Results 51 to 60 of about 42,522 (262)

Measuring the Spatial-Temporal Heterogeneity of Helplessness Sentiment and Its Built Environment Determinants during the COVID-19 Quarantines: A Case Study in Shanghai

ISPRS International Journal of Geo-Information
The COVID-19 outbreak followed by the strict citywide lockdown in Shanghai has sparked negative emotion surges on social media platforms in 2022. This research aims to investigate the spatial–temporal heterogeneity of a unique emotion (helplessness) and ...
Yuhao He, Qianlong Zhao, Shanqi Sun, Wenjing Li, Waishan Qiu   +4 more
doaj   +1 more source

The ubiquitin system in normal and infected germinal center B cells

FEBS Letters, EarlyView.
The ubiquitin system plays a central role in germinal center (GC) B cells, influencing differentiation to long‐lived memory B cells. Oncogenic gammaherpesviruses gain access to memory B cells by establishing latency in GC B cells. Mapping ubiquitin mechanisms in normal and infected GC B cells will define specific molecular circuits in B cells germane ...
Destiny Davis, Lesly Mejia, Emily K Moser   +2 more
wiley   +1 more source

Smaller is better: nanobodies meet NMR

FEBS Letters, EarlyView.
Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley   +1 more source

Learned helplessness and learned controllability: from neurobiology to cognitive, emotional and behavioral neurosciences

Frontiers in Psychiatry
The sustained and prolonged exposure to environmental stressors may provoke different reactions, depending on the subjective perception of control. Repeated perception of lack of control may lead to learned helplessness, which has been linked to the ...
Gustavo E. Tafet, Tomas Ortiz Alonso
doaj   +1 more source

Trato y maltrato: una mirada psicoanalítica

Cuestiones de Género: de la Igualdad y la Diferencia, 2008
Veremos las razones por las que tratamientos con maltratadas fracasan. Repasaremos con Freud el devenir mujer: el desamparo radical del ser humano —la Hilflosighkeit freudiana— tiene connotaciones de cataclismo para las mujeres, y con él se confrontan ...
María Cruz Estada
doaj   +1 more source

Invisible but not inaccessible—Revealing transient oligomers formed by intrinsically disordered proteins with solution NMR and complementary methods

FEBS Letters, EarlyView.
Transient oligomers formed by intrinsically disordered proteins may be ‘invisible’ to direct detection yet remain accessible to solution NMR through equilibrium‐exchange measurements and pressure‐jump experiments. Complementary methods report on mass, stoichiometry, selected distance distributions, morphology, and internal packing.
Martin D. Gelenter, Ad Bax
wiley   +1 more source

Psychosocial Problems of Thalassemic in A Tertiary Care Centre, Indore

National Journal of Community Medicine, 2016
Introduction: Chronicity of thalassemia is a powerful source of emotional problems. During adolescence and young adulthood various complications may occur and patient under goes a period of psychological readjustment. Material and Methods: This was a
Sameer Inamdar, Anila Gangrade
doaj  

Membrane composition and thermodynamic identity as boundaries of life for synthetic cell research

FEBS Letters, EarlyView.
What makes a cell a cell? The boundary of a living cell is not just a wall. Read as a Markov blanket, the membrane separates internal from external states, generating identity and non‐equilibrium order. Can this identity be rebuilt from scratch in a synthetic cell?
Caterina Presutti, Bert Poolman
wiley   +1 more source

Helplessness in chronic obstructive pulmonary disease patients: Assessment and correlation with sociodemographic factors and spirometry-based severity

Indian Journal of Respiratory Care, 2018
Introduction: Mortality attributable to chronic obstructive pulmonary disease (COPD) in India is estimated to be among the highest in the world. Although identification and management of symptoms and signs of chronic lung diseases have improved, the ...
Akshee Batra, Garvit Chhabra, Pradeep Kumar Gupta   +2 more
doaj   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source