Results 71 to 80 of about 195,584 (302)
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
Modeling of demoralization in breast cancer
Frontiers in PsychiatryObjectiveThis study aimed at identifying correlates of demoralization in breast cancer.Materials and methodsInformation was obtained from outpatients with breast cancer at the Oncology Clinic of a university-affiliated hospital in the United States ...
John M. de Figueiredo +3 more
doaj +1 more source
Cell wall target fragment discovery using a low‐cost, minimal fragment library
FEBS Letters, EarlyView.LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
A literature review on learned helplessness in school environments [PDF]
, 2017 Learned helplessness is a form of learning which develops when the subject perceives a loss of control in inescapable situations. This can lead to the development of cognitive and social deficits.
Cabeza Loriente, Alberto Manuel
core +1 more source
FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
ISPRS International Journal of Geo-InformationThe COVID-19 outbreak followed by the strict citywide lockdown in Shanghai has sparked negative emotion surges on social media platforms in 2022. This research aims to investigate the spatial–temporal heterogeneity of a unique emotion (helplessness) and ...
Yuhao He +4 more
doaj +1 more source
Social and motivational influences on reading [PDF]
, 1983 Pages numbered 1-70Bibliography: p. 47-69Supported in part by the National Institute of Education under contract no.
Asher, Steven R., Wigfield, Allan
core
Responding to Sexual Discrimination: The effects of societal versus self-blame [PDF]
, 1994 While self-blame has been considered to be a useful coping tool for victims, its benefits within the context of group discrimination are equivocal. The present research hypothesized that women encouraged to engage in self-blame for sex discrimination ...
Foster, Mindi D +2 more
core +3 more sources
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Trato y maltrato: una mirada psicoanalítica
Cuestiones de Género: de la Igualdad y la Diferencia, 2008 Veremos las razones por las que tratamientos con maltratadas fracasan. Repasaremos con Freud el devenir mujer: el desamparo radical del ser humano —la Hilflosighkeit freudiana— tiene connotaciones de cataclismo para las mujeres, y con él se confrontan ...
María Cruz Estada
doaj +1 more source