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On the existence and exponential attractivity of a unique positive almost periodic solution to an impulsive hematopoiesis model with delays [PDF]
Acta Math Vietnam 41 (2016) 337-354, 2015 In this paper, a generalized model of hematopoiesis with delays and impulses is considered. By employing the contraction mapping principle and a novel type of impulsive delay inequality, we prove the existence of a unique positive almost periodic solution of the model.
Anh, Trinh Tuan +2 more
arxiv +3 more sources
Modelling hematopoiesis mediated by growth factors with applications to periodic hematological diseases [PDF]
Bulletin of Mathematical Biology 68, 8 (2006) 2321-2351, 2009 Hematopoiesis is a complex biological process that leads to the production and regulation of blood cells. It is based upon differentiation of stem cells under the action of growth factors. A mathematical approach of this process is proposed to carry out explanation on some blood diseases, characterized by oscillations in circulating blood cells.
Adimy, Mostafa +2 more
arxiv +8 more sources
Bayesian inference and model choice in a hidden stochastic two-compartment model of hematopoietic stem cell fate decisions [PDF]
Annals of Applied Statistics 2009, Vol. 3, No. 4, 1695-1709, 2010 Despite rapid advances in experimental cell biology, the in vivo behavior of hematopoietic stem cells (HSC) cannot be directly observed and measured. Previously we modeled feline hematopoiesis using a two-compartment hidden Markov process that had birth and emigration events in the first compartment.
Abkowitz, Janis +2 more
arxiv +3 more sources
Journal of Allergy and Clinical Immunology, 1994 Cellular turnover of the hematopoietic system is supported by a small population of cells termed hematopoietic stem cells. Stem cells are capable of self-renewal and differentiation into individual lymphomyeloid lineages. Available evidence indicates that the decision of a stem cell to self-renew or differentiate and the decision of a multipotential ...
Makio Ogawa
openalex +3 more sources
A case of intrathoracic extramedullary hematopoiesis-associated pleural effusion in a beta-thalassemia intermedia patient and a short literature review [PDF]
SAGE Open Medical Case ReportsExtramedullary hematopoiesis is a phenomenon that occurs in conditions of ineffective bone marrow function. In the context of thalassemias, extramedullary hematopoiesis is more frequently observed in beta-thalassemia intermedia patients, with thoracic ...
Georgios Petros Barakos +10 more
doaj +2 more sources
Efficient Transition Probability Computation for Continuous-Time Branching Processes via Compressed Sensing [PDF]
arXiv, 2015 Branching processes are a class of continuous-time Markov chains (CTMCs) with ubiquitous applications. A general difficulty in statistical inference under partially observed CTMC models arises in computing transition probabilities when the discrete state space is large or uncountable.
Minin, Vladimir N., Xu, Jason
arxiv +4 more sources
CD14+ monocytes repress gamma globin expression at early stages of erythropoiesis
Scientific Reports, 2021 In β-hemoglobinopathies, reactivation of gamma- at the expense of beta-globin is a prominent therapeutic option. Expression of the globin genes is not strictly intrinsically regulated during erythropoiesis, supported by the observation that fetal ...
Steven Heshusius +3 more
doaj +1 more source
Cold Spring Harbor Perspectives in Biology, 2012 Enormous numbers of adult blood cells are constantly regenerated throughout life from hematopoietic stem cells through a series of progenitor stages. Accessibility, robust functional assays, well-established prospective isolation, and successful clinical application made hematopoiesis the classical mammalian stem cell system. Most of the basic concepts
Rieger, M., Schroeder, T.
openaire +3 more sources
Trends in Immunology, 2021 Hematopoiesis is a dynamic process in which stem and progenitor cells give rise to the ...
Jason Cosgrove +3 more
openaire +5 more sources