Results 41 to 50 of about 5,668,323 (316)

The dynamics of RUNX1-RUNX1T1 transcript levels after allogeneic hematopoietic stem cell transplantation predict relapse in patients with t(8;21) acute myeloid leukemia

Journal of Hematology & Oncology, 2017
Background The optimal monitoring schedules and cutoff minimal residual disease (MRD) levels for the accurate prediction of relapse at all time points after allogeneic hematopoietic stem cell transplantation (allo-HSCT) remain unclear in patients with t ...
Ya-Zhen Qin, Yu Wang, Lan-Ping Xu, Xiao-Hui Zhang, Huan Chen, Wei Han, Yu-Hong Chen, Feng-Rong Wang, Jing-Zhi Wang, Yao Chen, Xiao-Dong Mo, Xiao-Su Zhao, Ying-Jun Chang, Kai-Yan Liu, Xiao-Jun Huang   +14 more
doaj   +1 more source

A four-stage model for murine natural killer cell development in vivo

Journal of Hematology & Oncology, 2022
Natural killer (NK) cells are the predominant innate lymphoid cells that mediate anti-viral and anti-tumor immunity. NK cells arise from hematopoietic stem cells in the bone marrow (BM) and undergo lineage specification and maturation.
Shoubao Ma, Michael A. Caligiuri, Jianhua Yu   +2 more
doaj   +1 more source

Bone Mineral Density After Contemporary Treatment for Acute Lymphoblastic Leukaemia: A Matched Cross‐Sectional Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Reduced bone mineral density (BMD) has been reported in survivors of childhood and young adult acute lymphoblastic leukaemia (ALL); however, data from cohorts treated with contemporary protocols and including matched controls remain limited.
Karen Schow Jensen, Mette Tiedemann Skipper, Niels Holtum Birkebæk, Kjeld Schmiegelow, Thomas Leth Frandsen, Bente Langdahl, Rikke Beck Jensen, Asger Roer Pedersen, Christian Mølgaard, Liv Andrés‐Jensen, Birgitte Klug Albertsen   +10 more
wiley   +1 more source

Sinusoidal obstruction syndrome

Journal of Bone Marrow Transplantation and Cellular Therapy
Objectives: To provide an updated version of the Sociedade Brasileira de Terapia Celular e Transplante de Medula Óssea (SBTMO) 2021 consensus on sinusoidal obstruction syndrome/veno-occlusive disease (SOS/VOD), incorporating recent evidence regarding ...
Fernanda Ribeiro Santos, Marco Salvino, Roselene Mesquita Augusto Passos, Luiz Henrique Assis, Natalia Maria Tavares Ferreira Borges, Nelson Hamerschlak, Eduardo José de Alencar Paton   +6 more
doaj   +1 more source

Compassionate use of ruxolitinib in acute and chronic graft versus host disease refractory both to corticosteroids and extracorporeal photopheresis

Experimental Hematology & Oncology, 2017
Background Ruxolitinib is a potent inhibitor of JAK1/2 with proven efficacy in myelofibrosis. In recent years, research in graft versus host disease (GVHD) has revealed the role of activation of JAK pathways in alloreactive lymphocytes. Some reports have
Mauricio Sarmiento Maldonado, Pablo Ramírez Villanueva, Pablo Bertín Cortes-Monroy, Veronica Jara Arias, Katherine Soto Donoso, Pablo Uribe Gonzalez, Mauricio Ocqueteau Tachini, Jose Antonio Perez-Simón   +7 more
doaj   +1 more source

Perforin gene transfer into hematopoietic stem cells improves immune dysregulation in murine models of perforin deficiency [PDF]

, 2015
Defects in perforin lead to the failure of T and NK cell cytotoxicity, hypercytokinemia, and the immune dysregulatory condition known as familial hemophagocytic lymphohistiocytosis (FHL).
Montiel-Equihua, CA, Arumugam, P, Carmo, M, Risma, KA, Blundell, MP, Hontz, AE, Jordan, MB, Gaspar, HB, Malik, P, Thrasher, AJ, Tiwari, S, Schambach, A, Baum, C, Alonso-Ferrero, ME   +13 more
core  

Identifying Patterns of Hospitalizations Among Childhood Cancer Survivors: A Population‐Based Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Childhood cancer survivors (CCSs) experience more hospitalizations than the general population. We aimed to identify distinct hospitalization patterns among Queensland CCSs and the associated characteristics. Methods Cases (aged ≤14 years) diagnosed between 1995 and 2019 while residents of Queensland were identified through the ...
Hai Pham, Teyl Engstrom, Peter Baade, Natalie Bradford, Sarah Pont, Louise Marquart‐Wilson, Natasha Nassar, Jason D. Pole   +7 more
wiley   +1 more source

TP53 mutations are associated with CD19− relapse and inferior outcomes after blinatumomab in adults with ALL

Blood Advances
: Despite the success of the CD19 × CD3 T-cell engager blinatumomab in B-cell acute lymphoblastic leukemia (B-ALL), treatment failure is common and can manifest with antigen loss and extramedullary disease (EMD) relapse.
Ibrahim Aldoss, Shanpeng Li, Jianying Zhang, Mary C. Clark, Vaibhav Agrawal, Hoda Pourhassan, Paul Koller, Ahmed Aribi, Haris Ali, Amanda Blackmon, Salman Otoukesh, Karamjeet Sandhu, Brian Ball, Shukaib Arslan, Andrew Artz, Idoroenyi Amanam, Monzr M. Al Malki, Amandeep Salhotra, Tibor Kovacsovics, Lindsey Murphy, Michelle Afkhami, Dat Ngo, Jose Tinajero, Zhaohui Gu, Pamela S. Becker, Ryotaro Nakamura, Anthony Stein, Guido Marcucci, Stephen J. Forman, Vinod Pullarkat   +29 more
doaj   +1 more source

Correction to: Minimal residual disease- and graft-vs.-host disease-guided multiple consolidation chemotherapy and donor lymphocyte infusion prevent second acute leukemia relapse after allotransplant

Journal of Hematology & Oncology, 2019
The original article [1] contains two errors in the MRD Testing sub-section of the Methods:
Chen-Hua Yan, Yu Wang, Jing-Zhi Wang, Yu-Hong Chen, Yao Chen, Feng-rong Wang, Yu-Qian Sun, Xiao-Dong Mo, Wei Han, Huan Chen, Xiao-hui Zhang, Lan-Ping Xu, Kai-Yan Liu, Xiao-Jun Huang   +13 more
doaj   +1 more source

CMV IN HEMATOPOIETIC STEM CELL TRANSPLANTATION [PDF]

Mediterranean Journal of Hematology and Infectious Diseases, 2016
Due to its negative impact in the outcome of stem cell transplant (SCT) and solid organ transplant patients (SOT) CMV has been called “the troll of transplantation”. One of the greatest advances in the management of SCT has been the introduction of the preemptive strategy.
openaire   +4 more sources