Results 101 to 110 of about 6,677 (208)
MedComm, Volume 7, Issue 8, August 2026.Mycobacterium tuberculosis–host interactions and infection outcomes. Following initial infection, alveolar macrophages phagocytose the pathogen, prompting the recruitment of innate immune cells including neutrophils, NK cells, and interstitial macrophages.
Xiaojuan Zhang +3 more
wiley +1 more source
Cancer Science, Volume 117, Issue 8, Page 2166-2180, August 2026.Lysine acetyltransferase 2A (KAT2A) is a transcriptional coactivator and a member of the Histone Acetyltransferase (HAT) family. While altered KAT2A activity has been implicated in various cancers, its role in bladder cancer (BLCA) remains poorly understood.
Wenjie Yang +8 more
wiley +1 more source
Immunological Reviews, Volume 341, Issue 1, August 2026.ABSTRACT Preexisting immunity to influenza confers rapid protection against antigenically matched viruses but can also constrain responses to drifted variants. This review asks when and why prior infection or vaccination is protective versus detrimental, and which biological mechanisms—epitope masking by circulating antibody, inhibitory FcγRIIb ...
Annette Fox +2 more
wiley +1 more source
Counteracting Influenza Virus Evolution Through the Full Spectrum of Broadly Protective Antibodies
Immunological Reviews, Volume 341, Issue 1, August 2026.ABSTRACT Despite the presence of licensed vaccines and therapeutics, influenza viruses remain a major public health concern, as they cause seasonal respiratory infections and pose a pandemic threat through the emergence of zoonotic strains. Although neutralizing antibodies elicited by seasonal vaccination constitute a primary defense against infection,
Yu Adachi, Yoshimasa Takahashi
wiley +1 more source
GC B Cells, Tfh Cells, and Influenza bnAbs: Insights for Improving Universal Vaccine Design
Immunological Reviews, Volume 341, Issue 1, August 2026.ABSTRACT Antibodies are crucial for providing protection against influenza virus infection; however, protective humoral immunity is limited by antigenic drift and shift. Hence, the discovery of broadly neutralizing antibodies (bnAbs) targeting conserved epitopes on hemagglutinin protein evokes the hope of developing a universal influenza vaccine ...
Takeshi Inoue +2 more
wiley +1 more source
Journal of Cellular and Molecular Medicine, Volume 30, Issue 15, August 2026.ABSTRACT Proteolysis‐targeting chimeras (PROTACs) are heterobifunctional molecules that hijack the ubiquitin‐proteasome system to drive catalytic, sub‐stoichiometric degradation of disease‐associated proteins, offering a mechanistic advantage over occupancy‐driven inhibitors and access to ‘undruggable’ targets.
Sruti Bagchi Ghosh +9 more
wiley +1 more source
To Move or Not to Move: When and How Bacteria Suppress Flagellar Motility
Molecular Microbiology, Volume 126, Issue 2, Page 173-189, August 2026.Motility cessation in bacteria is a key regulatory strategy that provides multiple survival advantages including enhanced community cooperation, niche adaptation and evasion of host immune responses. This process is controlled by associated mechanisms such as post‐translational modifications and second messenger signalling that stabilise non‐motile ...
Fatemeh Mohaghegh +2 more
wiley +1 more source
Hemagglutinin-displaying influenza nanovaccines: progress and promise. [PDF]
Nanomedicine (Lond)Kim D +5 more
europepmc +1 more source
Phylogenetic Groups, Virulence Factors, and Antimicrobial Susceptibility of <i>Escherichia coli</i> Associated with Urinary Tract Infections from a Metropolitan Area of Buenos Aires, Argentina. [PDF]
Antibiotics (Basel)Molina NB +3 more
europepmc +1 more source