Results 191 to 200 of about 157,726 (359)

A Novel Therapeutic Strategy for Bone Marrow Failure: Niche Rejuvenation Using Costal Cartilage‐Derived Stem Cells

open access: yesAdvanced Science, EarlyView.
CDSCs exhibit the potential to differentiate into endothelial cells, vascular pericytes, and osteoblasts. These differentiated cells are capable of secreting additional pro‐hematopoietic cytokines. Furthermore, CDSCs can inhibit apoptosis and reduce DNA damage in injured hematopoietic stem and progenitor cells (HSPCs, including RHSCs and RHPCs), while ...
Rui Dong   +16 more
wiley   +1 more source

Effect of age on hematopoiesis in man [PDF]

open access: bronze, 1984
DA Lipschitz   +3 more
openalex   +1 more source

SemiLT: A Multianchor Transfer Learning Method for Cross‐Modality Cell Label Annotation from scRNA‐seq to scATAC‐seq

open access: yesAdvanced Science, EarlyView.
A multianchor transfer learning method, SemiLT, enables accurate cell label annotation in sparse scATAC‐seq data by leveraging well‐annotated scRNA‐seq references. By addressing temporal discrepancies between modalities, SemiLT improves rare cell type identification and batch correction.
Zhitong Chen   +3 more
wiley   +1 more source

Type 2 Diabetes‐Associated Phenylacetylglutamine Induces Deleterious Inflammation Cycle in Myeloid Cells through β2 Adrenergic Receptors and Impedes Wound Healing

open access: yesAdvanced Science, EarlyView.
The microbiota‐derived metabolite phenylacetylglutamine (PAGln) is elevated in type 2 diabetes and tightly associated with poor healing in both diabetic and non‐diabetic human patients. PAGln promotes mouse inflammation and impairs healing through a transmissible β2‐adrenergic receptor–mediated trained‐immunity loop.
Lu Huang   +12 more
wiley   +1 more source

Synergistic Promotion of Triple‐Negative Breast Cancer Tumorigenesis and Metastasis by Oral Polystyrene Nanoplastics Exposure via Alloprevotella‐Derived Glutamate and Platelet Activation

open access: yesAdvanced Science, EarlyView.
Polystyrene nanoplastics (PS‐NPs) administered via oral exposure accelerate triple‐negative breast cancer (TNBC) progression by synergistically modulating gut microbiota‐derived glutamate production and platelet activation. This study uncovers a pivotal crosstalk between microbial metabolites and platelet‐tumor interactions, offering mechanistic ...
Leilei Zhu   +9 more
wiley   +1 more source

A rare case of extramedullary hematopoiesis: when the pericardium produces blood cells. [PDF]

open access: yesEgypt Heart J
Hayar SE   +9 more
europepmc   +1 more source

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