Results 11 to 20 of about 6,736 (217)
Antibody-Based Strategies to Prevent and Treat Influenza [PDF]
Frontiers in Immunology, 2015 Passive immunization using antibodies has been suggested to offer several benefits in comparison to other antiviral treatment options. The potential for seasonal protection arising from a single injection of antibodies is appealing and has been pursued ...
Ram eSasisekharan, Zachary eShriver
doaj +3 more sources
Distribution of O-Acetylated Sialic Acids among Target Host Tissues for Influenza Virus [PDF]
mSphere, 2017 Sialic acids (Sias) are important glycans displayed on the cells and tissues of many different animals and are frequent targets for binding and modification by pathogens, including influenza viruses.
Brian R. Wasik +9 more
doaj +5 more sources
Immunogenicity of chimeric hemagglutinins delivered by an orf virus vector platform against swine influenza virus [PDF]
Frontiers in ImmunologyOrf virus (ORFV) is a large DNA virus that can harbor and efficiently deliver viral antigens in swine. Here we used ORFV as a vector platform to deliver chimeric hemagglutinins (HA) of Influenza A virus of swine (IAV-S). Vaccine development against IAV-S
Gabriela Mansano do Nascimento +4 more
doaj +2 more sources
Insight into highly conserved H1 subtype-specific epitopes in influenza virus hemagglutinin [PDF]
, 2014 Influenza viruses continuously undergo antigenic changes with gradual accumulation of mutations in hemagglutinin (HA) that is a major determinant in subtype specificity.
Cho, Ki Joon +7 more
core +21 more sources
Evolutionarily conserved amino acids in MHC-II mediate bat influenza A virus entry into human cells.
PLoS Biology, 2023 The viral hemagglutinins of conventional influenza A viruses (IAVs) bind to sialylated glycans on host cell surfaces for attachment and subsequent infection. In contrast, hemagglutinins of bat-derived IAVs target major histocompatibility complex class II
Okikiola M Olajide +10 more
doaj +1 more source
High-complexity extracellular barcoding using a viral hemagglutinin [PDF]
Proceedings of the National Academy of Sciences, 2020 While single-cell sequencing technologies have revealed tissue heterogeneity, resolving mixed cellular libraries into cellular clones is essential for many pooled screens and clonal lineage tracing. Fluorescent proteins are limited in number, while DNA barcodes can only be read after cell lysis.
Gavriel Mullokandov +7 more
openaire +3 more sources
Molecular Therapy: Nucleic Acids, 2022 Increasing preclinical and clinical results have demonstrated that mRNA vaccines efficiently prevent infectious diseases and are safe in animal models and humans.
Wandi Zhu +7 more
doaj +1 more source
A simple procedure for purification of viral hemagglutinin [PDF]
Virology, 1962 Peer Reviewed ; http://deepblue.lib.umich.edu/bitstream/2027.42/32311/1/0000379 ...
Mizutani, H. +3 more
openaire +3 more sources
Biomolecules, 2020 An aptamer is a synthetic oligonucleotide with a unique spatial structure that provides specific binding to a target. To date, several aptamers to hemagglutinin of the influenza A virus have been described, which vary in affinity and strain specificity ...
Anastasia A. Novoseltseva +9 more
doaj +1 more source
The specificity of targeted vaccines for APC surface molecules influences the immune response phenotype. [PDF]
PLoS ONE, 2013 Different diseases require different immune responses for efficient protection. Thus, prophylactic vaccines should prime the immune system for the particular type of response needed for protection against a given infectious agent.
Gunnveig Grødeland +4 more
doaj +1 more source