Results 111 to 120 of about 22,513 (248)
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
FEBS Letters, EarlyView.EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
Emerging experimental and computational methods for studying redox‐regulated structural transitions
FEBS Letters, EarlyView.Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding
FEBS Letters, EarlyView.In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança +2 more
wiley +1 more source
The Development of Pupil Voice in a One Form Entry Primary School in the North East of England: Who Benefits and Who Learns? [PDF]
, 2011 This research study examines the development of pupil voice activities within a one-form entry primary school in northern England over a three-year period through a mainly qualitative approach.
WHITTON, SANDRA,JAYNE
core
Translophagy—A potential link between autophagy impairment and translational errors
FEBS Letters, EarlyView.Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk +11 more
wiley +1 more source
Student voices: Experiences of Solomon Islands students in transition from primary school to boarding secondary school [PDF]
, 2010 This study is about students' experiences when in transition from primary schools they attended daily to boarding secondary schools located far from their homes and villages in the Solomon Islands.
Vasethe, Godfrey
core
FEBS Letters, EarlyView.Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell +2 more
wiley +1 more source
The formation and effects of teacher expectations on students [PDF]
, 2001 Plan BThe purpose of this study was to examine the literature dealing with the formation and the effects of varying teacher expectations on students. The study focused on the characteristics of the self-fulfilling prophecy, the factors that lead teachers
Geisler, Scott
core
SpeakQuest - Using 5w1h to Improve Speaking Skills among Level 2 Pupils
Malaysia Journal of Invention and InnovationSpeakQuest is an innovative intervention designed to improve speaking skills among Malaysian English as a Second Language (ESL) learners, specifically targeting primary school pupils aged 10-12 years. Preliminary observations indicated that these pupils
Aishwarriya Sasi +3 more
doaj +2 more sources
‘Guide and Prejudice’— How Argonautes recognize targets across domains of life
FEBS Letters, EarlyView.Argonaute proteins use short nucleic‐acid guides to locate and regulate specific targets across all domains of life. Despite striking diversity—from human gene silencing to bacterial immune defence—all Argonautes share a conserved three‐stage recognition logic: guide‐directed sampling, progressive target pairing with a conformational checkpoint and ...
Jack P. K. Bravo
wiley +1 more source