Results 11 to 20 of about 109,190 (303)

Hematopoiesis in numbers [PDF]

open access: yesTrends in Immunology, 2021
Hematopoiesis is a dynamic process in which stem and progenitor cells give rise to the ~10 13 blood and immune cells distributed throughout the human body.
de Boer, Rob J   +5 more
core   +4 more sources

Hematopoiesis. [PDF]

open access: yesCold Spring Harbor Perspectives in Biology, 2012
Enormous numbers of adult blood cells are constantly regenerated throughout life from hematopoietic stem cells through a series of progenitor stages. Accessibility, robust functional assays, well-established prospective isolation, and successful clinical
Schroeder, T., Rieger, M.
core   +3 more sources

Crustacean hematopoiesis [PDF]

open access: yesDevelopmental & Comparative Immunology, 2016
Crustacean hemocytes are important mediators of immune reactions, and the regulation of hemocyte homeostasis is of utmost importance for the health of these animals.
Söderhäll, Irene, Söderhäll, Irene,
core   +5 more sources

Case report of the extramedullary hematopoiesis presented as a hypervascular intracranial mass

open access: yesAdvanced Biomedical Research, 2013
Thalassemia is a hematologic disorder that causes ineffective hematopoiesis and is related to severe anemia, iron overload, extramedullary hematopoiesis, and hepatomegaly. Hepatomegaly is related to significant extramedullary hematopoiesis.
Nazila Tayari   +2 more
doaj   +2 more sources

Hematopoiesis [PDF]

open access: yesDevelopment, 2013
Hematopoiesis – the process by which blood cells are formed – has been studied intensely for over a century using a variety of model systems. There is conservation of the overall hematopoietic process between vertebrates, although some differences do exist.
Madhumita, Jagannathan-Bogdan   +1 more
  +5 more sources

CD14+ monocytes repress gamma globin expression at early stages of erythropoiesis

open access: yesScientific Reports, 2021
In β-hemoglobinopathies, reactivation of gamma- at the expense of beta-globin is a prominent therapeutic option. Expression of the globin genes is not strictly intrinsically regulated during erythropoiesis, supported by the observation that fetal ...
Steven Heshusius   +3 more
doaj   +1 more source

A Plethora of Functions Condensed into Tiny Phospholipids: The Story of PI4P and PI(4,5)P2

open access: yesCells, 2023
Phosphoinositides (PIs) are small, phosphorylated lipids that serve many functions in the cell. They regulate endo- and exocytosis, vesicular trafficking, actin reorganization, and cell mobility, and they act as signaling molecules. The most abundant PIs
Ana Bura   +4 more
doaj   +1 more source

CAISC: A software to integrate copy number variations and single nucleotide mutations for genetic heterogeneity profiling and subclone detection by single-cell RNA sequencing

open access: yesBMC Bioinformatics, 2022
Background Although both copy number variations (CNVs) and single nucleotide variations (SNVs) detected by single-cell RNA sequencing (scRNA-seq) are used to study intratumor heterogeneity and detect clonal groups, a software that integrates these two ...
Jeerthi Kannan   +4 more
doaj   +1 more source

Iron-loaded deferiprone can support full hemoglobinization of cultured red blood cells

open access: yesScientific Reports, 2023
Iron, supplemented as iron-loaded transferrin (holotransferrin), is an essential nutrient in mammalian cell cultures, particularly for erythroid cultures.
Joan Sebastián Gallego-Murillo   +5 more
doaj   +1 more source

Shikonin Induces ROS-Dependent Apoptosis Via Mitochondria Depolarization and ER Stress in Adult T Cell Leukemia/Lymphoma

open access: yesAntioxidants, 2023
Adult T cell leukemia/lymphoma (ATLL) is an aggressive T-cell malignancy that develops in some elderly human T-cell leukemia virus (HTVL-1) carriers.
Piyanard Boonnate   +2 more
doaj   +1 more source

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