Results 251 to 260 of about 90,270 (303)

Mitochondrial Transplantation as a Therapeutic Strategy for Inherited Mitochondrial Diseases

open access: yesAdvanced Science, EarlyView.
Mitochondrial transplantation (MTx) offers a promising therapeutic avenue for mitochondrial diseases. This review comprehensively evaluates MTx, differentiating its feasibility for mtDNA‐ and nDNA‐based disorders. It examines its potential for genetic correction, alongside inherent limitations, technical challenges, and crucial ethical considerations ...
Parmeshar Singh   +17 more
wiley   +1 more source

Clonal Hematopoiesis and Kidney Function in the ASPREE Cohort. [PDF]

open access: yesKidney Int Rep
Singh J   +16 more
europepmc   +1 more source

Prpf4 sequentially regulates the expansion and maturation of erythrocyte through distinct mechanisms. [PDF]

open access: yesCell Death Discov
Deng Z   +11 more
europepmc   +1 more source

Hematopoiesis

Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy, 1992
Hematopoiesis begins with the pluripotent stem cell in the marrow and culminates in mature, functional red blood cells, white blood cells, and platelets in the circulation. The process consists of a complex and well‐orchestrated sequence of cell proliferation, differentiation, and maturation, that is stimulated and regulated by a host of cytokines and ...
S P, Smith, G C, Yee
openaire   +3 more sources

Embryonic hematopoiesis

Blood Cells, Molecules, and Diseases, 2013
Blood cells are continually produced from a pool of progenitors that derive from hematopoietic stem cells (HSCs). In vertebrates, the hematopoietic system develops from two distinct waves or generation of precursors. The first wave occurs in the yolk sac, in mammals or equivalent embryonic structure, and produces nucleated primitive erythrocytes that ...
Golub, Rachel, Cumano, Ana
openaire   +3 more sources

Developmental Hematopoiesis

Critical Reviews™ in Immunology, 1998
Hematopoiesis is a developmental process that evolves throughout the lifespan of an individual. Most work in the field has focused on events occurring in the adult bone marrow (BM). In the embryo, blood and endothelial cell generation begins very early after gastrulation, in defined intraembryonic mesodermic sites.
Morales-Alcelay, S.   +6 more
openaire   +3 more sources

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