Results 1 to 10 of about 134,478 (313)
On the existence and exponential attractivity of a unique positive almost periodic solution to an impulsive hematopoiesis model with delays [PDF]
Acta Math Vietnam 41 (2016) 337-354, 2015 In this paper, a generalized model of hematopoiesis with delays and impulses is considered. By employing the contraction mapping principle and a novel type of impulsive delay inequality, we prove the existence of a unique positive almost periodic solution of the model.
Anh, Trinh Tuan +2 more
arxiv +3 more sources
Modelling hematopoiesis mediated by growth factors with applications to periodic hematological diseases [PDF]
Bulletin of Mathematical Biology 68, 8 (2006) 2321-2351, 2009 Hematopoiesis is a complex biological process that leads to the production and regulation of blood cells. It is based upon differentiation of stem cells under the action of growth factors. A mathematical approach of this process is proposed to carry out explanation on some blood diseases, characterized by oscillations in circulating blood cells.
Adimy, Mostafa +2 more
arxiv +8 more sources
Bayesian inference and model choice in a hidden stochastic two-compartment model of hematopoietic stem cell fate decisions [PDF]
Annals of Applied Statistics 2009, Vol. 3, No. 4, 1695-1709, 2010 Despite rapid advances in experimental cell biology, the in vivo behavior of hematopoietic stem cells (HSC) cannot be directly observed and measured. Previously we modeled feline hematopoiesis using a two-compartment hidden Markov process that had birth and emigration events in the first compartment.
Abkowitz, Janis +2 more
arxiv +3 more sources
Efficient Transition Probability Computation for Continuous-Time Branching Processes via Compressed Sensing [PDF]
arXiv, 2015 Branching processes are a class of continuous-time Markov chains (CTMCs) with ubiquitous applications. A general difficulty in statistical inference under partially observed CTMC models arises in computing transition probabilities when the discrete state space is large or uncountable.
Minin, Vladimir N., Xu, Jason
arxiv +4 more sources
CD14+ monocytes repress gamma globin expression at early stages of erythropoiesis
Scientific Reports, 2021 In β-hemoglobinopathies, reactivation of gamma- at the expense of beta-globin is a prominent therapeutic option. Expression of the globin genes is not strictly intrinsically regulated during erythropoiesis, supported by the observation that fetal ...
Steven Heshusius +3 more
doaj +1 more source
A Plethora of Functions Condensed into Tiny Phospholipids: The Story of PI4P and PI(4,5)P2
Cells, 2023 Phosphoinositides (PIs) are small, phosphorylated lipids that serve many functions in the cell. They regulate endo- and exocytosis, vesicular trafficking, actin reorganization, and cell mobility, and they act as signaling molecules. The most abundant PIs
Ana Bura +4 more
doaj +1 more source
BMC Bioinformatics, 2022 Background Although both copy number variations (CNVs) and single nucleotide variations (SNVs) detected by single-cell RNA sequencing (scRNA-seq) are used to study intratumor heterogeneity and detect clonal groups, a software that integrates these two ...
Jeerthi Kannan +4 more
doaj +1 more source
Communications Biology, 2023 TAZ::CAMTA1 is a fusion protein found in over 90% of Epithelioid Hemangioendothelioma (EHE), a rare vascular sarcoma with an unpredictable disease course. To date, how TAZ::CAMTA1 initiates tumour formation remains unexplained.
Emily Neil +4 more
doaj +1 more source
Iron-loaded deferiprone can support full hemoglobinization of cultured red blood cells
Scientific Reports, 2023 Iron, supplemented as iron-loaded transferrin (holotransferrin), is an essential nutrient in mammalian cell cultures, particularly for erythroid cultures.
Joan Sebastián Gallego-Murillo +5 more
doaj +1 more source
Antioxidants, 2023 Adult T cell leukemia/lymphoma (ATLL) is an aggressive T-cell malignancy that develops in some elderly human T-cell leukemia virus (HTVL-1) carriers.
Piyanard Boonnate +2 more
doaj +1 more source