Results 91 to 100 of about 52,296 (305)

Correlates of Perceived Computer Helplessness [PDF]

open access: yes, 1982
The purpose of this investigation was to determine the relationship between computer experience and selected demographic variables to knowledge about computers; knowledge of computers, experience with computers and selected demographic variables and ...
Macdonald, Susan M. (Susan Marie)
core  

Inoculation against Learned Helplessness [PDF]

open access: yes, 1980
Different patterns of successes and failures which comprised two partial reinforcement schedules were combined with the presence or absence of training in the attribution of effort to assess their relative effectiveness in preventing learned ...
Norman Stein
core   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

open access: yesMolecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan   +16 more
wiley   +1 more source

Mentors' resources and premature match closure in challenging contexts: testing a model of mediating processes in an online and a school-based mentoring program

open access: yesFrontiers in Psychology
IntroductionThis research aimed to investigate the impact of mentors' resources on the premature termination of mentoring relationships in challenging contexts as well as mediating psychological processes.MethodIn two studies, we analyzed the data of 98 ...
Sonja Bayer   +2 more
doaj   +1 more source

THE GEOPOLITICS OF HELPLESSNESS [PDF]

open access: yesCES Working Papers, 2014
The events in Ukraine are in the thick of actuality, at the crossroads of East and West. From a buffer zone it has become an acute space of exhibition of Russia’s interests, on one side, and of the European Union’s, on the other side. As the EU does not have a unique army or a strong political leadership, the presence - as major actors - of NATO and ...
openaire   +2 more sources

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

open access: yesMolecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen   +9 more
wiley   +1 more source

Specifics of Relationship Between Stress and Helplessness in Adolescence

open access: yesТеоретическая и экспериментальная психология
Background. The article considers the problem of helplessness and its contribution to the experience of everyday and traumatic stress. The relevance of the analysis of psychological aspects of helplessness is due to its currently ambiguous ...
Natalya E. Kharlamenkova
doaj   +1 more source

Learned Helplessness and Associated Factors Among Patients with Lung Cancer [PDF]

open access: yes
Fengmei Huang,1,* Yumei Shi,1,* Li Ding,2 Jingui Huang,1 Zhaoli Zhang2 1Department of Medical Oncology, Chongqing University Cancer Hospital, Chongqing, 400030, People’s Republic of China; 2Nursing Department, Chongqing University Cancer Hospital,
Huang F, Huang J, Zhang Z, Ding L, Shi Y
core  

An integration of quadripartite and helplessness-hopelessness models of depression using the Turkish version of the Learned Helplessness Scale (LHS) [PDF]

open access: yes, 2019
The main focus of this study was to investigate links between the diathesis-stress hypotheses of the quadripartite model and the helplessness-hopelessness theory of depression.
Boysan, Murat
core   +1 more source

Interpreting the effects of DNA polymerase variants at the structural level

open access: yesMolecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi   +7 more
wiley   +1 more source

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