This work reports a Ni‐doped ZIF‐8 nanoplatform co‐encapsulating glucose oxidase and horseradish peroxidase, enabling a cascade catalytic reaction that produces hydroxyl radicals from endogenous glucose and hydrogen peroxide. Upon near‐infrared irradiation, the system simultaneously achieves photothermal and chemodynamic therapy, offering an effective ...
Jing Xu +8 more
wiley +1 more source
Interactions of Hematopoietic and Associated Mesenchymal Stem Cell Populations in the Bone Marrow Microenvironment, In Vivo and In Vitro Model. [PDF]
Bačenková D +4 more
europepmc +1 more source
Remethylation of Dnmt3a−/− hematopoietic cells is associated with partial correction of gene dysregulation and reduced myeloid skewing [PDF]
Bangert, Celia V. +17 more
core +1 more source
Conceptual diagram and schematic illustration of microenvironmental changes in individuals with ASBO before and after treatment. BMSC@Gel therapy transforms the ASBO microenvironment from an inflammatory, fibrotic state with aberrant matrix deposition and barrier dysfunction to a regenerative state with reduced inflammation and improved structural ...
Lihong Zheng * +7 more
wiley +1 more source
Defining the Tumor-Bone axis: the role of extracellular vesicles in a crucial exchange route for breast cancer development and progression. [PDF]
Coronado-Alvarado CD +1 more
europepmc +1 more source
Neonatal bone fragments for the induction of xenograft acceptance: Transplantation of xenogeneic hematopoietic stem cells and species-specific microenvironment for hematopoiesis [PDF]
Demetris, AJ +5 more
core +1 more source
The precise regulation of AP2M1 is essential for normal hematopoiesis. Overexpression of AP2M1 negatively affects the clinical outcomes of AML patients. Upregulation of AP2M1 enhances stemness and chemoresistance in HSPC cells of AML. AP2M1 modulates NOTCH1 expression, enhancing the Notch1 signaling pathway.
Hansong Lee +28 more
wiley +1 more source
Retraction of Sorting protein VPS33B regulates exosomal autocrine signaling to mediate hematopoiesis and leukemogenesis. [PDF]
Gu H +24 more
europepmc +1 more source
Identifying Key Questions and Challenges in Microchimerism Biology
This study identifies key unanswered questions about microchimerism, the presence of cells from one individual living in another. Experts highlight how these cells may affect health, pregnancy, and disease. This study outlines research priorities and challenges in detecting and studying these rare microchimeric cells, aiming to guide future discoveries
Kristine J. Chua +31 more
wiley +1 more source

