Results 51 to 60 of about 105,962 (297)

The parasitic worm product ES-62 up-regulates IL-22 production by γδ T cells in the murine model of Collagen-Induced Arthritis [PDF]

, 2014
S-62 is a phosphorylcholine (PC)-containing glycoprotein secreted by the filarial nematode Acanthocheilonema viteae that acts to modulate the host immune response to promote the establishment of chronic helminth infection.
Harnett, Margaret, Harnett, William, Pineda, Miguel Angel   +2 more
core   +1 more source

Long‐term trends in parasite diversity and infection levels: approaches and patterns

Biological Reviews, EarlyView.
ABSTRACT Parasites exist in every ecosystem, affecting nearly all organisms and playing a complex role in human societies. On the one hand, they contribute substantially to biodiversity and support ecosystem stability by performing essential ecological functions.
Cyril Hammoud, Juan Antonio Balbuena, Isabel Blasco‐Costa, Katie O'Dwyer, Rachel A. Paterson, Tomáš Scholz, Christian Selbach, Bernd Sures, David W. Thieltges   +8 more
wiley   +1 more source

Binding and cleavage of pro-urokinase by a tegument extract of Fasciola hepatica newly excysted juveniles activate the host fibrinolytic system

Veterinary Research
Plasmin, the final product of fibrinolysis, is a broad-spectrum serine protease that degrades extracellular matrix (ECM) components, a function exploited by multiple pathogens for dissemination purposes.
Judit Serrat, María Torres-Valle, Carolina De Marco Verissimo, Mar Siles-Lucas, Javier González-Miguel   +4 more
doaj   +1 more source

The extent, nature, and pathogenic consequences of helminth polyparasitism in humans: A meta-analysis.

PLoS Neglected Tropical Diseases, 2019
BackgroundIndividual helminth infections are ubiquitous in the tropics; geographical overlaps in endemicity and epidemiological reports suggest areas endemic for multiple helminthiases are also burdened with high prevalences of intestinal protozoan ...
Rose E Donohue, Zoë K Cross, Edwin Michael   +2 more
doaj   +1 more source

Enteric helminths promote Salmonella co-infection by altering the intestinal metabolome [PDF]

, 2017
Intestinal helminth infections occur pre dominantly in regions where exposure to enteric bacterial pathogens is also common. Helminth infections inhibit host immunity against microbial pathogens, which has largely been attributed to the induction of ...
Borchers, Christoph H., Brosschot, Tara P., Brown, Eric M., Finlay, B. Brett, Gill, Navkiran, Han, Jun, Marshall, Natalie C., Perona-Wright, Georgia, Redpath, Stephen A., Reynolds, Lisa A., Valdez, Yanet, van der Heijden, Joris, Woodward, Sarah E., Yurist-Doutsch, Sophie   +13 more
core   +1 more source

Volumetric MRI study of the brain in patients with neurocysticercosis and mesial temporal lobe epilepsy

Epileptic Disorders, EarlyView.
Abstract Objective Neurocysticercosis (NCC) is a common parasitic infection of the central nervous system and a known cause of focal epilepsy. Its potential role in triggering or contributing to mesial temporal lobe epilepsy with hippocampal sclerosis (MTLE‐HS) is suggested, but the impact on brain volumetry remains unclear.
Jaisa Quedi Araújo, Bruna da Silveira Arruda, Sandra Polita, Maurício Anés, Thiago Junqueira Ribeiro de Rezende, Matheus de Lima Ruffini, Adolfo Moraes de Souza, Jordana Soares Chaves, Fabiano Reis, Marino Muxfeldt Bianchin, Juliana Ávila Duarte   +10 more
wiley   +1 more source

Glyco-Engineering Plants to Produce Helminth Glycoproteins as Prospective Biopharmaceuticals: Recent Advances, Challenges and Future Prospects

Frontiers in Plant Science, 2022
Glycoproteins are the dominant category among approved biopharmaceuticals, indicating their importance as therapeutic proteins. Glycoproteins are decorated with carbohydrate structures (or glycans) in a process called glycosylation.
Alex van der Kaaij, Kim van Noort, Pieter Nibbering, Ruud H. P. Wilbers, Arjen Schots   +4 more
doaj   +1 more source

Recombinant expression systems: the obstacle to helminth vaccines? [PDF]

, 2007
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Claerebout, Edwin, De Maere, Veerle, Geldhof, Peter, Vercruysse, Jozef   +3 more
core   +2 more sources

Advances in Double‐Stranded DNA Targeting Technologies

Exploration, EarlyView.
Double‐stranded DNA (dsDNA) plays a crucial role in genetic information storage and disease management, but its inherent stability limits access to internal bases. To overcome this challenge, various high‐specificity molecular targeting technologies have been developed to destabilize the DNA structure.
Zuhao Shen, Yiqun Liu, Yingjie Hao, Yifan Bo, Xiaochuan Dai, Shihui Wang, Tian Xia, Xin Su, Huiyu Liu   +8 more
wiley   +1 more source

Considerations and Tips for Promoting Skin Barrier Maintenance and Quality of Life in Patients With Diabetes Mellitus: An Expert Consensus

JEADV Clinical Practice, EarlyView.
ABSTRACT Skin changes such as xerosis and pruritus are common complications among diabetes patients and may lead to serious adverse events such as diabetic foot syndrome and amputations. Evidence suggests that daily application of optimal skincare, including gentle cleansers and moisturizers, may help improve skin barrier function, preventing ...
Robert S. Kirsner, Anneke Andriessen, Brian Berman, Natasha Mesinkovska, Heather Woolery‐Lloyd, Lawrence Schachner   +5 more
wiley   +1 more source