N3A motifs in RIβ mediate allosteric crosstalk between cAMP and ATP in PKA activation. [PDF]
Wu J +6 more
europepmc +1 more source
ML Workflows for Screening Degradation‐Relevant Properties of Forever Chemicals
The environmental persistence of per‐ and polyfluoroalkyl substances (PFAS) necessitates efficient remediation strategies. This study presents physics‐informed machine learning workflows that accurately predict critical degradation properties, including bond dissociation energies and polarizability.
Pranoy Ray +3 more
wiley +1 more source
Bridge helix of Cas12a is an allosteric regulator of R-loop formation and RuvC activation. [PDF]
Ganguly C +6 more
europepmc +1 more source
An IgH Enhancer That Drives Transcription through Basic Helix-Loop-Helix and Oct Transcription Factor Binding Motifs [PDF]
Christopher C. Cioffi +5 more
openaire +1 more source
Ion‐Pair‐Tuned Ionogels for Broad‐Range Linear Pressure Sensing
Ionogels engineered through ion‐pair tuning extend the linear sensing range of capacitive pressure sensors. By balancing ionic mobility and polarizability within the polymer matrix, this approach mitigates dielectric saturation and maintains a stable pressure response across a broad operating range.
Hyeonseo Joo +11 more
wiley +1 more source
Genome-Wide Identification and Evolutionary Analysis of the bHLH Transcription Factor Family in Rosa roxburghii. [PDF]
Li YY, Ling LZ, Zhang SD.
europepmc +1 more source
Harnessing Phase Separation for the Development of High‐Performance Hydrogels
ABSTRACT Hydrogels are indispensable for the development of next‐generation bioelectronics, soft robotics, and biomedical devices, where their mechanical properties determine performance and reliability. Among strategies to enhance hydrogel mechanics, phase separation enables controlled heterogeneity resulting in gel networks that are reinforced by ...
Yue Shao +3 more
wiley +1 more source
Rabies lyssavirus phosphoprotein possesses RNA duplex-unwinding activities. [PDF]
Mu J +7 more
europepmc +1 more source
Post‐Translational Regulation of CD8+ T Cell Fate and Dysfunction in Tumor Immunity
This review delineates how post‐translational modifications (PTMs) function as a central regulatory interface governing CD8+ T cell activation, differentiation, persistence, and exhaustion in antitumor immunity. By integrating antigenic, metabolic, and microenvironmental cues, diverse PTM programs coordinate transcriptional and chromatin states that ...
Zihao Zhou +8 more
wiley +1 more source
Identification of Transcription Factors of <i>GmHPL</i> Involved in Modulating Pathogen Stresses in Soybean. [PDF]
Wang Y +7 more
europepmc +1 more source

