Results 11 to 20 of about 109,190 (303)
Hematopoiesis in numbers [PDF]
Hematopoiesis is a dynamic process in which stem and progenitor cells give rise to the ~10 13 blood and immune cells distributed throughout the human body.
de Boer, Rob J +5 more
core +4 more sources
Enormous numbers of adult blood cells are constantly regenerated throughout life from hematopoietic stem cells through a series of progenitor stages. Accessibility, robust functional assays, well-established prospective isolation, and successful clinical
Schroeder, T., Rieger, M.
core +3 more sources
Crustacean hematopoiesis [PDF]
Crustacean hemocytes are important mediators of immune reactions, and the regulation of hemocyte homeostasis is of utmost importance for the health of these animals.
Söderhäll, Irene, Söderhäll, Irene,
core +5 more sources
Case report of the extramedullary hematopoiesis presented as a hypervascular intracranial mass
Thalassemia is a hematologic disorder that causes ineffective hematopoiesis and is related to severe anemia, iron overload, extramedullary hematopoiesis, and hepatomegaly. Hepatomegaly is related to significant extramedullary hematopoiesis.
Nazila Tayari +2 more
doaj +2 more sources
Hematopoiesis – the process by which blood cells are formed – has been studied intensely for over a century using a variety of model systems. There is conservation of the overall hematopoietic process between vertebrates, although some differences do exist.
Madhumita, Jagannathan-Bogdan +1 more
+5 more sources
CD14+ monocytes repress gamma globin expression at early stages of erythropoiesis
In β-hemoglobinopathies, reactivation of gamma- at the expense of beta-globin is a prominent therapeutic option. Expression of the globin genes is not strictly intrinsically regulated during erythropoiesis, supported by the observation that fetal ...
Steven Heshusius +3 more
doaj +1 more source
A Plethora of Functions Condensed into Tiny Phospholipids: The Story of PI4P and PI(4,5)P2
Phosphoinositides (PIs) are small, phosphorylated lipids that serve many functions in the cell. They regulate endo- and exocytosis, vesicular trafficking, actin reorganization, and cell mobility, and they act as signaling molecules. The most abundant PIs
Ana Bura +4 more
doaj +1 more source
Background Although both copy number variations (CNVs) and single nucleotide variations (SNVs) detected by single-cell RNA sequencing (scRNA-seq) are used to study intratumor heterogeneity and detect clonal groups, a software that integrates these two ...
Jeerthi Kannan +4 more
doaj +1 more source
Iron-loaded deferiprone can support full hemoglobinization of cultured red blood cells
Iron, supplemented as iron-loaded transferrin (holotransferrin), is an essential nutrient in mammalian cell cultures, particularly for erythroid cultures.
Joan Sebastián Gallego-Murillo +5 more
doaj +1 more source
Adult T cell leukemia/lymphoma (ATLL) is an aggressive T-cell malignancy that develops in some elderly human T-cell leukemia virus (HTVL-1) carriers.
Piyanard Boonnate +2 more
doaj +1 more source

