Results 151 to 160 of about 84,742 (296)

Identifying Myeloid‐Derived Suppressor Cells and Lipocalin‐2 as Therapeutic Targets for Intervertebral Disc Degeneration

Advanced Science, EarlyView.
Inflammatory dysregulation drives intervertebral disc degeneration via stage‐dependent immune cellular dynamics. Single‐cell transcriptomics and genetic risk mapping revealed a shift from LCN2high myeloid‐derived suppressor cells maintaining disc repair in early stages to IL1B+ macrophage‐dominated pathology in advanced disease.
Changmeng Zhang, Haoyun Li, Hongfei Wang, Liangyu Shi, Ying Shing Chan, Yu Wang, Graham Ka Hon Shea   +6 more
wiley   +1 more source

Refractory hemorrhage in chronic subdural hematoma: primary myelofibrosis with subdural extramedullary hematopoiesis. Illustrative case. [PDF]

J Neurosurg Case Lessons
Shomura K, Nakashima Y, Kurose N, Ohata K, Fujisawa H.   +4 more
europepmc   +1 more source

RESTORATION OF HEMATOPOIESIS IN DOGS BY INFUSION OF CRYOPRESERVED AUTOLOGOUS PERIPHERAL WHITE CELLS FOLLOWING BUSULFAN-CYCLOPHOSPHAMIDE TREATMENT

, 1975
Kim M. Debelak-Fehir, Robert B. Epstein
openalex   +1 more source

Lithium stimulation of murine hematopoiesis in liquid culture: an effect mediated by marrow stromal cells [PDF]

, 1984
PJ Quesenberry, MA Coppola, RJ Gualtieri, PM Wade, Z Song, MA Doukas, CE Shideler, Baker Dg, EH McGrath   +8 more
openalex   +1 more source

Kindlin Regulates Mechanosensitive Activation and Adhesion Assembly of Integrin beta6

Advanced Science, EarlyView.
Extracellular matrix compliance plays a critical role in the regulation of integrin‐mediated adhesion and cell motility. Here, it is reported that strengthening the kindlin2‐integrin β6 interaction overcomes the dependence on extracellular substrate stiffness and promotes integrin β6‐mediated cell migration.
Wan Ning Lee, Jiamin Li, Nan‐Peng Chen, Cheng‐han Yu   +3 more
wiley   +1 more source

TGF-β inhibition restores hematopoiesis and immune balance via bone marrow EPCs in aplastic anemia. [PDF]

Exp Mol Med
Zhang XY, Guo LP, Wang YZ, Jia JS, Liang M, Shen MZ, Wang ZK, Zhang ZW, Li CY, Lyu ZS, Xing T, Zhang YY, Huang XJ, Kong Y.   +13 more
europepmc   +1 more source

Antigenic analysis of hematopoiesis: II. Expression of human neutrophil antigens on normal and leukemic marrow cells [PDF]

, 1984
LC Strauss, KM Skubitz, JT August, CI Civin   +3 more
openalex   +1 more source

Coactosin‐Like Protein Reduces Prostaglandin D2 Production in Alveolar Macrophages and Alleviates Allergic Airway Inflammation

Advanced Science, EarlyView.
Coactosin‐like protein inhibits prostaglandin D₂ (PGD2) secretion by modulating alveolar macrophage polarization, thereby suppressing activation of the PGD2 receptor CRTH2 in Th2‐associated immune cells and alleviating allergic airway inflammation.
Li‐Long Pan, Zhengnan Ren, Binbin Li, Wenjie Liang, Yang Luo, Qin Yang, He Liu, Xiaoliang Dong, Haizhi Tian, Huimin Zou, Bengt Samuelsson, Olof Rådmark, Jia Sun   +12 more
wiley   +1 more source

BCAS2 promotes primitive hematopoiesis by sequestering β-catenin within the nucleus. [PDF]

Elife
Ning G, Lin Y, Ma H, Zhang J, Yang L, Liu Z, Li L, He X, Wang Q.   +8 more
europepmc   +1 more source

Post‐Translational Modified Neoantigens in Autoimmune Diseases: Challenges of Immune Tolerance

Advanced Science, EarlyView.
Autoimmune diseases have a high incidence and disability rate. The pathogenesis of autoimmune diseases involves the interaction among genetic factors, environmental factors, and immune disorders. The post‐translational modified neoantigens are the key nodal of these three factors. And these post‐translational modified neoantigens, after being presented
Yue Zhai, Kefei Wu, Qi Lin, Zhenzhen Cao, Yankun Jia, Ping Zhu   +5 more
wiley   +1 more source