Results 51 to 60 of about 6,736 (217)

Complete analysis of the H5 hemagglutinin and N8 neuraminidase phylogenetic trees reveals that the H5N8 subtype has been produced by multiple reassortment events [PDF]

, 2016
The analysis of the complete H5 hemagglutinin and H8 neuraminidase phylogenetic trees presented in this paper shows that the H5N8 avian influenza has been generated by multiple reassortment events.
A Dalby, A Dalby, A Dalby, A Rambaut, C Adlhoch, D Alexander, D Lee, F Matsen, G Smith, H Ip, H Shimodaira, H Wu, H Yoon, J Brown, J Jeong, J Pasick, J Verhagen, K Ku, K Tamura, M Jhung, M Price, R Squires, X Xu, Y Bao, Y Lee   +24 more
core   +1 more source

Trends of influenza B during the 2010–2016 seasons in 2 regions of north and south Italy: The impact of the vaccine mismatch on influenza immunisation strategy [PDF]

, 2018
Influenza A and B viruses are responsible for respiratory infections, representing globally seasonal threats to human health. The 2 viral types often co-circulate and influenza B plays an important role in the spread of infection.
Alicino C., Ansaldi F., Calamusa G., Canepa P., Colomba G. M. E., Orsi A., Pojero F., Tramuto F., Trucchi C., Vitale F.   +9 more
core   +1 more source

Isolation of novel sequences targeting highly variable viral protein hemagglutinin

MethodsX, 2015
Rapid evolution is a hallmark of the viral kingdom and a major concern for developing universal vaccines. The isolation of substantial numbers of viral sequence variants at highly variable viral protein domains remains a major challenge. We previously developed a combinatorial method for the isolation of novel sequences to cope with rapid viral ...
Zhiwu Xu, Jieyu Wu, Fan Feng, Xiaoxiao Zhang, Xiaoqian Ma, Man Tang, Yan Huang, Ying Zhang, Yongchang Cao, Weiguo Cao, Ran He, Ye Gao, Qiuyun Liu   +12 more
openaire   +3 more sources

The Host Cell Receptors for Measles Virus and Their Interaction with the Viral Hemagglutinin (H) Protein [PDF]

Viruses, 2016
The hemagglutinin (H) protein of measles virus (MeV) interacts with a cellular receptor which constitutes the initial stage of infection. Binding of H to this host cell receptor subsequently triggers the F protein to activate fusion between virus and host plasma membranes.
Liang-Tzung Lin, Christopher D. Richardson   +1 more
openaire   +3 more sources

Reconstruction of the 1918 Influenza Virus: Unexpected Rewards from the Past [PDF]

, 2012
The influenza pandemic of 1918–1919 killed approximately 50 million people. The unusually severe morbidity and mortality associated with the pandemic spurred physicians and scientists to isolate the etiologic agent, but the virus was not isolated in 1918.
Ballinger, Centers for Disease Control and Prevention, Dunham, Easterbrook, Ekiert, Fleishman, Francis, Garten, Herfst, Imai, Jagger, Jain, Johnson, Kash, Kobasa, Kobasa, Kuiken, Mehle, Mehle, Memoli, Morens, Morens, Morens, Nabel, Nakamura, Obenauer, Pappas, Pearce, Qi, Qi, Rabadan, Rambaut, Reid, Russell, Sheng, Smith, Stevens, Stevens, Stevens, Tan, Taubenberger, Taubenberger, Taubenberger, Taubenberger, Taubenberger, Tumpey, Tumpey, Van Hoeven, Watanabe, Xu, Yu   +50 more
core   +3 more sources

Glycans as receptors for influenza pathogenesis [PDF]

, 2010
Influenza A viruses, members of the Orthomyxoviridae family, are responsible for annual seasonal influenza epidemics and occasional global pandemics.
A Chandrasekaran, A Gambaryan, A Gottschalk, A Srinivasan, A Varki, Aarthi Chandrasekaran, Aravind Srinivasan, AS Gambaryan, AS Gambaryan, AS Gambaryan, AS Gambaryan, C Basler, C Traving, CA Bewley, CW Lee, DA Steinhauer, DC Nguyen, DC Wiley, E Klenk, F Zilliken, G Neumann, GK Hirst, GN Rogers, HL Yen, IA Wilson, J Stevens, J Stevens, JC Paulson, JJ Skehel, JK Taubenberger, JM Nicholls, K Kumari, K Shinya, Karthik Viswanathan, LA Perrone, LG Baum, M Bernfield, M Matrosovich, M Matrosovich, M Matrosovich, MB Eisen, MD Jong de, MI Nelson, NM Varki, O Blixt, O Blixt, P Bohm, P Palese, PH Seeberger, R Raman, R Raman, R Sasisekharan, Rahul Raman, Ram Sasisekharan, RJ Connor, RJ Russell, RJ Russell, RL Chen, S Hanson, S Yamada, SJ Gamblin, T Ito, T Kuiken, TH Tran, TM Tumpey, TM Tumpey, TM Tumpey, TM Tumpey, TR Maines, TR Maines, V. Sasisekharan, X Song, Y Ha, Y Ha, Y Suzuki, ZY Yang   +75 more
core   +1 more source

Uptake of reovirus serotype 1 by the lungs from the bloodstream is mediated by the viral hemagglutinin [PDF]

Journal of Virology, 1988
We used the mammalian reoviruses to determine the molecular basis of the clearance of a virus from the bloodstream by specific organs. Reovirus serotypes 1 (T1) and 3 (T3) were radiolabeled with [35S]methionine or 125I, and the viruses were injected intravenously into weanling rats. The distribution of radioactivity within the animals was determined at
E M, Verdin, S P, Lynn, B N, Fields, E, Maratos-Flier   +3 more
openaire   +2 more sources

A Homogenous Fluorescence Quenching Based Assay for Specific and Sensitive Detection of Influenza Virus A Hemagglutinin Antigen

Sensors, 2015
Influenza pandemics cause millions of deaths worldwide. Effective surveillance is required to prevent their spread and facilitate the development of appropriate vaccines.
Longyan Chen, Suresh Neethirajan
doaj   +1 more source

Unexpected interfarm transmission dynamics during a highly pathogenic avian influenza epidemic [PDF]

, 2016
Next-generation sequencing technology is now being increasingly applied to study the within- and between-host population dynamics of viruses. However, information on avian influenza virus evolution and transmission during a naturally occurring epidemic ...
Bonfanti, Lebana, Cattoli, Giovanni, Fusaro, Alice, Hughes, Joseph, Marangon, Stefano, Massi, Paola, Milani, Adelaide, Monne, Isabella, Murcia, Pablo R., Salviato, Annalisa, Schultz-Cherry, S., Tassoni, Luca, Zamperin, Gianpiero   +12 more
core   +1 more source

A Live-Attenuated Prime, Inactivated Boost Vaccination Strategy with Chimeric Hemagglutinin-Based Universal Influenza Virus Vaccines Provides Protection in Ferrets: A Confirmatory Study

Vaccines, 2018
Influenza viruses cause severe diseases and mortality in humans on an annual basis. The current influenza virus vaccines can confer protection when they are well-matched with the circulating strains.
Raffael Nachbagauer, Florian Krammer, Randy A. Albrecht   +2 more
doaj   +1 more source