Results 31 to 40 of about 6,736 (217)

Overview of Serological Techniques for Influenza Vaccine Evaluation: Past, Present and Future [PDF]

, 2014
Serological techniques commonly used to quantify influenza-specific antibodies include the Haemagglutination Inhibition (HI), Single Radial Haemolysis (SRH) and Virus Neutralization (VN) assays.
Callow, Calza, Chan, Cosma, De Jong, Farrohi, Ferrara, Fox, Frank, Fulton, Gross, Halloran, Harmon, Hierholzer, Johansson, Johansson, Kendal, Kilbourne, Montomoli, Okuno, O’Neill, Powers, Probert, Rowe, Schild, Schulman, Schulman, Scott, Sylte, Van Assen, Yewdell   +30 more
core   +3 more sources

A single amino acid substitution in the novel H7N9 influenza A virus NS1 protein increases CPSF30 binding and virulence [PDF]

, 2014
Although an effective interferon antagonist in human and avian cells, the novel H7N9 influenza virus NS1 protein is defective at inhibiting CPSF30. An I106M substitution in H7N9 NS1 can restore CPSF30 binding together with the ability to block host gene ...
Ayllon, Juan, Domingues, Patricia, Garcia-Sastre, Adolfo, Hale, Benjamin G., Miorin, Lisa, Rajsbaum, Ricardo, Schmolke, Mirco   +6 more
core   +11 more sources

One-way trip: Influenza virus' adaptation to gallinaceous poultry may limit its pandemic potential [PDF]

, 2014
We hypothesise that some influenza virus adaptations to poultry may explain why the barrier for human-to-human transmission is not easily overcome once the virus has crossed from wild birds to chickens.
Alexander, Baigent, Banks, Banks, Belser, Blumenkrantz, Bosch, Brass, Bullough, Butt, Castrucci, Cauldwell, Chan, Chen, Chen, Cheng, Chutinimitkul, Cohen, Connor, Costa, Cotter, Cowling, Cox, De Jong, Dorigatti, DuBois, Elderfield, England, Everitt, Gabbard, Galloway, Gambaryan, Gambaryan, Gao, Garten, Handel, Harvey, Hatta, Hay, Herfst, Hoffmann, Imai, Jia, Karron, Keleta, Killingley, Koerner, Koopmans, Krenn, Kuchipudi, Li, Li, Lin, Lin, Linster, Luke, Maines, Matrosovich, Matrosovich, Matrosovich, Matrosovich, Matsuoka, Munier, Neumann, O'Donnell, Pappas, Peiris, Perdue, Reed, Roberts, Robinson, Roche, Rogers, Rott, Russell, Russell, Schrauwen, Shelton, Shi, Skehel, Smeenk, Sorrell, Sorrell, Steinhauer, Stevens, Suguitan, Sun, Tellier, Tharakaraman, Thoennes, Tumpey, Vines, Wan, Wang, Washington, Webster, Wei, Xiong, Yen, Zhang, Zhou, Zhou   +101 more
core   +2 more sources

Stimulation of Heterophil Hemagglutinins in Chickens by a Viral Vaccine and Chicken Thyroid Extract [PDF]

Acta Veterinaria Scandinavica, 1973
The formation of heteroag-glutinins against human group O, horse and sheep erythrocytes was studied in groups of chickens injected with various materials. Production of antibodies cross-reacting with some or all of the test cell types was induced both with chicken thyroid extract, with or without adjuvant, and with inactivated infectious bronchitis ...
D, Sharma, J, Tuomi
openaire   +2 more sources

Glycan receptor specificity as a useful tool for characterization and surveillance of influenza A virus [PDF]

, 2014
Influenza A viruses are rapidly evolving pathogens with the potential for novel strains to emerge and result in pandemic outbreaks in humans. Some avian-adapted subtypes have acquired the ability to bind to human glycan receptors and cause severe ...
Jayaraman, Akila, Raman, Rahul, Sasisekharan, Ram, Sasisekharan, Viswanathan, Shriver, Zachary H., Tharakaraman, Kannan   +5 more
core   +1 more source

Recognition of viral hemagglutinins by NKp44 but not by NKp30

European Journal of Immunology, 2001
Natural killer (NK) cells destroy virus-infected and tumor cells without prior antigen stimulation. The NK cell cytotoxicity is regulated in large part by the expression of NK cell receptors that are able to bind major histocompatibility complex (MHC) class I glycoproteins.
Arnon, T, Lev, M, Katz, G, Chernobrov, Y, Porgador, A, Mandelboim, O   +5 more
openaire   +3 more sources

Viral factors in influenza pandemic risk assessment [PDF]

, 2016
The threat of an influenza A virus pandemic stems from continual virus spillovers from reservoir species, a tiny fraction of which spark sustained transmission in humans.
Barclay, Wendy, Beauchemin, Catherine A.A., Bedford, Trevor, Belser, Jessica A., Cobey, Sarah, Friedrich, Thomas C., Handel, Andreas, Herfst, Sander, Kasson, Peter M., Lipsitch, Marc, Lloyd-Smith, James O., Maurer-Stroh, Sebastian, Murcia, Pablo R., Raman, Rahul, Riley, Steven, Roche, Benjamin, Russell, Charles J., Russell, Colin A., Wilke, Claus O.   +18 more
core   +4 more sources

Cross-protection between antigenically distinct H1N1 swine influenza viruses from Europe and North America [PDF]

, 2011
Background An avian-like H1N1 swine influenza virus (SIV) is enzootic in swine populations of Western Europe. The virus is antigenically distinct from H1N1 SIVs in North America that have a classical swine virus-lineage H1 hemagglutinin, as does the ...
Brookes, Brown, Brown, Brown, Brownlee, Dürrwald, Garten, Grebe, Guan, Hinshaw, Hofshagen, Itoh, Kingsford, Kyriakis, Lange, Maurer-Stroh, Miller, Olsen, Olsen, Pensaert, Reed, Sandbulte, Scholtissek, Smith, Takemae, Van Reeth, Van Reeth, Van Reeth, Van Reeth, Van Reeth, Weingartl   +30 more
core   +1 more source

The use of equine influenza pseudotypes for serological screening [PDF]

, 2012
Standard assays used for influenza serology present certain practical issues, such as inter-laboratory variability, complex protocols and the necessity for handling certain virus strains in high biological containment facilities.
Böttcher-Friebertshäuser, Eva, Daly, Janet, Ferrara, Francesca, Molesti, Eleonora, Scott, Simon, Temperton, Nigel   +5 more
core   +4 more sources

Potent Anti-Influenza Activity of Cyanovirin-N and Interactions with Viral Hemagglutinin [PDF]

Antimicrobial Agents and Chemotherapy, 2003
ABSTRACT The novel antiviral protein cyanovirin-N (CV-N) was initially discovered based on its potent activity against the human immunodeficiency virus (HIV). Subsequent studies identified the HIV envelope glycoproteins gp120 and gp41 as molecular targets of CV-N.
O'Keefe, B. R., Smee, Donald F., Turpin, J. A., Saucedo, C. J., Gustafson, K. R., Mori, T., Blakeslee, D., Buckheit, R., Boyd, M. R.   +8 more
openaire   +3 more sources