Molecular Oncology, EarlyView.Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz +15 more
wiley +1 more source
Clinical and histopathological evaluation of 5-fluorouracil-induced oral mucositis in a rat model
Open Veterinary JournalBackground: Chemotherapeutics like 5-fluorouracil (5-FU) may induce a variety of adverse effects, including oral mucositis (OM), which may necessitate treatment discontinuation in patients with cancer.
Ambar Kusuma Astuti +5 more
doaj +1 more source
Failure rate prediction of equipment: can Weibull distribution be applied to automated hematology analyzers? [PDF]
, 2018 Alekh Verma +9 more
openalex +1 more source
Effect of chemotherapy on passenger mutations in metastatic colorectal cancer
Molecular Oncology, EarlyView.Changes in passenger mutation load and predicted immunotherapy response after chemotherapy treatment. Tumor cells rich with passenger mutations have increased sensitivity to chemotherapy. Correlation of passenger mutations with neoantigen load suggests highly mutated clones promote a more effective response to immunotherapy, and therefore, first‐line ...
Marium T. Siddiqui +6 more
wiley +1 more source
Outcomes and Prognostic Factors in Patients with Primary Mediastinal B Cell Lymphoma: An Experience from Hematology Cancer Consortium [PDF]
, 2023 Akhil Rajendra +17 more
openalex +1 more source
Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib
Molecular Oncology, EarlyView.WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute +17 more
wiley +1 more source
Effect of cassava mill effluents on the osmotic and hematology of clarias gariepinus juveniles
, 2013 M. O. Olufayo
openalex +1 more source
Molecular Oncology, EarlyView.Monitoring circulating tumor DNA (ctDNA) in patients with operable breast cancer can reveal disease relapse earlier than radiology in a subset of patients. The failure to detect ctDNA in some patients with recurrent disease suggests that ctDNA could serve as a supplement to other monitoring approaches.
Kristin Løge Aanestad +35 more
wiley +1 more source
Reducing inappropriate antibiotic use in febrile neutropenia in hematology patients through the implementation of an antibiotic de-escalation protocol [PDF]
Jinghao Nicholas Ngiam +8 more
openalex +1 more source
Hematology: Updates, Evidence-Based Care, and Implications for Future Practice [PDF]
, 2019 Thomas A. VanDruff
openalex +1 more source