Results 211 to 220 of about 130,724 (273)

Single‐cell RNA sequencing revealed the T‐cell heterogeneity and exhaustion subsets of Helicobacter pylori‐induced gastritis‐to‐cancer transformation

VIEW, Volume 7, Issue 1, February 2026.
H. pylori infection is a major cause of stomach cancer, but its effect on immune cells in tumors is unclear. Using single‐cell sequencing, we mapped the stomach tumor environment and discovered a specific exhausted T‐cell subtype, marked by the FYB1 gene, that is abundant in H. pylori‐positive tumors and linked to patient prognosis. Our findings reveal
Yanhui Yang, Yanxia Liu, Xiaole Guo, Zhaorun Li, Ziyu Liu, Shuming Zhang, Yuma Yang, Jun Liu, Shoucheng Ma, Linke Ma, Xianmei Chen, Xue Li, Yuanyuan Tang, Xiaoling Ding, Xiaofei Li, Qian Hao, Yanjie You, Tingting Yang, Qingrui Li, Xue Zhang, Sihan Zhang, Hengjun Gao, Shengjuan Hu   +22 more
wiley   +1 more source

Association of dietary fiber intake with Helicobacter pylori infection and all-cause mortality among US population. [PDF]

BMC Nutr
Zhang R, Ye S.
europepmc   +1 more source

Chinese Guidelines for Diagnosis and Treatment of Chronic Rhinosinusitis (2024)

World Journal of Otorhinolaryngology - Head and Neck Surgery, Volume 12, Issue 1, Page 25-55, February 2026.
ABSTRACT Chronic rhinosinusitis (CRS), a complex inflammatory disease with heterogeneous pathogenesis, demands evolving evidence‐based strategies. Since the 2018 Chinese guidelines and EPOS2020, international advances in CRS immunopathology and biologics have revolutionized therapeutic approaches, particularly through phenotype–endotype classification ...
Subspecialty Group of Rhinology, Editorial Board of Chinese Journal of Otorhinolaryngology Head and Neck Surgery, Subspecialty Group of Rhinology, Society of Otorhinolaryngology Head and Neck Surgery, Chinese Medical Association   +4 more
wiley   +1 more source

Association between Helicobacter pylori infection and hospital-acquired upper gastrointestinal bleeding: a prospective case-control study. [PDF]

BMC Gastroenterol
Piwchan S, Sripariwuth E, Chuensakul S.
europepmc   +1 more source

A Scalable Organoid Model of Urothelial Aging for Metabolic Interrogation, Infection Modeling, and Reversal of Age‐Associated Changes

Aging Cell, Volume 25, Issue 2, February 2026.
mBEDOs: a scalable platform for modeling urothelial aging. mBEDOs derived from aged mouse bladders capture essential molecular and cellular features of urothelial aging and provide a versatile system for high‐throughput metabolic profiling, therapeutic screening via metabolite supplementation, age‐ and sex‐based analyses, infection modeling, and immune–
Adwaita R. Parab, Arnold M. Salazar, Steven J. Bark, Margarita Divenko, Vasanta Putluri, D'Feau J. Lieu, Aadya S. Singh, Nagireddy Putluri, Indira U. Mysorekar   +8 more
wiley   +1 more source

Treatment and Follow-Up of Patients With Helicobacter pylori Infection in Primary Health Care: A Retrospective Multicenter Study. [PDF]

Cureus
Pais Neto C, Soares Alves M, Ferreira M, Veloso Magalhães R, Guimarães S.   +4 more
europepmc   +1 more source

Bacterial Toxin Exploits Host Membrane Phospholipid as a Receptor for Binding, Entry, and Cytopathogenicity

Molecular Microbiology, Volume 125, Issue 2, Page 145-158, February 2026.
Mycoplasma pneumoniae pathogenesis relies on its CARDS toxin, which initiates cell binding and subsequent uptake by exploiting sphingomyelin, a key phospholipid found in the host plasma membrane. Maximal cellular entry and full cytotoxic effects are achieved through a synergistic mechanism that involves interaction with the protein coreceptor annexin ...
Alejandra M. Kirkpatrick, Thirumalai R. Kannan   +1 more
wiley   +1 more source

Association between helicobacter pylori infection and abdominal aortic aneurysm: a systematic review and meta-analysis. [PDF]

BMC Cardiovasc Disord
Arain M, Karnatapu J, Moradi I, Cevallos LB, Ravi PC, Valluri P, Lubana A, Maryam A, Moradi A, Yennam AK, Avinash BNVLSV, Mian ZR, Syed S, Rahnama BS, Ahmed KAHM, Shafique MA.   +15 more
europepmc   +1 more source

Antireflux Surgery for Barrett's Esophagus: Where Do We Stand in Preventing Esophageal Adenocarcinoma?

Annals of the New York Academy of Sciences, Volume 1556, Issue 1, February 2026.
Esophageal adenocarcinoma (EAC) often develops from gastroesophageal reflux disease (GERD), with Barrett's esophagus (BE) as its main precursor. While proton pump inhibitors manage GERD symptoms, their preventive role in EAC remains unclear. This review summarizes advances in diagnosing BE and evaluates anti‐reflux surgery for its potential to prevent ...
Dagmar Kollmann, Cansel Etyemez, Reza Asari, Gerd Jomrich, George Triadafilopoulos, Kenneth J. Vega, Bruno Zilberstein, Margaret J. Zhou, Qin Huang, Hiroshi Mashimo, Eun Ji Shin, John O. Clark, Sebastian F. Schoppmann   +12 more
wiley   +1 more source

Helicobacter pylori infection might be a protective factor against Parkinson's disease. [PDF]

Sci Rep
Xiao X, Wang Z, Zhang H, Li B, Hou Q, Wang J, Xiu W, Zhang R, Zhang G, Lan Y, Chen Y, Zhang M, Sun C, Gao Y, Li A, Zhu X, Gao C, He C, Lu F, Shuai P.   +19 more
europepmc   +1 more source