Results 21 to 30 of about 53,124 (263)

A splicing variant of TFEB negatively regulates the TFEB-autophagy pathway

Scientific Reports, 2021
Transcription factor EB (TFEB) is a master regulator of the autophagy-lysosomal pathway (ALP). Here, we cloned a novel splicing variant of TFEB, comprising 281 amino acids (hereafter referred to as small TFEB), and lacking the helix-loop-helix (HLH) and ...
Jee-Yun Park, Hee-Young Sohn, Young Ho Koh, Chulman Jo   +3 more
doaj   +1 more source

Global identification, structural analysis and expression characterization of bHLH transcription factors in wheat

BMC Plant Biology, 2017
Background Basic helix-loop-helix (bHLH) transcription factors (TFs), which are widely distributed in eukaryotic organisms, play crucial roles in plant development. However, no comprehensive analysis of the bHLH family in wheat (Triticum aestivum L.) has
Xiao-Jiang Guo, Ji-Rui Wang
doaj   +1 more source

Genome-wide identification and expression analysis of the bHLH transcription factor family and its response to abiotic stress in sorghum [Sorghum bicolor (L.) Moench]

BMC Genomics, 2021
Background Basic helix-loop-helix (bHLH) is a superfamily of transcription factors that is widely found in plants and animals, and is the second largest transcription factor family in eukaryotes after MYB.
Yu Fan, Hao Yang, Dili Lai, Ailing He, Guoxing Xue, Liang Feng, Long Chen, Xiao-bin Cheng, Jingjun Ruan, Jun Yan, Jianping Cheng   +10 more
doaj   +1 more source

Dimerization through the Helix-Loop-Helix Motif Enhances Phosphorylation of the Transcription Activation Domains of Myogenin [PDF]

Molecular and Cellular Biology, 1994
The muscle-specific basic helix-loop-helix (bHLH) protein myogenin activates muscle transcription by binding to target sequences in muscle-specific promoters and enhancers as a heterodimer with ubiquitous bHLH proteins, such as the E2A gene products E12 and E47.
J, Zhou, E N, Olson
openaire   +2 more sources

Evidence for the Rapid and Divergent Evolution of Mycoplasmas: Structural and Phylogenetic Analysis of Enolases

Frontiers in Molecular Biosciences, 2022
Mycoplasmas are a group of prokaryotes without cell walls that have evolved through several rounds of degenerative evolution. With a low cell DNA G + C content and definitively long genetic lineages, mycoplasmas are thought to be in a state of rapid ...
Rong Chen, Rong Chen, Lin Zhao, Lin Zhao, Rong Gan, Zhixin Feng, Chenxi Cui, Xing Xie, Fei Hao, Zhenzhen Zhang, Li Wang, Tingting Ran, Weiwu Wang, Shuijun Zhang, Yufeng Li, Wei Zhang, Maoda Pang, Qiyan Xiong, Qiyan Xiong, Guoqing Shao, Guoqing Shao   +20 more
doaj   +1 more source

Solution structure of a phytocystatin from Ananas comosus and its molecular interaction with papain. [PDF]

PLoS ONE, 2012
The structure of a recombinant pineapple cystatin (AcCYS) was determined by NMR with the RMSD of backbone and heavy atoms of twenty lowest energy structures of 0.56 and 1.11 Å, respectively.
Deli Irene, Tse-Yu Chung, Bo-Jiun Chen, Ting-Hang Liu, Feng-Yin Li, Jason T C Tzen, Cheng-I Wang, Chia-Lin Chyan   +7 more
doaj   +1 more source

Characterization of Phytochrome-Interacting Factor Genes in Pepper and Functional Analysis of CaPIF8 in Cold and Salt Stress

Frontiers in Plant Science, 2021
As a subfamily of basic helix-loop-helix (bHLH) transcription factors, phytochrome-interacting factors (PIFs) participate in regulating light-dependent growth and development of plants. However, limited information is available about PIFs in pepper.
Youxin Yang, Yelan Guang, Feng Wang, Yue Chen, Wenting Yang, Xufeng Xiao, Sha Luo, Yong Zhou, Yong Zhou   +8 more
doaj   +1 more source

Calcium-Binding Proteins with Disordered Structure and Their Role in Secretion, Storage, and Cellular Signaling

Biomolecules, 2018
Calcium is one of the most important second messengers and its intracellular signaling regulates many aspects of cell physiology. Calcium ions, like phosphate ions, are highly charged and thus are able to alter protein conformation upon binding; thereby ...
Ewa A. Grzybowska
doaj   +1 more source

Role of water-bridged interactions in metal ion coupled protein allostery.

PLoS Computational Biology, 2022
Allosteric communication between distant parts of proteins controls many cellular functions, in which metal ions are widely utilized as effectors to trigger the allosteric cascade.
Xingyue Guan, Cheng Tan, Wenfei Li, Wei Wang, D Thirumalai   +4 more
doaj   +1 more source

TFE3: a helix-loop-helix protein that activates transcription through the immunoglobulin enhancer muE3 motif. [PDF]

Genes & Development, 1990
The muE3 motif within the immunoglobulin heavy-chain enhancer is required for full enhancer activity and is known to bind one, or perhaps a family, of related ubiquitous nuclear proteins. Here, we present the isolation of a cDNA that encodes an apparently novel microE3-binding protein designated TFE3. The major open reading frame of the cDNA predicts a
H, Beckmann, L K, Su, T, Kadesch
openaire   +2 more sources