Results 41 to 50 of about 604 (128)

Expression of CD5 on hematogones in a 7-year-old girl with Shwachman-Diamond syndrome.

, 2001
We report increased numbers of hematogones in a 7-year-old girl with pancytopenia due to Shwachman-Diamond syndrome. Her hematogones expressed the T-cell marker CD5 as well as CD19, CD10, and CD20, and terminal deoxynucleotidyl transferase and HLA-DR ...
Jelic, T M, Chang, H H, Kurczynski, E M, Tolaymat, Naser, MD, Raj, A B, Jin, B   +5 more
core   +1 more source

Hematogones: a new prognostic factor for acute myeloblastic leukemia

, 2011
Acute myeloid leukemia (AML) patient outcomes remain heterogeneous, and new prognostic tools are needed to assess the risk of relapse. Hematogones (HGs) are normal B-lymphocyte precursors, which increase in number in hematologic diseases.
Jean Pierre Vilque, Oumedaly Reman, Margaret Macro, Stephane Cheze, Florence Truquet, Véronique Salaün, Sylvain P. Chantepie, Jean-Jacques Parienti   +7 more
core   +1 more source

COMIP‐002: 27‐color flow cytometry for measurable residual disease detection in B‐cell lymphoblastic leukemia

Cytometry Part B: Clinical Cytometry, Volume 110, Issue 5, Page 321-325, September 2026.
Ryan C. Shean, Patricia Davis, Jeffery Jacobsen, David P. Ng   +3 more
wiley   +1 more source

Focus on the Holdrinet index: Toward blast quantification by flow cytometry

Cytometry Part B: Clinical Cytometry, Volume 108, Issue 2, Page 137-145, March 2025.
Abstract Blast quantification in the bone marrow (BM) is crucial for evaluating myeloid neoplasms, with cytomorphology being the only recognized analysis. The CD34 myeloid cell (CD34M) count by flow cytometry is promising but impaired by BM hemodilution.
Edouard Bonneville, Marie‐Christine Jacob, Simon Chevalier, Martine Pernollet, Chantal Dumestre‐Perard, Giovanna Clavarino   +5 more
wiley   +1 more source

Diagnostic features in paediatric MDS‐EB with UBTF‐internal tandem duplication: defining a unique subgroup

Histopathology, Volume 86, Issue 4, Page 603-610, March 2025.
Distinctive histopathological features of paediatric MDS with UBTF‐TD include hyperplastic myelopoiesis with severe atypia, frequent micromegakaryocytes, and immature erythropoiesis with circulating normoblasts. These findings may aid in the early diagnosis and guide targeted molecular testing and treatment strategies, which are critical to improving ...
Stephan Schwarz‐Furlan, Carole Gengler, Ayami Yoshimi‐Noellke, Guido Piontek, Yuki Schneider‐Kimoto, Markus Schmugge, Christian Thiede, Charlotte M. Niemeyer, Miriam Erlacher, Martina Rudelius   +9 more
wiley   +1 more source

Clinical and Morphological Bone Marrow Characteristics of Pearson Syndrome: About Three Consecutive Cases and Review of the Literature

Case Reports in Pediatrics, Volume 2025, Issue 1, 2025.
Pearson syndrome (PS) is a rare and fatal multisystem disorder caused by a mitochondrial DNA (mtDNA) deletion. Most patients develop refractory anemia in early infancy, rapidly followed by multiple complications such as failure to thrive, muscle hypotonia, pancreatic insufficiency, and renal tubulopathy. Although the definitive diagnosis is established
Gaetan-Nagim Degroot, Aurélie Empain, Laurence Dedeken, Anne Demulder, Laurence Rozen, Anselm Chi-wai Lee   +5 more
wiley   +1 more source

Identification of early B cell precursors (stage 1 and 2 hematogones) in the peripheral blood

, 2018
Differentiating malignant B-lymphoblasts from early benign B cell precursors (hematogones) is a vital component of the diagnosis of B-lymphoblastic leukaemia.
Olga K Weinberg, Jason H Kurzer
core   +1 more source

Effects of Storage Temperature and Duration on Flow Cytometry Analysis of Bone Marrow Aspirate Samples

, 2022
Introduction/Objective Multiparameter flow cytometry immunophenotyping is a powerful and indispensable tool in the diagnosis of hematologic malignancies, but its accuracy and precision are vulnerable to pre-analytical interferences. Acid-citrate-dextrose
Cevallos, S, Chen, C, Zhou, Y
core   +1 more source

CD38, CD39, and BCL2 differentiate disseminated forms of high‐grade B‐cell lymphomas in biological fluids from Burkitt lymphoma and diffuse large B‐cell lymphoma

Cytometry Part B: Clinical Cytometry, Volume 106, Issue 6, Page 448-464, November 2024.
Abstract High‐grade B‐cell lymphomas (HGBCL) represent a heterogeneous group of very rare mature B‐cell lymphomas. The 4th revised edition of the WHO Classification of Tumors of Hematopoietic and Lymphoid Tissues (WHO‐HAEM) previously defined two categories of HGBCL: the so‐called double‐hit (DHL) and triple‐hit (THL) lymphomas, which were related to ...
Pauline Marianini, Vanessa Lacheretz‐Szablewski, Marion Almeras, Jérôme Moreaux, Caroline Bret   +4 more
wiley   +1 more source

Utility of leukocyte‐associated immunoglobulin‐like receptor‐1 (CD305) in flow cytometric detection of minimal bone marrow involvement by B‐cell non‐Hodgkin lymphoma

Cytometry Part B: Clinical Cytometry, Volume 106, Issue 5, Page 359-369, September 2024.
Abstract Multicolor flow cytometry (MFC) is crucial in detecting occult or minimal bone marrow (BM) involvement by non‐Hodgkin lymphomas (NHL), which may not be detected using trephine biopsy or imaging studies. Detection of low‐level BM involvement can be challenging without definite immunophenotypic aberrancies. We studied the utility of CD305 in MFC
Anu Singh, Jagruti Patil, Sitaram G. Ghogale, Nilesh Deshpande, Karishma Girase, Navami Shetye, Sweta Rajpal, Gaurav Chatterjee, Nikhil Patkar, Disha Jain, Sridhar Epari, Tanuja Shet, Sumeet Gujral, Papagudi G. Subramanian, Prashant R. Tembhare   +14 more
wiley   +1 more source