Results 161 to 170 of about 53,124 (263)

Microfluidic Mixing with the Dynamic Control of Magnetic Actuation

Advanced Intelligent Systems, EarlyView.
Schematic illustration and flow field visualization of magnetically actuated L‐shaped microrobots displaying cooperative vortex generation for enhanced microscale mixing. The left side shows the electromagnetic actuation setup, which enables programmable control of rotational direction and frequency.
Prashant Kishor Sharma, Tsung‐Yen Lu, Chia‐Yuan Chen   +2 more
wiley   +1 more source

The Role of Chemistry Across Disciplines From Humanities to Life Sciences in Understanding Complexity and Emergence

Angewandte Chemie, EarlyView.
This study explores the origins of life by linking prebiotic chemistry, the emergence of information‐carrying molecules such as RNA and proteins, and philosophical questions about consciousness. The study emphasizes the role of molecular evolution in the Central Dogma and provides insights into the chemical origins of biology and the basis of life's ...
Harald Schwalbe, Josef Wachtveitl, Alexander Heckel, Florian Buhr, Sabrina Toews, Thomas M. Schimmer   +5 more
wiley   +2 more sources

Structures of nucleotide-bound human telomerase at several steps of its telomeric DNA repeat addition cycle. [PDF]

Nat Commun
Balch S, Franco-Echevarría E, Ghanim GE, Kretsch RC, Das R, Nguyen THD.   +5 more
europepmc   +1 more source

Adaptive Autonomy in Microrobot Motion Control via Deep Reinforcement Learning and Path Planning Synergy

Advanced Intelligent Systems, EarlyView.
This study introduces a data‐driven framework that combines deep reinforcement learning with classical path planning to achieve adaptive microrobot navigation. By training a surrogate neural network to emulate microrobot dynamics, the approach improves learning efficiency, reduces training time, and enables robust real‐time obstacle avoidance in ...
Amar Salehi, Bairong Zhu, Haoyu Liu, Tingting Yu   +3 more
wiley   +1 more source

Modular Assembly of Dynamic Polymer Networks From Heteroaffinity Cross‐Links to Multivalent Proteins

Angewandte Chemie, EarlyView.
This study develops a method to modularly assemble oligomeric binding proteins, like streptavidin, using heterobifunctional cross‐linkers that have both a strong‐ and a weak‐affinity binding moiety. These dynamic cross‐linkers enable the assembly of polymer networks with unique meta‐stable nonequilibrium topologies, and that exhibit chemically tunable ...
Tianyue Dai, Yuntao Qiu, Katherine M. Leon Hernandez, Wesley Chan, Katrina Mejia, Natalia Nemeria, Colin D. Kinz‐Thompson   +6 more
wiley   +2 more sources

Artificial Intelligence for Multiscale Modeling in Solid‐State Physics and Chemistry: A Comprehensive Review

Advanced Intelligent Systems, EarlyView.
This review explores the transformative impact of artificial intelligence on multiscale modeling in materials research. It highlights advancements such as machine learning force fields and graph neural networks, which enhance predictive capabilities while reducing computational costs in various applications.
Artem Maevskiy, Vitalii Kapitan, Andrey Ustyuzhanin   +2 more
wiley   +1 more source

BHLHE22, targeted by deubiquitinating enzyme OTUD3, exerts an antitumor role in triple-negative breast cancer progression via transcriptionally inhibiting CDT1. [PDF]

Breast Cancer Res
Jiang L, Xu J, Jiang C, Jia Y, Zhang Y, Sun T.   +5 more
europepmc   +1 more source

Worm‐Inspired Soft Robots With Modular Outfit‐Changing for Intelligent Multienvironment Adaptation

Advanced Intelligent Systems, EarlyView.
This study proposes a worm‐inspired soft robot capable of locomotion across multiple environments through a modular “outfit‐changing” strategy. The robot integrates pneumatically actuated peristaltic segments with interchangeable external modules, enabling efficient motion on ground surfaces, within pipelines, through granular media, and underwater ...
Xiaomin Liu, Heng Wei, Zhengxin Guo, Zheng Liu, Yi Jin, Yunwei Zhao, Changyong Chase Cao   +6 more
wiley   +1 more source

Structural insights and biophysical characterization of p90RSK2:ERK2 complex. [PDF]

Biochem J
Kobori EK, Nguyen HPM, Wu J, Chen K, Malinovski R, Taylor S.   +5 more
europepmc   +1 more source

An evolutionarily conserved salt bridge stabilizes the active site for GTP hydrolysis in Rho GTPases. [PDF]

J Biol Chem
Marcus K, Schwabe M, Knihtila R, Mattos C.   +3 more
europepmc   +1 more source