Results 181 to 190 of about 53,124 (263)

Optimization of CEST MRI Reporter Protein Design Using Cation‐Pi Networks

Chemistry – A European Journal, EarlyView.
A novel engineering approach can produce reporter proteins for cell and viral therapy tracking with unique magnetic resonance imaging (MRI) signatures, detectable with chemical exchange saturation transfer (CEST). We discover how cation‐π interactions between amino acid groups can help us fine‐tune magnetic resonance properties for noninvasive ...
David E. Korenchan, Ethan J. French, Emerenziana Runco, Chetan B. Dhakan, Jinwu Yan, Hiroshi Nakashima, Michael T. McMahon, Assaf A. Gilad, Christian T. Farrar   +8 more
wiley   +1 more source

Structural bases of signal generation and transduction by the SPS amino acid sensor of Saccharomyces cerevisiae. [PDF]

G3 (Bethesda)
Scharff-Poulsen P, Kielland-Brandt MC.
europepmc   +1 more source

Controlling Aggregation‐Induced Emission by Sterics in Nitrogen–Boron–Nitrogen (NBN)‐Doped Tetraphenylethylene‐Like Molecular Propellers

Chemistry – A European Journal, EarlyView.
Nitrogen–boron–nitrogen (NBN)‐substituted molecular propellers are presented as structural framework for aggregation induced emission (AIE) applications. Steric hindrance is revealed to steer maximum‐AIE behavior, leading to refined control over assembly‐induced luminescence.
Nico Groß, Bojan Tanović, Frank Hampel, Henry Dube, Ani Ozcelik   +4 more
wiley   +1 more source

Interactive Role of the DHPR β_1a SH3 Domain in Skeletal Muscle Excitation-Contraction Coupling. [PDF]

Biomolecules
Karunasekara Y, Aditya S, Norris NC, Cappello J, Dulhunty AF, Board PG, Eltit JM, Perez CF, Casarotto MG.   +8 more
europepmc   +1 more source

Porphyrin‐Geländer–Helical Conjugated Banister Type Porphyrin Dyads

Chemistry – A European Journal, EarlyView.
Porphyrin arrays go chiral–A porphyrin Geländer macrocycle represents the intriguing prototype architecture of helically chiral butadiyne‐linked porphyrin arrays. This study combines synthetic, spectroscopic, and computational methods to shed light on its structure, chiroptical properties, and tunability, highlighting its promise for advancing ...
Joël F. Keller, Adriano D'Addio, Marcel Mayor   +2 more
wiley   +1 more source

Genome-Wide Identification and Characterization of the Trihelix Transcription Factor Family in <i>Pinus massoniana</i> and Gene Expression Patterns Analysis. [PDF]

Plants (Basel)
Liu P, Wang D, Xu S, Sun S, Yang M, Chen M, Ji K.   +6 more
europepmc   +1 more source

Recent Advances in Chemical Probing Strategies for RNA Structure Determination in Vivo

Chemistry – A European Journal, EarlyView.
This Review illustrates how structural probes combined with advanced sequencing technologies are revolutionizing our ability to map RNA structures and interactions within living cells. It highlights the development of innovative strategies tailored to probe RNA structures in particular biological contexts.
Maryana Yarshova, Jieyu Zhao, Chun Kit Kwok   +2 more
wiley   +1 more source

Structural characterization of metal binding in human tyrosylprotein sulfotransferase 2, TPST2. [PDF]

Sci Rep
Jin M, Noh C, Yang J, Kim H, Park SB, Kim YC, Eom SH.   +6 more
europepmc   +1 more source

Highly Potent Fluorogenic Ligands for Triplex DNA: 5‐Substituted 2‐(Naphthalen‐2‐yl)‐4H‐Chromen‐4‐Ones

Chemistry – A European Journal, EarlyView.
5‐Substituted 2‐(naphthalen‐2‐yl)‐4H‐chromen‐4‐ones are reported as a novel class of highly potent and selective triplex DNA ligands. These ligands induce triplex formation at submicromolar concentrations and inhibit enzymatic activity via ligand‐mediated triplex formation.
Nghia Tran, Landy Gu, Krege M. Christison, Kalee Thao, Liang Xue   +4 more
wiley   +1 more source

Host switching mutations in H5N1 influenza hemagglutinin suppress site-specific activation dynamics. [PDF]

Nat Commun
Kephart SM, Awatramani KF, Saunders MI, Croft JT, Lee KK.   +4 more
europepmc   +1 more source