differences between Western and Asian Helicobacter pylori Strains
Recent structural analysis of the lipopolysaccharide (LPS) isolated from Helicobacter pylori G27 wild-type and O-antigen ligase mutant resulted in the redefinition of the core-oligosaccharide and O-antigen domains.
Hong Li+5 more
doaj +1 more source
Efficient Degradation and Expression Prioritization with Small RNAs [PDF]
We build a simple model for feedback systems involving small RNA (sRNA) molecules based on the iron metabolism system in the bacterium E. coli, and compare it with the corresponding system in H. pylori which uses purely transcriptional regulation. This reveals several unique features of sRNA based regulation that could be exploited by cells.
arxiv +1 more source
Treatment of helicobacter pylori infection in atrophic gastritis [PDF]
Helicobacter pylori (Hp) is a major human pathogen causing chronic, progressive gastric mucosal damage and is linked to gastric atrophy and cancer. Hp-positive individuals constitute the major reservoir for transmission of infection.
Annibale, B, Carabotti, M, Lahner, E
core +1 more source
Gut microbiota and its therapeutic implications in tumor microenvironment interactions
The development of cancer is not just the growth and proliferation of a single transformed cell, but its tumor microenvironment (TME) also coevolves with it, which is primarily involved in tumor initiation, development, metastasis, and therapeutic ...
Pengya Feng+14 more
doaj +1 more source
Prevalence of Helicobacter pylori in patients with gastro-oesophageal reflux disease : systematic review. [PDF]
Objectives: To ascertain the prevalence of Helicobacter pylori in patients with gastro-oesophageal reflux disease and its association with the disease.
Childs, S.+3 more
core +2 more sources
Diagnostic strategy of irritable bowel syndrome: a low- and middle-income country perspective [PDF]
Irritable bowel syndrome (IBS) is a highly prevalent gastrointestinal disorder associated with substantial impairment which considerably burdens healthcare systems worldwide.
Amal Arifi Hidayat+6 more
doaj +1 more source
Helicobacter suis infection alters glycosylation and decreases the pathogen growth inhibiting effect and binding avidity of gastric mucins [PDF]
Helicobacter suis is the most prevalent non-Helicobacter pylori Helicobacter species in the human stomach and is associated with chronic gastritis, peptic ulcer disease, and gastric mucosa-associated lymphoid tissue (MALT) lymphoma. H. suis colonizes the
Adamczyk, Barbara+11 more
core +1 more source