Results 241 to 250 of about 452,289 (289)

Helix-helix packing angle preferences for finite helix axes

Proteins: Structure, Function, and Genetics, 1998
Recently, James Bowie addressed the question of how to normalize correctly the distribution of observed helix-helix packing angles in proteins (Bowie, Nature Struct. Biol. 4:915-917, 1997). A hitherto unrealized yet significant bias toward crossed packing angles was revealed. However, the derived random reference distribution of packing angles requires
D, Walther, C, Springer, F E, Cohen
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Helix to helix packing in proteins

Journal of Molecular Biology, 1981
Abstract Analysis of the pattern of residue to residue contacts at the interface of 50 helix to helix packings observed in ten proteins of known structure supports a model for helix to helix packing in which the ridges and grooves on the helix surface intercalate.
C, Chothia, M, Levitt, D, Richardson
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Helix–helix interfaces and ligand binding

Journal of Theoretical Biology, 2011
Helix-helix parallel interfaces can be characterized by certain combinations of amino acids, which repeatedly occur at core positions a and d (leucine zipper nomenclature) in homologous and nonhomologous proteins and influence interhelical angles. Applied for the prediction of interhelical angles in glutathione S-transferase, intracellular chloride ...
Natalya, Kurochkina, Tsering, Choekyi
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The linker of calmodulin — to helix or not to helix

Cell Calcium, 1992
The linker regions of the central helices of calmodulin and of troponin C are observed to be alpha-helices in crystal and in solution. However, these linkers are predicted to be non-helical by standard algorithms. Further, there is strong evidence that when calmodulin interacts with some of its targets this linker helix bends.
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Helix Theory

Moscow Mathematical Journal, 2004
The aim of this expository paper is to give a wide overview of helix theory, with a special focus on projective spaces and del Pezzo surfaces. The authors first introduce the concepts of exceptional collections, mutations, helices, orthogonal decompositions, braid group action and Serre operator in the context of a linear triangulated category ...
Gorodentsev, A., Kuleshov, S.
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Helix Health

Personalized Medicine, 2008
Helix Health PLLC is the first privately funded medical practice in the USA to combine genetic and genomic expertise with comprehensive risk assessment for all genetic and common chronic diseases. The company's goal is to introduce genetic and genomic healthcare to the mainstream.
Sarah, Coombes, Steven Ar, Murphy
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The Helix-Loop-Helix Motif

1992
Recently, families of transcription factors have been identified, having in common a region of homology in their DNA binding domain. Examples are DNA binding proteins containing zinc fingers, homeo-boxes, leucine zippers, etc. In this review I will discuss the structure and function of a new class of proteins that contain a region of homology in their ...
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Helix-helix packing in a membrane-like environment

Journal of Molecular Biology, 1997
The unique ability of the glycophorin A transmembrane helix to dimerize in SDS has previously been exploited in studies of the sequence specificity of helix-helix packing in a micellar environment. Here, we have made different insertion mutants in the critical helix-helix interface segment, and find that efficient dimerization can be mediated by a ...
I, Mingarro, A, Elofsson, G, von Heijne
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Rop/Helix-loop-helix similarity

DNA Sequence, 1991
T J, Gibson, P R, Sibbald, P, Rice
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Triple-helix polysaccharides: Formation mechanisms and analytical methods

Carbohydrate Polymers, 2021
Steve Cui, Qingbin Guo
exaly