Results 111 to 120 of about 218,075 (284)

The genetic and symptomatic link of polycythemia vera. narrative review

Revista Mexicana de Investigación Médica
Myeloproliferative neoplasms (MPNs), such as essential thrombocythemia (ET), primary myelofibrosis (PMF), and polycythemia vera (PV), are clonal hematologic disorders.
Asheley Jezabel Flores Hernández, Alondra Elizabeth Pérez Tlapa, Felix Santos González, Yessica Ibelith Cosme Herrera   +3 more
doaj   +1 more source

Association of Elevated Platelets and C‐Reactive Protein With Severe Disease and Poor Survival in Systemic Sclerosis

Arthritis Care &Research, EarlyView.
Objective Elevated C‐reactive protein (CRP) levels in systemic sclerosis (SSc) have been linked with severe disease and worse survival, but the role of platelet levels remains unclear. This study examined whether elevated platelet levels, CRP levels, or both are associated with disease severity, progression, and survival in SSc.
Brian S. Lee, Shufeng Li, Srijana Davuluri, Jennifer Lee, Lorinda Chung   +4 more
wiley   +1 more source

Impact of Six‐Month Monitoring Compared to Three‐Month Monitoring of Laboratories During Methotrexate Therapy

Arthritis Care &Research, EarlyView.
Objective To evaluate whether extending the American College of Rheumatology–recommended monitoring interval for complete blood count and liver function tests in patients receiving methotrexate (MTX) affects timely detection of medication‐related toxicity.
Spencer Simko, Ray Zhang, Sohini Mukherjee, Puneet Bajaj, Bonnie L. Bermas   +4 more
wiley   +1 more source

Dermatological manifestations of hematologic neoplasms. Part II: nonspecific skin lesions/paraneoplastic diseases. [PDF]

An Bras Dermatol, 2023
de Souza PK, Amorim RO, Sousa LS, Batista MD.   +3 more
europepmc   +1 more source

Selenium‐Integrated Cyanine Dye With Enhanced Photophysical Properties for Optoacoustic‐Guided Cancer Imaging and Therapy

Advanced Functional Materials, EarlyView.
This study introduces selenium‐integrated cyanine dye (Se‐Cyn), with superior photostability, absorption, and photothermal efficiency, outperforming ICG in NIR window. Its nanoparticle form remains stable in water, accumulates in tumors, and enables strong optoacoustic imaging and effective phototherapy outcomes.
Divyesh Shelar, Snehal Salunkhe, Tony Fröhlich, Uwe Klemm, Pia Anzenhofer, Birgit Rathkolb, Martin Hrabě de Angelis, Oliver Plettenburg, Michael Sattler, Sudesh T. Manjare, Vipul Gujrati, Vasilis Ntziachristos   +11 more
wiley   +1 more source

Case Report: Myeloid neoplasms with the t(3;12)(q26.2;p13.1)/MECOM-ETV6 translocation: report of two new cases and review of the literature

Frontiers in Oncology
The MECOM (MDS1 and EVI1 complex locus) gene, located at 3q26.2, encodes an oncogenic transcription factor implicated in multiple signaling pathways.
Soumya Mikkilineni, Juan Pablo Pineda-Reyes, Lindsay Wilde, Andres Ferber, Zi-Xuan Wang, Stephen Peiper, Guldeep Uppal, Jerald Gong, Jinglan Liu   +8 more
doaj   +1 more source

Bone Organoids Across the Development‐to‐Remodeling Continuum: From Tissue Formation to Functional Competence and Translation

Advanced Healthcare Materials, EarlyView.
Mineralization alone does not establish a mature bone organoid. This Review integrates biological foundations, materials design, adaptive remodeling, and translational validation through the development‐to‐remodeling continuum (DRC). By separating biological functions from the evidence supporting them, the framework exposes critical gaps in current ...
Xijie Tang, Haijia Xu, Xiangzhong Liu, Yi Yang, Zhanghua Li   +4 more
wiley   +1 more source

A Brief Review on the Role of the Transcription Factor PBX1 in Hematologic Malignancies

Pre-B-cell leukemia factor 1 (PBX1) is a transcription factor that plays a significant role in various physiological, developmental, and oncogenic processes in humans.
Maria Papaioannou, Chatzileontiadou, Sofia, Kassiani Boulogeorgou, Frouzaki, Christina, Papaioannou, Maria, Boulogeorgou, Kassiani, Sofia Chatzileontiadou, Hatjiharissi, Evdoxia, Koletsa, Triantafyllia, Triantafyllia Koletsa, Evdoxia Hatjiharissi, Christina Frouzaki   +11 more
core   +1 more source

NQO1 C609T polymorphism in distinct entities of pediatric hematologic neoplasms

Haematologica, 2004
BACKGROUND AND OBJECTIVES: NAD(P)H:quinone oxidoreductase 1 (NQO1) is an enzyme that protects cells against mutagenicity from free radicals and toxic oxygen metabolites. The gene coding for NQO1 is subject to a genetic polymorphism at nucleotide position
T Kracht, M Schrappe, S Strehl, A Reiter, HA Elsner, J Trka, G Cario, S Viehmann, J Harbott, A Borkhardt, M Metzler, T Langer, R Repp, R Marschalek, K Welte, OA Haas, M Stanulla   +16 more
doaj  

Colorectal Carcinoma—An Anomalous Trigger of Adult Hemophagocytic Lymphohistiocytosis

Journal of Investigative Medicine High Impact Case Reports
Hemophagocytic lymphohistiocytosis (HLH) is a rare but often fatal condition characterized by a hyperinflammatory immune response leading to multiorgan failure. It is predominantly observed in the pediatric population and can be classified as familial or
Ameish Govindarajan MD, Frederick Venter MD, Akriti Chaudhry MD, Harsimranjit Kaur MD, Everardo Cobos MD, Greti Petersen MD   +5 more
doaj   +1 more source